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Río Sereno Vacation Packages

Build your package with 2 more options

Río Sereno Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Casa Contemporanea by Wynwood House

Casa Contemporanea by Wynwood House

4 out of 5
Price was $1,168, price is now $879 per person
$879
per person
Aug 22 - Aug 29
found 1 day ago
Roundtrip flight included
Nassau (NAS) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, satellite TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,977, price is now $1,293 per person
$1,293
per person
Aug 11 - Aug 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Las Clementinas

Las Clementinas

3.5 out of 5
Price was $1,656, price is now $1,127 per person
$1,127
per person
Aug 11 - Aug 18
found 3 hours ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,642, price is now $1,133 per person
$1,133
per person
Aug 11 - Aug 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,377, price is now $954 per person
$954
per person
Aug 11 - Aug 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Price was $1,862, price is now $1,348 per person
$1,348
per person
Aug 5 - Aug 11
found 1 day ago
Roundtrip non-stop flight included
Washington (IAD) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $2,294, price is now $1,705 per person
$1,705
per person
Aug 11 - Aug 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,363, price is now $1,028 per person
$1,028
per person
Jul 8 - Jul 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Río Sereno Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,108, price is now $763 per person
$763
per person
Aug 20 - Aug 23
found 3 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,687, price is now $983 per person
$983
per person
Jul 9 - Jul 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,373, price is now $947 per person
$947
per person
Jul 8 - Jul 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
Price was $1,363, price is now $1,028 per person
$1,028
per person
Jul 8 - Jul 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Río Sereno Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,377, price is now $954 per person
$954
per person
Aug 11 - Aug 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,977, price is now $1,293 per person
$1,293
per person
Aug 11 - Aug 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Las Clementinas

Las Clementinas

3.5 out of 5
Casco Viejo
Price was $1,656, price is now $1,127 per person
$1,127
per person
Aug 11 - Aug 18
found 3 hours ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,642, price is now $1,133 per person
$1,133
per person
Aug 11 - Aug 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sun, Jul 12 - Fri, Jul 17
PTY
Tocumen Intl.
DAV
Enrique Malek Intl.
$85 Roundtrip, found 9 hours ago
$85
Roundtrip
found 9 hours ago
Select Copa flight, departing Sun, Jul 12 from Tocumen Intl. to Enrique Malek Intl., returning Fri, Jul 17, priced at $85 found 9 hours ago
Euroairlines
Mon, Jul 13 - Mon, Jul 20
PAC
Marcos A. Gelabert Intl.
BOC
Bocas del Toro Intl.
$350 Roundtrip, found 9 hours ago
$350
Roundtrip
found 9 hours ago
Select Euroairlines flight, departing Mon, Jul 13 from Marcos A. Gelabert Intl. to Bocas del Toro Intl., returning Mon, Jul 20, priced at $350 found 9 hours ago
Copa
Sun, Sep 20 - Wed, Oct 7
FLL
Fort Lauderdale - Hollywood Intl.
DAV
Enrique Malek Intl.
$420 Roundtrip, found 4 days ago
$420
Roundtrip
found 4 days ago
Select Copa flight, departing Sun, Sep 20 from Fort Lauderdale - Hollywood Intl. to Enrique Malek Intl., returning Wed, Oct 7, priced at $420 found 4 days ago
Copa
Wed, Aug 26 - Fri, Sep 4
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$470 Roundtrip, found 21 hours ago
$470
Roundtrip
found 21 hours ago
Select Copa flight, departing Wed, Aug 26 from Miami Intl. to Enrique Malek Intl., returning Fri, Sep 4, priced at $470 found 21 hours ago