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Wise

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Wise Flights as Low as $289

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Fri, Sep 11 - Tue, Sep 22
PHL
Philadelphia Intl.
TRI
Tri-Cities Regional
$289 Roundtrip, found 15 hours ago
$289
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Fri, Sep 11 from Philadelphia Intl. to Tri-Cities Regional, returning Tue, Sep 22, priced at $289 found 15 hours ago
Delta
Tue, Sep 8 - Tue, Sep 15
JAX
Jacksonville Intl.
TRI
Tri-Cities Regional
$299 Roundtrip, found 14 hours ago
$299
Roundtrip
found 14 hours ago
Select Delta flight, departing Tue, Sep 8 from Jacksonville Intl. to Tri-Cities Regional, returning Tue, Sep 15, priced at $299 found 14 hours ago
Delta
Tue, Sep 8 - Tue, Sep 15
TPA
Tampa Intl.
TRI
Tri-Cities Regional
$299 Roundtrip, found 15 hours ago
$299
Roundtrip
found 15 hours ago
Select Delta flight, departing Tue, Sep 8 from Tampa Intl. to Tri-Cities Regional, returning Tue, Sep 15, priced at $299 found 15 hours ago
American Airlines
Sun, Sep 6 - Mon, Sep 14
TPA
Tampa Intl.
TRI
Tri-Cities Regional
$304 Roundtrip, found 14 hours ago
$304
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sun, Sep 6 from Tampa Intl. to Tri-Cities Regional, returning Mon, Sep 14, priced at $304 found 14 hours ago
American Airlines
Tue, Aug 4 - Sat, Aug 8
JAX
Jacksonville Intl.
TRI
Tri-Cities Regional
$306 Roundtrip, found 2 days ago
$306
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 4 from Jacksonville Intl. to Tri-Cities Regional, returning Sat, Aug 8, priced at $306 found 2 days ago
American Airlines
Fri, Sep 11 - Tue, Sep 22
TTN
Mercer
TRI
Tri-Cities Regional
$309 Roundtrip, found 3 days ago
$309
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Sep 11 from Mercer to Tri-Cities Regional, returning Tue, Sep 22, priced at $309 found 3 days ago
American Airlines
Fri, Sep 11 - Tue, Sep 22
PHL
Philadelphia Intl.
TRI
Tri-Cities Regional
$310 Roundtrip, found 15 hours ago
$310
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Fri, Sep 11 from Philadelphia Intl. to Tri-Cities Regional, returning Tue, Sep 22, priced at $310 found 15 hours ago
Delta
Sun, Sep 20 - Mon, Sep 28
RSW
Southwest Florida Intl.
TRI
Tri-Cities Regional
$319 Roundtrip, found 11 hours ago
$319
Roundtrip
found 11 hours ago
Select Delta flight, departing Sun, Sep 20 from Southwest Florida Intl. to Tri-Cities Regional, returning Mon, Sep 28, priced at $319 found 11 hours ago
Delta
Thu, Sep 3 - Fri, Sep 11
TPA
Tampa Intl.
TRI
Tri-Cities Regional
$319 Roundtrip, found 15 hours ago
$319
Roundtrip
found 15 hours ago
Select Delta flight, departing Thu, Sep 3 from Tampa Intl. to Tri-Cities Regional, returning Fri, Sep 11, priced at $319 found 15 hours ago
Delta
Sat, Jul 4 - Sat, Jul 4
MKE
General Mitchell Intl.
TRI
Tri-Cities Regional
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jul 4 from General Mitchell Intl. to Tri-Cities Regional, returning Sat, Jul 4, priced at $320 found 1 day ago
American Airlines
Tue, Aug 4 - Sat, Aug 8
JAX
Jacksonville Intl.
TRI
Tri-Cities Regional
$321 Roundtrip, found 2 days ago
$321
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 4 from Jacksonville Intl. to Tri-Cities Regional, returning Sat, Aug 8, priced at $321 found 2 days ago
Delta
Wed, Jul 8 - Tue, Jul 14
AUS
Austin-Bergstrom Intl.
TRI
Tri-Cities Regional
$326 Roundtrip, found 8 hours ago
$326
Roundtrip
found 8 hours ago
Select Delta flight, departing Wed, Jul 8 from Austin-Bergstrom Intl. to Tri-Cities Regional, returning Tue, Jul 14, priced at $326 found 8 hours ago
American Airlines
Sat, Jul 25 - Tue, Aug 4
PHX
Sky Harbor Intl.
TRI
Tri-Cities Regional
$357 Roundtrip, found 12 hours ago
$357
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jul 25 from Sky Harbor Intl. to Tri-Cities Regional, returning Tue, Aug 4, priced at $357 found 12 hours ago
American Airlines
Tue, Jul 14 - Thu, Jul 30
ACY
Atlantic City Intl.
TRI
Tri-Cities Regional
$375 Roundtrip, found 11 hours ago
$375
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Jul 14 from Atlantic City Intl. to Tri-Cities Regional, returning Thu, Jul 30, priced at $375 found 11 hours ago
Delta
Wed, Jun 17 - Thu, Jun 25
BDL
Bradley Intl.
TRI
Tri-Cities Regional
$386 Roundtrip, found 14 hours ago
$386
Roundtrip
found 14 hours ago
Select Delta flight, departing Wed, Jun 17 from Bradley Intl. to Tri-Cities Regional, returning Thu, Jun 25, priced at $386 found 14 hours ago
Breeze Airways
Sun, Jun 28 - Fri, Jul 17
ACY
Atlantic City Intl.
TRI
Tri-Cities Regional
$837 Roundtrip, found 11 hours ago
$837
Roundtrip
found 11 hours ago
Select Breeze Airways flight, departing Sun, Jun 28 from Atlantic City Intl. to Tri-Cities Regional, returning Fri, Jul 17, priced at $837 found 11 hours ago

Cheap Flights to Wise

Fall in love at first flight with your vacation to Wise by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Wise on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Wise, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Wise

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Wise with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TRI airport.

What is the cheapest month to fly to Wise?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Wise are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Wise?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Wise.

What airport is best to fly into Wise?

When you’re planning your trip to Wise, convenience is the name of the game. Luckily, Wise Tri-Cities Regional Airport is nearby so you can deplane and get going on checking off everything on your Wise must-do list.

How much are flights to Wise?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Wise on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $289, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Wise?

The trick to saving a stack of cash on your flight to Wise? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $289 right now, why wait?

Wise Flight Information
Destination airport
Tri-Cities Regional
Destination airport IATA code
TRI
Roundtrip price
$288

Last Minute Hotel Deals in Wise

The Inn at Wise

The Inn at Wise

3 out of 5
110 E Main Street Wise VA
Book a stay at this business-friendly hotel in Wise. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,000 reviews)
"Older facility upgrading to modern amenities. My sisters and I totally enjoyed staying and will return. Very safe secure facility even if staying alone. Beautiful old building, sweet southern hospitality."

Reviewed on Jun 7, 2026

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The Inn at Wise
Best Western Of Wise

Best Western Of Wise

2.5 out of 5
124 Woodland Drive SW Wise VA
Book a stay at this business-friendly hotel in Wise. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8/10 Very Good! (523 reviews)
"The staff was amazing the breakfast was great! The hotel was clean and comfortable! However we were hoping to go for a swim but the pool was out of order when we got there. Other than that we had a great time and the staff was very helpful. Great price also. The manager was helpful and very nice"

Reviewed on May 27, 2026

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Best Western Of Wise
Hampton Inn Norton, VA

Hampton Inn Norton, VA

2.5 out of 5
1051 Park Ave SW Norton VA
Stay at this hotel in Norton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions High Knob and Big Glades Community Square & Amphitheater ...
9.4/10 Exceptional! (176 reviews)
"Room was wonderful staff is very friendly they greet you every time you walk in very nice place to stay beautiful area"

Reviewed on Jun 10, 2026

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Hampton Inn Norton, VA
Quality Inn & Suites Big Stone Gap

Quality Inn & Suites Big Stone Gap

2.5 out of 5
4609 Aerial Way Big Stone Gap VA
Stay at this hotel in Big Stone Gap. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (512 reviews)
"Amazing place to stay! The property is so well kept and the staff is wonderful!"

Reviewed on Jun 7, 2026

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Quality Inn & Suites Big Stone Gap
Sleep Inn & Suites Clintwood

Sleep Inn & Suites Clintwood

2.5 out of 5
5625 Dickenson Hwy Clintwood VA
Book a stay at this business-friendly hotel in Clintwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (295 reviews)
"Wonderful stay, highly recommend! The staff was so friendly and helpful. The property, lobby and rooms were clean. The bed and pillows were probably the most comfy I have ever had in any hotel that I've stayed in. Absolutely wonderful stay!"

Reviewed on Jun 2, 2026

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Sleep Inn & Suites Clintwood
Western Front Hotel

Western Front Hotel

2.5 out of 5
3025 Fourth Ave. St. Paul VA
Stay at this hotel in St. Paul. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (329 reviews)
"Loved our stay. Comfortable and easy. Used the fire pit out back for a relaxing night of moon and stargazing. Breakfast was perfect and the trip was great with the Clinch River Days Festival."

Reviewed on Jun 4, 2026

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Western Front Hotel
Days Inn by Wyndham Norton

Days Inn by Wyndham Norton

2 out of 5
375 Wharton Ln Ne Norton VA
Stay at this hotel in Norton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions High Knob and Big Glades Community Square & Amphitheater ...
7/10 Good! (359 reviews)
"Breakfast was good for the money but not much there. Room was great. Clean. Comfortable and updated. Great value for the money for sure!!"

Reviewed on May 24, 2026

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Days Inn by Wyndham Norton
Econo Lodge Inn & Suites Norton - Wise South

Econo Lodge Inn & Suites Norton - Wise South

2 out of 5
551 Highway 58 E Norton VA
Stay at this hotel in Norton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
6.6/10 (350 reviews)
"Room was dirty the hair dry didn't work and way to many hidden charges"

Reviewed on Jun 10, 2026

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Econo Lodge Inn & Suites Norton - Wise South
See all 35 properties in Wise
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.