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Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
  • 16 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.6/10 Excellent! (1,002 reviews)
This is an older property, and it shows, but it’s clean, the staff were incredibly helpful and knowledgeable. It’s a great location for proximity to restaurants and highway access. Nice pool area and fitness center. It was a great value for the money.

Reviewed on Apr 2, 2026

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
  • 14 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this family-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,001 reviews)
Yes the room were clean and everything was great to include the staff as they were very accommodating. The property was nice as well and everything was awesome. I have stayed here before and was happy I was able to do so again

Reviewed on Mar 30, 2026

Hilton Greenville
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
  • 14 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,127 reviews)
Clean room. Fresh breakfast. Great service!

Reviewed on Apr 1, 2026

Embassy Suites Greenville Golf Resort & Conference Center
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
  • 5 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (468 reviews)
Beautiful place

Reviewed on Mar 26, 2026

Grand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
  • 26 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (686 reviews)
Beautiful grounds

Reviewed on Apr 1, 2026

Hotel Hartness
Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

3 out of 5
10 Carolina Point Pkwy Greenville SC
  • 18 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,003 reviews)
Everything was awesome i really enjoyed myself

Reviewed on Apr 2, 2026

Drury Inn & Suites Greenville
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
  • 14 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,001 reviews)
Old building

Reviewed on Mar 30, 2026

Hyatt Place Greenville/Haywood
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
  • 6 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,001 reviews)
Property was clean for the most part. Lot of issues with people on the floors partying, but I think it was a special group that was in town for something. Had to call the front desk for security as we couldn’t sleep it almost 1 AM. But the staff was amazing. That’s for sure.

Reviewed on Mar 30, 2026

Hyatt Regency Greenville
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
  • 16 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,435 reviews)
Staff was great. Breakfast, too. The bed was a little soft (in both rooms) and hurt my back. Otherwise, an excellent stay.

Reviewed on Apr 1, 2026

Best Western Plus Greenville I-385 Inn & Suites
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street Greenville SC
  • 5 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9.2/10 Wonderful! (1,001 reviews)
Clean spacious room and great location.

Reviewed on Apr 1, 2026

Hyatt Place Greenville Downtown
Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown

3 out of 5
950 South Main Street Greenville SC
  • 4 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,001 reviews)
The coffee wasn’t good but everything else was great. Really really nice people. There was a glass coffee cup on a table on the third floor when the elevator door opened the entire time I stayed there which drove me nuts. I couldn’t believe no staff cleaned it up.

Reviewed on Apr 2, 2026

Homewood Suites by Hilton Greenville Downtown
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

3 out of 5
11 Ketron Court Greenville SC
  • 16 min drive from Prisma Health Greenville Memorial Hospital
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and ...
8.6/10 Excellent! (164 reviews)
Yes

Reviewed on Apr 1, 2026

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore Greenville

Looking for the very best last-minute deals on hotels in Greenville? Grabbing a last minute hotel deal in Greenville doesn't have to mean sacrificing quality. With a Hotwire Hot Rate, you can even save on 4-star accommodations!

Metropolitan cool and Southern hospitality merge seamlessly in Greenville, an easy-to-love city in the foothills of the Blue Ridge Mountains. The big draw downtown? A 60-foot waterfall that tumbles mightily – but oh so prettily – through the center of the action, just steps from an inviting line-up of shops, brewpubs, eateries and theaters.

Falls Park, which surrounds the waterfall and the Reedy River, makes for a soothing stroll. Snap a photo of the cascades from Liberty Bridge, a 355ft-long suspension bridge just downstream. From the park, shops stretch north along Main Street. With quotes emblazoned on the sidewalks and mice sculptures perched here and there (an ode to “Goodnight Moon”) this leafy street embraces whimsy to just the right degree.

Trails and waterfalls lure nature lovers to the foothills of the nearby Upcountry. The Cherokee called this region “The Great Blue Hills of God.” See if you agree on a hike to the summit of Table Rock Mountain, a beautiful spot for viewing the rolling landscape below - or popping the question.

Frequently Asked Questions About Greenville

When is the best time of the year to find Greenville hotel deals?

is the best time to find cheap Greenville hotel deals. You can find some great deals on hotel rates during the low seasons compared to the peak season.

When should I vacation to Greenville?

Vacations in Greenville are optimal during where the weather conditions are more favorable also are very popular times.

Where can I find the best last minute travel deals for Greenville?

Only on Hotwire you can find last minute hotel deals. Greenville offers over 669 properties with deals as low as $93. Also, take advantage of cheap deals on car rentals in Greenville.

What if I have to cancel my trip to Greenville?

The fastest path to canceling your booking is through one of our self-serve tools found at https://vacation.hotwire.com/lp/coronavirus-travel.