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Mayo Vacations

Pack those stellar shades. We have Mayo vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Mayo – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Mayo vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Mayo

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Mayo vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Mayo well.

Top Hotel Deals

See all 32 Hotels in Mayo
Holiday Inn Express Hotel & Suites LIVE OAK

Holiday Inn Express Hotel & Suites LIVE OAK

6694 Us Highway 129, Live Oak
    2.5 out of 5.0
     
     

    Situated in a rural location, this hotel is 2.4 mi (3.9 km) from Suwannee County Historical Museum and within 6 mi (10 km) of Spirit of the Suwannee Music Park ...

    Holiday Inn Express Hotel & Suites LIVE OAK$129

    Holiday Inn Express Hotel & Suites LIVE OAK$129
    Best Western Plus Madison Inn

    Best Western Plus Madison Inn

    167 SE Bandit Street, Madison
      2.5 out of 5.0
       
       

      Situated in Madison, this hotel is within 6 mi (10 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida ...

      Best Western Plus Madison Inn$176

      Best Western Plus Madison Inn$176
      Royal Inn Motel

      Royal Inn Motel

      1829 South Byron Bulter Parkway, Perry
        2.0 out of 5.0
         
         

        Situated in Perry, this motel is within 2 mi (3 km) of Perry Train Depot, Doctors Memorial Hospital, and Taylor County Historical Society. Forest Capital Museum ...

        Holiday Inn Express Hotel & Suites PERRY

        Holiday Inn Express Hotel & Suites PERRY

        601 Everett Way, Perry
          2.5 out of 5.0
           
           

          Situated in Perry, this hotel is within 12 mi (20 km) of Forest Capital Museum State Park, Perry Train Depot, and Taylor County Historical Society. Doctors Memorial ...

          Holiday Inn Express Hotel & Suites PERRY$135

          Holiday Inn Express Hotel & Suites PERRY$135
          Hampton Inn Perry

          Hampton Inn Perry

          2399 S Byron Butler Pkwy, Perry
            2.5 out of 5.0
             
             

            Situated in a rural location, this hotel is 1.1 mi (1.8 km) from Forest Capital Museum State Park and within 3 mi (5 km) of Perry Train Depot and Taylor County ...

            Hampton Inn Perry$139

            Hampton Inn Perry$139
            Super 8 Madison FL

            Super 8 Madison FL

            6246 State Rd. 53 South, Madison
              2.0 out of 5.0
               
               

              Situated in Madison, this motel is within 6 mi (10 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida ...

              Super 8 Madison FL$90

              Super 8 Madison FL$90
              Econo Lodge Perry

              Econo Lodge Perry

              2220 S Us 19, Perry
                2.0 out of 5.0
                 
                 

                Situated near the airport, this motel is within 2 mi (3 km) of Forest Capital Museum State Park, Perry Train Depot, and Taylor County Historical Society. Doctors ...

                Econo Lodge Perry$66

                Econo Lodge Perry$66
                Quality Inn Live Oak

                Quality Inn Live Oak

                6819 Us Highway 129, Live Oak
                  2.5 out of 5.0
                   
                   

                  Located in the heart of Live Oak, this motel is 1.3 mi (2.2 km) from Suwannee County Historical Museum and within 6 mi (10 km) of First Federal Sportsplex and ...

                  Quality Inn Live Oak$104

                  Quality Inn Live Oak$104
                  Econo Lodge Live Oak

                  Econo Lodge Live Oak

                  6811 N Us 129 & I 10, Live Oak
                    2.0 out of 5.0
                     
                     

                    Located in the heart of Live Oak, this motel is 2.3 mi (3.7 km) from Suwannee County Historical Museum and within 6 mi (10 km) of First Federal Sportsplex and ...

                    Econo Lodge Live Oak$82

                    Econo Lodge Live Oak$82
                    Putnam Lodge Hotel and Spa

                    Putnam Lodge Hotel and Spa

                    15487 Northwest Highway 19, Cross City
                      2.5 out of 5.0
                       
                       

                      Situated near the airport, this spa hotel is within 20 mi (32 km) of Steinhatchee Falls, Sea Hag Marina, and Steinhatchee Public Boat Ramp. Dakotah Winery and ...

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.