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Hotels in Piketon

Choose from 188 Piketon Hotel Deals

Comfort Inn Piketon near Fairgrounds

Comfort Inn Piketon near Fairgrounds

2.5 out of 5
7525 US 23 Piketon OH
  • 9 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly hotel in Piketon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (377 reviews)
"wife liked the spa tub! breakfast was nice."

Reviewed on Jun 1, 2026

Comfort Inn Piketon near Fairgrounds
Town and Country Motel

Town and Country Motel

2.5 out of 5
7137 U.S. 23 Piketon OH
  • 7 min drive from Portsmouth Gaseous Diffusion Plant
Stay at this motel in Piketon. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Piketon Mounds and Big Beaver Creek Golf Club are ...
Town and Country Motel
Christopher Inn and Suites

Christopher Inn and Suites

2.5 out of 5
30 North Plaza Boulevard Chillicothe OH
  • 56 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly hotel in Chillicothe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9/10 Wonderful! (1,278 reviews)
"Breakfast was delicious"

Reviewed on Jun 10, 2026

Christopher Inn and Suites
Super 8 by Wyndham Portsmouth

Super 8 by Wyndham Portsmouth

2 out of 5
4266 US Route 23 N Portsmouth OH
  • 38 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly motel in Portsmouth. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (752 reviews)
"I"

Reviewed on Jun 8, 2026

Super 8 by Wyndham Portsmouth
Quality Inn Jackson

Quality Inn Jackson

2.5 out of 5
605 E Main St Jackson OH
  • 16 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (461 reviews)
"The hotel has plumbing issues, Drains dont work, the plumber was working on something the first 2 hrs I was there the water was shut off. Other areas of the hotel under construction total mess. No attempt to clean anything up. The stairs to the second floor was the construction sulpy room. That was ..."

Reviewed on May 29, 2026

Quality Inn Jackson
Best Western Adena Inn

Best Western Adena Inn

2.5 out of 5
1250 N Bridge Street Chillicothe OH
  • 58 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly hotel in Chillicothe. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and ...
7.8/10 Good! (808 reviews)
"Breakfast was hot, good, and great variety. Only complaint was that they didnt have shower caps at the front desk since the room contained only a shower."

Reviewed on Jun 11, 2026

Best Western Adena Inn
Executive Inn

Executive Inn

2.5 out of 5
24 North Bridge Street Chillicothe OH
  • 54 min drive from Portsmouth Gaseous Diffusion Plant
Stay at this hotel in Chillicothe. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (718 reviews)
"Definitely needs updating. Strange smell in hallway and our room. Neighborhood seemed a bit sketchy. Website says there are 15 rooms here, but this facility has more rooms than that. Just not sure what they are used for. Apparently traveling construction workers were staying there so maybe rooms ..."

Reviewed on Jun 2, 2026

Executive Inn
Jungle House Luxury Stays - Downtown Chillicothe

Jungle House Luxury Stays - Downtown Chillicothe

5 out of 5
241 West Water Street Chillicothe OH
  • 54 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this luxury apartment in Chillicothe. Enjoy free WiFi, free parking, and a 24-hour business center. Popular attractions Yoctangee Park and Majestic ...
9.8/10 Exceptional! (13 reviews)
"Everything was fine but after checking out the owner was holding to the demage depot for a week even though there were no demage to the property"

Reviewed on Jun 5, 2026

Jungle House Luxury Stays - Downtown Chillicothe
Quality Inn Chillicothe

Quality Inn Chillicothe

2.5 out of 5
20 N Plaza Blvd Chillicothe OH
  • 56 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly hotel in Chillicothe. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pump House Center for the ...
8/10 Very Good! (576 reviews)
"Place is very nice. But didn’t realize they didn’t have elevator."

Reviewed on Jun 10, 2026

Quality Inn Chillicothe
Days Inn by Wyndham Jackson

Days Inn by Wyndham Jackson

2 out of 5
972 E Main St. Jackson OH
  • 16 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (417 reviews)
"It was a good overnight stay. Comfortable beds, quiet except for a beeping noise during the night. Not sure where it was coming from."

Reviewed on Jun 6, 2026

Days Inn by Wyndham Jackson
Quality Inn Seaman

Quality Inn Seaman

2.5 out of 5
55 Stern Dr Seaman OH
  • 30 min drive from Portsmouth Gaseous Diffusion Plant
Stay at this hotel in Seaman. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
7.4/10 Good! (303 reviews)
"This property is old and needs improvements. The first room I was in had plumbing issues with. O hot water and a back up in the toilet. When I first got into the room, there was feces waste in the toilet. The staff moved me to a different room and said they had been having problems with the plumbing ..."

Reviewed on May 26, 2026

Quality Inn Seaman
Quality Inn Wheelersburg

Quality Inn Wheelersburg

2.5 out of 5
8226 Ohio River Rd Wheelersburg OH
  • 49 min drive from Portsmouth Gaseous Diffusion Plant
Book a stay at this business-friendly hotel in Wheelersburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (343 reviews)
"Get to the breakfast early or you will miss out."

Reviewed on Jun 7, 2026

Quality Inn Wheelersburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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