Search Deals on
Isla Grande Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

Palm trees forest and houses in Isla Grande shore. Colon province, Panama, Caribbean, Central America.

Isla Grande
Colón
Panama
Mexico and Central America
Hotwire.com

Isla Grande Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama

5 out of 5

Price was $962, price is now $625 per person

$625

per person

Feb 26 - Mar 3

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $1,842, price is now $1,043 per person

$1,043

per person

Feb 26 - Mar 3

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Mahogany Suites

2 out of 5

Price was $1,155, price is now $655 per person

$655

per person

Apr 8 - Apr 12

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Save 100% on your flight

Price was $1,327, price is now $858 per person

$858

per person

Feb 26 - Mar 3

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Casa Lefevre By Wynwood House

3.5 out of 5

Save 100% on your flight

Price was $3,779, price is now $2,496 per person

$2,496

per person

Mar 31 - Apr 7

found 10 hours ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this apartment in Las Cumbres. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions El Peñón and Summit Botanical Gardens & Zoo are located nearby.

Villa Botero By Casa Mojito B&B

3 out of 5

Price was $1,343, price is now $913 per person

$913

per person

Apr 2 - Apr 8

found 1 day ago

Roundtrip flight included

New York (JFK) to Panama City (PTY)

Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.

Casa Mallet by Wynwood House

4 out of 5

Save 100% on your flight

Price was $2,049, price is now $1,421 per person

$1,421

per person

Mar 31 - Apr 7

found 10 hours ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Las Americas Golden Tower Panama

4 out of 5

Price was $948, price is now $662 per person

$662

per person

Feb 26 - Mar 3

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.