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Mesilla Vacations

Pack those stellar shades. We have Mesilla vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Mesilla – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Mesilla vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Mesilla

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Mesilla vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Mesilla well.

Mesilla Flight + Hotel packages

Top Hotel Deals

See all 49 Hotels in Mesilla
Hotel Mesilla

Hotel Mesilla

1891 Avenida de Mesilla, Mesilla
    3.5 out of 5.0
     
     

    Situated in Mesilla, this hotel is 2.8 mi (4.5 km) from Las Cruces Museum of Art and within 6 mi (10 km) of New Mexico State University and Mesilla Valley Mall. ...

    La Quinta Inn Las Cruces Mesilla Valley

    La Quinta Inn Las Cruces Mesilla Valley

    790 Avenida De Mesilla, Las Cruces
      2.5 out of 5.0
       
       

      Situated in the business district, this hotel is 1.7 mi (2.8 km) from Las Cruces Museum of Art and 3 mi (4.9 km) from New Mexico State University. New Mexico ...

      La Quinta Inn Las Cruces Mesilla Valley$55

      La Quinta Inn Las Cruces Mesilla Valley$55
      Days Inn by Wyndham Las Cruces

      Days Inn by Wyndham Las Cruces

      755 Avenida De Mesilla, Las Cruces
        2.5 out of 5.0
         
         

        Located in the heart of Las Cruces, this hotel is 1.7 mi (2.8 km) from Las Cruces Museum of Art and 3.1 mi (5 km) from New Mexico State University. Mesilla Valley ...

        Days Inn by Wyndham Las Cruces$50

        Days Inn by Wyndham Las Cruces$50
        Hotel Encanto de Las Cruces

        Hotel Encanto de Las Cruces

        705 S Telshor Blvd, Las Cruces
          3.5 out of 5.0
           
           

          Situated in Las Cruces, this spa hotel is 0.1 mi (0.2 km) from Mesilla Valley Mall and within 3 mi (5 km) of New Mexico Farm and Ranch Heritage Museum and New ...

          Hotel Encanto de Las Cruces$83

          Hotel Encanto de Las Cruces$83
          Drury Inn & Suites Las Cruces

          Drury Inn & Suites Las Cruces

          1631 Hickory Loop, Las Cruces
            3.0 out of 5.0
             
             

            Located in the heart of Las Cruces, this hotel is 2 mi (3.3 km) from Las Cruces Museum of Art and within 6 mi (10 km) of New Mexico State University and Mesilla ...

            Ramada Hotel & Conference Center by Wyndham Las Cruces

            Ramada Hotel & Conference Center by Wyndham Las Cruces

            201 E University Avenue, Las Cruces
              3.0 out of 5.0
               
               

              Situated in Las Cruces, this hotel is 1.6 mi (2.5 km) from New Mexico State University and 2.5 mi (4.1 km) from Las Cruces Museum of Art. New Mexico Farm and ...

              Ramada Hotel & Conference Center by Wyndham Las Cruces$76

              Ramada Hotel & Conference Center by Wyndham Las Cruces$76
              Hampton Stes Las Cruces I-10

              Hampton Stes Las Cruces I-10

              1641 Hickory Loop, Las Cruces
                2.5 out of 5.0
                 
                 

                Situated in Las Cruces, this hotel is 2.1 mi (3.4 km) from Las Cruces Museum of Art and within 6 mi (10 km) of New Mexico State University and Mesilla Valley ...

                Hampton Stes Las Cruces I-10$93

                Hampton Stes Las Cruces I-10$93
                La Quinta Inn & Suites Las Cruces Organ Mountain

                La Quinta Inn & Suites Las Cruces Organ Mountain

                1500 Hickory Dr, Las Cruces
                  2.5 out of 5.0
                   
                   

                  Situated in the historical district, this hotel is 1.9 mi (3 km) from Las Cruces Museum of Art and 3 mi (4.9 km) from New Mexico State University. Mesilla Valley ...

                  La Quinta Inn & Suites Las Cruces Organ Mountain$59

                  La Quinta Inn & Suites Las Cruces Organ Mountain$59
                  Motel 6 Las Cruces - Telshor

                  Motel 6 Las Cruces - Telshor

                  2120 Summit Ct, Las Cruces
                    2.0 out of 5.0
                     
                     

                    Situated in Las Cruces, this motel is 2.7 mi (4.3 km) from Mesilla Valley Mall and within 6 mi (10 km) of Las Cruces Museum of Art and New Mexico State University. ...

                    Motel 6 Las Cruces - Telshor$55

                    Motel 6 Las Cruces - Telshor$55
                    Springhill Suites By Marriott Las Cruces

                    Springhill Suites By Marriott Las Cruces

                    1611 Hickory Loop, Las Cruces
                      3.0 out of 5.0
                       
                       

                      Situated in Las Cruces, this hotel is 2.1 mi (3.4 km) from Las Cruces Museum of Art and within 6 mi (10 km) of New Mexico State University and Mesilla Valley ...

                      Springhill Suites By Marriott Las Cruces$89

                      Springhill Suites By Marriott Las Cruces$89

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.