Search for Cheap Deals on
Hotels in Osceola

Check Last Minute Osceola Hotel Deals

Tonight Feb 13 - Feb 14This weekend Feb 13 - Feb 15

Choose from 79 Osceola Hotel Deals

Days Inn & Suites by Wyndham Osceola AR

Days Inn & Suites by Wyndham Osceola AR

2 out of 5
4491 W Keiser Ave Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this motel in Osceola. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Florida Park and Osceola Branch Mississippi County Library ...
6.4/10 (369 reviews)
Just what I needed/expected.

Reviewed on Jan 2, 2026

Days Inn & Suites by Wyndham Osceola AR
Holiday Inn Osceola by IHG

Holiday Inn Osceola by IHG

3 out of 5
4630 West Keiser Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Osceola. Enjoy free parking, an outdoor pool, and a 24-hour fitness center. Popular attractions Florida Park and Osceola Branch Mississippi ...
8.8/10 Excellent! (20 reviews)
Staff was courteous. Clean rooms. Restaurant was great.

Reviewed on Feb 5, 2026

Holiday Inn Osceola by IHG
Roadside Inn

Roadside Inn

2.5 out of 5
4635 W Keiser Ave Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Osceola. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Florida Park and Osceola Branch Mississippi County ...
7.4/10 Good! (23 reviews)
Room temperature was great even when we first walked in. Very clean, comfortable and nice. Staff was very friendly and polite. Sure wish they had a coffee pot in the room. Other than that everything was great!

Reviewed on Feb 3, 2026

Roadside Inn
Econo Lodge

Econo Lodge

2 out of 5
4635 W Keiser Avenue Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Osceola. Enjoy a restaurant. Popular attractions Florida Park and Osceola Branch Mississippi County Library are located nearby.
Econo Lodge
Holiday Inn Blytheville by IHG

Holiday Inn Blytheville by IHG

3 out of 5
1121 E Main St Blytheville AR
  • 39 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Blytheville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (666 reviews)
yes

Reviewed on Feb 2, 2026

Holiday Inn Blytheville by IHG
Comfort Inn & Suites Blytheville

Comfort Inn & Suites Blytheville

2.5 out of 5
1510 E Main St Blytheville AR
  • 39 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Blytheville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (700 reviews)
We had a quick and easy check-in, which we were thankful for as we had a long day of travel. The room was clean and appreciated the early breakfast set up since we had to depart early. Thank you!

Reviewed on Jan 15, 2026

Comfort Inn & Suites Blytheville
Hampton Inn Blytheville

Hampton Inn Blytheville

2.5 out of 5
301 N Service Road, I-55 Blytheville AR
  • 39 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Blytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (900 reviews)
Room was quiet and staff were friendly!

Reviewed on Feb 6, 2026

Hampton Inn Blytheville
Hampton Inn & Suites Millington

Hampton Inn & Suites Millington

2.5 out of 5
8838 Highway 51 N Millington TN
  • 56 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Millington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (610 reviews)
Room was nice and clean and very quiet.

Reviewed on Feb 10, 2026

Hampton Inn & Suites Millington
The Louis Hotel

The Louis Hotel

4 out of 5
3 Cross Street Wilson AR
  • 23 min drive from South Mississippi County Regional Medical Center
Book a stay at this golf hotel in Wilson. Enjoy free WiFi, free valet parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (54 reviews)
Stumbled upon this boutique hotel while looking for a place to stay while traveling. So pleased with our decision, as this place surpassed all of our expectations. The architecture follows the English Revival theme of the town. The modern interior is clean and welcoming. We loved the high-thread ...

Reviewed on Feb 2, 2026

The Louis Hotel
Comfort Inn & Suites Atoka-Millington

Comfort Inn & Suites Atoka-Millington

2.5 out of 5
10772 Hwy 51 S. Atoka TN
  • 45 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Atoka. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (460 reviews)
The staff was so helpful!!!

Reviewed on Jan 13, 2026

Comfort Inn & Suites Atoka-Millington
Quality Inn & Suites Covington

Quality Inn & Suites Covington

2.5 out of 5
873 Highway 51 N Covington TN
  • 33 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Covington. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cobb-Parr Memorial Park and Covington Country Club are ...
7/10 Good! (42 reviews)
Great

Reviewed on Jan 14, 2026

Quality Inn & Suites Covington
Holiday Inn Express & Suites Millington by IHG

Holiday Inn Express & Suites Millington by IHG

2.5 out of 5
5090 Cooper Creek Blvd Millington TN
  • 57 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Millington. Enjoy free breakfast, free WiFi, and free parking. Popular attractions E A Harrold Park and Harvell ...
8.2/10 Very Good! (514 reviews)
This is our 3 or 4 Holiday Inn. I love that we can Al stay in 1 room. Saving us money.

Reviewed on Dec 28, 2025

Holiday Inn Express & Suites Millington by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Osceola

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Osceola hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Osceola.

Choosing the right hotel in Arkansas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Osceola’s 79 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $61. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Osceola hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Osceola. No matter your reason for visiting Osceola, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Osceola hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Osceola for as low as $61.

How many hotels are there in Osceola?

With over 79 hotels in Osceola, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $61.

How to find cheap car rentals in Osceola?

Finding a cheap car rental deal in Osceola is as easy as scoring cheap hotels in Osceola. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.