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Tupelo

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Tupelo Flights as Low as $441

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$441 Roundtrip, found 6 days ago
$441
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $441 found 6 days ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$463 Roundtrip, found 6 days ago
$463
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $463 found 6 days ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$493 Roundtrip, found 6 days ago
$493
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $493 found 6 days ago
United
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$498 Roundtrip, found 6 days ago
$498
Roundtrip
found 6 days ago
Select United flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $498 found 6 days ago
American Airlines
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$545 Roundtrip, found 13 hours ago
$545
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $545 found 13 hours ago
United
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$550 Roundtrip, found 6 days ago
$550
Roundtrip
found 6 days ago
Select United flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $550 found 6 days ago
American Airlines
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$566 Roundtrip, found 13 hours ago
$566
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $566 found 13 hours ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$575 Roundtrip, found 6 days ago
$575
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $575 found 6 days ago
United
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$578 Roundtrip, found 6 days ago
$578
Roundtrip
found 6 days ago
Select United flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $578 found 6 days ago
United
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$596 Roundtrip, found 6 days ago
$596
Roundtrip
found 6 days ago
Select United flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $596 found 6 days ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$597 Roundtrip, found 6 days ago
$597
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $597 found 6 days ago
American Airlines
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$597 Roundtrip, found 13 hours ago
$597
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $597 found 13 hours ago
American Airlines
Wed, Jun 24 - Wed, Jul 1
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$605 Roundtrip, found 9 hours ago
$605
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Wed, Jul 1, priced at $605 found 9 hours ago
United
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$607 Roundtrip, found 6 days ago
$607
Roundtrip
found 6 days ago
Select United flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $607 found 6 days ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$613 Roundtrip, found 2 days ago
$613
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $613 found 2 days ago
American Airlines
Tue, Jun 16 - Tue, Jun 23
LAX
Los Angeles Intl.
TUP
Tupelo Regional
$694 Roundtrip, found 2 days ago
$694
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 16 from Los Angeles Intl. to Tupelo Regional, returning Tue, Jun 23, priced at $694 found 2 days ago

Cheap Flights to Tupelo

Fall in love at first flight with your vacation to Tupelo by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Tupelo on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Tupelo, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Tupelo

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Tupelo with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TUP airport.

What is the cheapest month to fly to Tupelo?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Tupelo are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Tupelo?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Tupelo.

What airport is best to fly into Tupelo?

When you’re planning your trip to Tupelo, convenience is the name of the game. Luckily, Tupelo Tupelo Regional Airport is nearby so you can deplane and get going on checking off everything on your Tupelo must-do list.

How much are flights to Tupelo?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Tupelo on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $441, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Tupelo?

The trick to saving a stack of cash on your flight to Tupelo? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $441 right now, why wait?

Tupelo Flight Information
Destination airport
Tupelo
Destination airport IATA code
TUP

Last Minute Hotel Deals in Tupelo

Best Western Plus Tupelo Inn & Suites

Best Western Plus Tupelo Inn & Suites

2.5 out of 5
3158 N Gloster Street Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,018 reviews)
"Staff"

Reviewed on Jun 7, 2026

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Best Western Plus Tupelo Inn & Suites
La Quinta Inn & Suites by Wyndham Tupelo

La Quinta Inn & Suites by Wyndham Tupelo

3 out of 5
1013 N Gloster St Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,022 reviews)
"I the ice machine on the 1st floor didn't work. I stayed there 2 different time in the past week. The light didn't work when you come in the room. I talked to the manager and he could care less! Won't stay there again. I didn't get my wake up call."

Reviewed on Jun 9, 2026

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La Quinta Inn & Suites by Wyndham Tupelo
Baymont by Wyndham Tupelo

Baymont by Wyndham Tupelo

2.5 out of 5
625 Spicer Drive Tupelo MS
Book a stay at this business-friendly motel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,001 reviews)
"We asked that our room NOT be cleaned but each day they came in anyway. Free breakfast means coffee, juice, cereal, toast, waffles, an apple or if your lucky a banana. I would return there because of the staff."

Reviewed on Jun 7, 2026

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Baymont by Wyndham Tupelo
Red Roof Inn Tupelo

Red Roof Inn Tupelo

2 out of 5
1516 Mccullough Blvd Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,007 reviews)
"Very convenient and reasonably priced. Room was spacious and clean. Bed comfortable. It was a very pleasant stay. Looking forward to being there again soon."

Reviewed on Jun 10, 2026

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Red Roof Inn Tupelo
Spark by Hilton Tupelo

Spark by Hilton Tupelo

2.5 out of 5
186 Stone Creek Blvd Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,000 reviews)
"The room was very musty/moldy and made me as soon as I walked in and worse overnight. Too booked to change rooms."

Reviewed on Jun 8, 2026

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Spark by Hilton Tupelo
Hotel Tupelo, a Wyndham Hotel

Hotel Tupelo, a Wyndham Hotel

3 out of 5
314 EAST MAIN ST Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (651 reviews)
"Love staying here any chance im in the area. Such a fun and boutique style accommodations. Love the restaurant as well!"

Reviewed on Jun 3, 2026

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Hotel Tupelo, a Wyndham Hotel
Holiday Inn Express Hotel & Suites Tupelo by IHG

Holiday Inn Express Hotel & Suites Tupelo by IHG

2.5 out of 5
1612 Mcclure Cove Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,006 reviews)
"Very friendly and a great breakfast."

Reviewed on Jun 9, 2026

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Holiday Inn Express Hotel & Suites Tupelo by IHG
Tru By Hilton Tupelo

Tru By Hilton Tupelo

2.5 out of 5
1003 Landmark Blvd Tupelo MS
Stay at this hotel in Tupelo. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.2/10 Wonderful! (732 reviews)
"Asked for a room away from the elevator and she said there were no rooms available with a king bed. Never had that problem in any other hotel my husband and I have stayed in. It was not a late check-in."

Reviewed on May 29, 2026

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Tru By Hilton Tupelo
See all 1,049 properties in Tupelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Candlewood Suites Tupelo North by IHG

Candlewood Suites Tupelo North by IHG

2.5 out of 5
979 North Gloster St Street Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (458 reviews)
"The room was very nice and spacious and we had no complaints with the staff whatsoever"

Reviewed on Jun 1, 2026

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Candlewood Suites Tupelo North by IHG
Holiday Inn Hotel & Suites Tupelo North by IHG

Holiday Inn Hotel & Suites Tupelo North by IHG

3 out of 5
923 North Gloster Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,005 reviews)
"Staff were very helpful and friendly. The rooms were large and spacious also."

Reviewed on Jun 9, 2026

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Holiday Inn Hotel & Suites Tupelo North by IHG
See all 1,049 properties in Tupelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.