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Sambú
Darién Province
Panama
Mexico and Central America
Hotwire.com

Sambú Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Decapolis Hotel Panama City

4 out of 5

Price was $1,171, price is now $838 per person

$838

per person

Nov 22 - Nov 26

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Price was $3,022, price is now $1,432 per person

$1,432

per person

Dec 30 - Jan 4

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

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Reviewed on Oct 10, 2026

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $2,058, price is now $1,128 per person

$1,128

per person

Nov 22 - Nov 26

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Riande Aeropuerto Hotel & Casino

4 out of 5

Price was $1,255, price is now $842 per person

$842

per person

Nov 22 - Nov 26

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Nice place for a 1 night stay. Nothing fancy. Rooms and hotel a little outdated but the breakfast was good. So a nice place for a 1 night stay during a layover.

Reviewed on Oct 10, 2026

Casa Mallet by Wynwood House

3.5 out of 5

Price was $3,227, price is now $2,329 per person

$2,329

per person

Dec 30 - Jan 4

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect. The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us. I would stay here again in a heart beat. It’s a must stay!

Reviewed on Sep 16, 2026

Hotel Riu Plaza Panama

5 out of 5

Price was $1,220, price is now $887 per person

$887

per person

Nov 22 - Nov 26

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Villa Caprichosa

2.5 out of 5

Price was $2,421, price is now $1,835 per person

$1,835

per person

Dec 30 - Jan 5

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Book a stay at this beach hotel in Taboga. Enjoy free breakfast, free WiFi, and a free ferry terminal shuttle. Popular attraction Taboga Beach is located nearby.

Amarla Boutique Hotel Casco Viejo Adults Only

3 out of 5

Price was $2,000, price is now $1,533 per person

$1,533

per person

Nov 11 - Nov 16

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Stay at this hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Nice place! Reception was a little small, but we only stayed one night and it was just fine. Probably not where I would stay for a long trip or if I needed to spread out, but the room was clean and comfortable. I loved the silk robes!

Reviewed on Oct 1, 2026