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Río Sereno Vacation Packages

Build your package with 2 more options

Río Sereno Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Punta Chame Club and Resort

Punta Chame Club and Resort

4 out of 5
Price was $1,111, price is now $821 per person
$821
per person
Aug 7 - Aug 14
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Panama City (PTY)
Stay at this aparthotel in Pajonal. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Playa Malibú and Kevin Castle are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,857, price is now $1,192 per person
$1,192
per person
Jul 2 - Jul 6
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was $1,442, price is now $1,035 per person
$1,035
per person
Aug 3 - Aug 10
found 10 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Book a stay at this beach inn in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. Popular attraction Venao Beach is located nearby.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,333, price is now $964 per person
$964
per person
Jul 2 - Jul 6
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Price was $1,783, price is now $1,317 per person
$1,317
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,136, price is now $848 per person
$848
per person
Jul 2 - Jul 6
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Price was $1,632, price is now $1,220 per person
$1,220
per person
Aug 12 - Aug 19
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa Madre Tierra

Casa Madre Tierra

3 out of 5
Price was $1,134, price is now $855 per person
$855
per person
Aug 7 - Aug 14
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Panama City (PTY)
Stay at this hotel in Los Llanitos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Valley of Square Trees and Square Trees Nature Trail are located nearby.

Río Sereno Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Smart Loft-style 1br Apt Near to Shops

Smart Loft-style 1br Apt Near to Shops

2 out of 5
San Francisco
Price was $923, price is now $710 per person
$710
per person
Jul 7 - Jul 10
found 1 hour ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,857, price is now $1,192 per person
$1,192
per person
Jul 2 - Jul 6
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,333, price is now $964 per person
$964
per person
Jul 2 - Jul 6
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,136, price is now $848 per person
$848
per person
Jul 2 - Jul 6
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)

Río Sereno Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,356, price is now $935 per person
$935
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,935, price is now $1,073 per person
$1,073
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar

3.5 out of 5
San Francisco
Save 100% on your flight
Price was $3,902, price is now $2,625 per person
$2,625
per person
Jul 11 - Jul 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,466, price is now $993 per person
$993
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sun, Jul 12 - Fri, Jul 17
PTY
Tocumen Intl.
DAV
Enrique Malek Intl.
$85 Roundtrip, found 5 days ago
$85
Roundtrip
found 5 days ago
Select Copa flight, departing Sun, Jul 12 from Tocumen Intl. to Enrique Malek Intl., returning Fri, Jul 17, priced at $85 found 5 days ago
Copa
Sun, Sep 20 - Wed, Oct 7
FLL
Fort Lauderdale - Hollywood Intl.
DAV
Enrique Malek Intl.
$420 Roundtrip, found 1 day ago
$420
Roundtrip
found 1 day ago
Select Copa flight, departing Sun, Sep 20 from Fort Lauderdale - Hollywood Intl. to Enrique Malek Intl., returning Wed, Oct 7, priced at $420 found 1 day ago
Copa
Thu, Aug 13 - Sun, Aug 23
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$470 Roundtrip, found 6 hours ago
$470
Roundtrip
found 6 hours ago
Select Copa flight, departing Thu, Aug 13 from Miami Intl. to Enrique Malek Intl., returning Sun, Aug 23, priced at $470 found 6 hours ago
Copa
Thu, Aug 27 - Sat, Oct 3
JFK
John F. Kennedy Intl.
DAV
Enrique Malek Intl.
$598 Roundtrip, found 1 day ago
$598
Roundtrip
found 1 day ago
Select Copa flight, departing Thu, Aug 27 from John F. Kennedy Intl. to Enrique Malek Intl., returning Sat, Oct 3, priced at $598 found 1 day ago