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Mayo Vacations

Pack those stellar shades. We have Mayo vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Mayo – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Mayo vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Mayo

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Mayo vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Mayo well.

Top Hotel Deals

See all 32 Properties in Mayo
Days Inn by Wyndham Madison

Days Inn by Wyndham Madison

6160 South State Road 53, Madison
    2.0 out of 5.0
     
     

    Situated in Madison, this motel is within 6 mi (10 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida ...

    Days Inn by Wyndham Madison$60

    Days Inn by Wyndham Madison$60
    Super 8 by Wyndham Madison

    Super 8 by Wyndham Madison

    6246 State Rd. 53 South, Madison
      2.0 out of 5.0
       
       

      Situated in Madison, this motel is within 6 mi (10 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida ...

      Super 8 by Wyndham Madison$63

      Super 8 by Wyndham Madison$63
      Steinhatchee River Inn

      Steinhatchee River Inn

      1111 Riverside Drive, Steinhatchee
        2.0 out of 5.0
         
         

        Situated on a river, this motel is within 1 mi (2 km) of Sea Hag Marina and Steinhatchee Public Boat Ramp. Steinhatchee Falls and Hagen Cove are also within ...

        Steinhatchee River Inn$159

        Steinhatchee River Inn$159
        Best Western Plus Madison Inn

        Best Western Plus Madison Inn

        167 SE Bandit Street, Madison
          2.5 out of 5.0
           
           

          Situated in a rural location, this hotel is within 9 mi (15 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North ...

          Best Western Plus Madison Inn$93

          Best Western Plus Madison Inn$93
          Royal Inn Motel

          Royal Inn Motel

          1829 South Byron Bulter Parkway, Perry
            2.0 out of 5.0
             
             

            Situated in Perry, this motel is within 2 mi (3 km) of Perry Train Depot, Doctors Memorial Hospital, and Taylor County Historical Society. Forest Capital Museum ...

            Royal Inn Motel$49

            Royal Inn Motel$49
            Quality Inn Live Oak

            Quality Inn Live Oak

            6819 Us Highway 129, Live Oak
              2.5 out of 5.0
               
               

              Located in the heart of Live Oak, this motel is 1.3 mi (2.2 km) from Suwannee County Historical Museum and within 6 mi (10 km) of First Federal Sportsplex and ...

              Quality Inn Live Oak$88

              Quality Inn Live Oak$88
              Deerwood Inn and Madison Campground

              Deerwood Inn and Madison Campground

              155 S.W. Old St Augustine Road, Madison
                2.0 out of 5.0
                 
                 

                Situated in Madison, this motel is within 9 mi (15 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida ...

                Deerwood Inn and Madison Campground$68

                Deerwood Inn and Madison Campground$68
                Holiday Inn Express Hotel & Suites LIVE OAK

                Holiday Inn Express Hotel & Suites LIVE OAK

                6694 Us Highway 129, Live Oak
                  2.5 out of 5.0
                   
                   

                  Situated in a rural location, this hotel is 2.4 mi (3.9 km) from Suwannee County Historical Museum and within 6 mi (10 km) of Spirit of the Suwannee Music Park ...

                  Holiday Inn Express Hotel & Suites LIVE OAK$139

                  Holiday Inn Express Hotel & Suites LIVE OAK$139
                  Hampton Inn Perry

                  Hampton Inn Perry

                  2399 S Byron Butler Pkwy, Perry
                    2.5 out of 5.0
                     
                     

                    Situated in a rural location, this hotel is 1.1 mi (1.8 km) from Forest Capital Museum State Park and within 3 mi (5 km) of Perry Train Depot and Taylor County ...

                    Hampton Inn Perry$96

                    Hampton Inn Perry$96
                    Econo Lodge Perry

                    Econo Lodge Perry

                    2220 S Us 19, Perry
                      2.0 out of 5.0
                       
                       

                      Situated near the airport, this motel is within 2 mi (3 km) of Forest Capital Museum State Park, Perry Train Depot, and Taylor County Historical Society. Doctors ...

                      Econo Lodge Perry$50

                      Econo Lodge Perry$50

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.