Search Deals on
Río Sereno Vacation Packages

Build your package with 2 more options

Río Sereno Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,083, price is now $571 per person
$571
per person
Apr 5 - Apr 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,401, price is now $851 per person
$851
per person
Apr 5 - Apr 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Save 100% on your flight
Price was $1,258, price is now $803 per person
$803
per person
Apr 5 - Apr 11
found 16 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Save 100% on your flight
Price was $2,096, price is now $1,373 per person
$1,373
per person
Mar 6 - Mar 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Villa Marina Lodge & Condos

Villa Marina Lodge & Condos

3.5 out of 5
Price was $980, price is now $661 per person
$661
per person
Apr 23 - Apr 28
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Book a stay at this beach inn in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. Popular attraction Venao Beach is located nearby.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,507, price is now $1,041 per person
$1,041
per person
Mar 6 - Mar 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,507, price is now $1,064 per person
$1,064
per person
Mar 6 - Mar 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Save 100% on your flight
Price was $3,088, price is now $2,229 per person
$2,229
per person
Mar 6 - Mar 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Río Sereno Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $718, price is now $520 per person
$520
per person
Apr 2 - Apr 5
found 21 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,083, price is now $571 per person
$571
per person
Apr 5 - Apr 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,401, price is now $851 per person
$851
per person
Apr 5 - Apr 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $942, price is now $674 per person
$674
per person
Apr 5 - Apr 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Río Sereno Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,230, price is now $597 per person
$597
per person
Apr 17 - Apr 22
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,663, price is now $934 per person
$934
per person
Apr 17 - Apr 22
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Save 100% on your flight
Price was $1,258, price is now $803 per person
$803
per person
Apr 5 - Apr 11
found 16 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $2,096, price is now $1,373 per person
$1,373
per person
Mar 6 - Mar 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Wed, Apr 8 - Thu, Apr 9
SJO
Juan Santamaría Intl.
DAV
Enrique Malek Intl.
$272 Roundtrip, found 1 day ago
$272
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, Apr 8 from Juan Santamaría Intl. to Enrique Malek Intl., returning Thu, Apr 9, priced at $272 found 1 day ago
Euroairlines
Fri, Jan 30 - Thu, Feb 5
PAC
Marcos A. Gelabert Intl.
BOC
Bocas del Toro Intl.
$343 Roundtrip, found 4 days ago
$343
Roundtrip
found 4 days ago
Select Euroairlines flight, departing Fri, Jan 30 from Marcos A. Gelabert Intl. to Bocas del Toro Intl., returning Thu, Feb 5, priced at $343 found 4 days ago
APG Distribution System
Sun, Feb 15 - Sun, Feb 15
PAC
Marcos A. Gelabert Intl.
DAV
Enrique Malek Intl.
$434 Roundtrip, found 1 day ago
$434
Roundtrip
found 1 day ago
Select APG Distribution System flight, departing Sun, Feb 15 from Marcos A. Gelabert Intl. to Enrique Malek Intl., returning Sun, Feb 15, priced at $434 found 1 day ago
Copa
Tue, Feb 24 - Tue, Mar 3
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$570 Roundtrip, found 2 hours ago
$570
Roundtrip
found 2 hours ago
Select Copa flight, departing Tue, Feb 24 from Miami Intl. to Enrique Malek Intl., returning Tue, Mar 3, priced at $570 found 2 hours ago