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Tupelo

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Tupelo Flights as Low as $254

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Aug 5 - Tue, Aug 12
ORD
O'Hare Intl.
TUP
Tupelo Regional
$254 Roundtrip, found 2 days ago
$254
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Tue, Aug 12, priced at $254 found 2 days ago
American Airlines
Mon, Aug 4 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$266 Roundtrip, found 3 days ago
$266
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 4 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $266 found 3 days ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$272 Roundtrip, found 5 days ago
$272
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $272 found 5 days ago
American Airlines
Tue, Aug 5 - Fri, Aug 8
ORD
O'Hare Intl.
TUP
Tupelo Regional
$276 Roundtrip, found 2 days ago
$276
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Fri, Aug 8, priced at $276 found 2 days ago
American Airlines
Sat, Aug 2 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$284 Roundtrip, found 5 days ago
$284
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Aug 2 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $284 found 5 days ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$300 Roundtrip, found 2 days ago
$300
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $300 found 2 days ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$307 Roundtrip, found 4 hours ago
$307
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $307 found 4 hours ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$309 Roundtrip, found 2 days ago
$309
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $309 found 2 days ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$311 Roundtrip, found 4 hours ago
$311
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $311 found 4 hours ago
American Airlines
Mon, Aug 4 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$315 Roundtrip, found 12 hours ago
$315
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Aug 4 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $315 found 12 hours ago
American Airlines
Wed, Aug 6 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$319 Roundtrip, found 4 days ago
$319
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 6 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $319 found 4 days ago
American Airlines
Tue, Aug 5 - Fri, Aug 8
ORD
O'Hare Intl.
TUP
Tupelo Regional
$320 Roundtrip, found 8 hours ago
$320
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Fri, Aug 8, priced at $320 found 8 hours ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$322 Roundtrip, found 5 days ago
$322
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $322 found 5 days ago
Contour Airlines
Wed, Aug 6 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$323 Roundtrip, found 4 days ago
$323
Roundtrip
found 4 days ago
Select Contour Airlines flight, departing Wed, Aug 6 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $323 found 4 days ago
American Airlines
Wed, Aug 6 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$331 Roundtrip, found 6 days ago
$331
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Aug 6 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $331 found 6 days ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$333 Roundtrip, found 5 days ago
$333
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $333 found 5 days ago

Cheap Flights to Tupelo

Fall in love at first flight with your vacation to Tupelo by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Tupelo on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Tupelo, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Tupelo

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Tupelo with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TUP airport.

What is the cheapest month to fly to Tupelo?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Tupelo are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Tupelo?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Tupelo.

What airport is best to fly into Tupelo?

When you’re planning your trip to Tupelo, convenience is the name of the game. Luckily, Tupelo Tupelo Regional Airport is nearby so you can deplane and get going on checking off everything on your Tupelo must-do list.

How much are flights to Tupelo?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Tupelo on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $254, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Tupelo?

The trick to saving a stack of cash on your flight to Tupelo? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $254 right now, why wait?

Tupelo Flight Information
Destination airport
Tupelo Regional
Destination airport IATA code
TUP
Roundtrip price
$395

Last Minute Hotel Deals in Tupelo

Baymont by Wyndham Tupelo
Baymont by Wyndham Tupelo
2.5 out of 5
625 Spicer Drive, Tupelo, MS
Book a stay at this business-friendly motel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (909 reviews)
"Lovely think they should sale alcohol beverages.. and I don’t like the amount of people that can be in the room What if I’m a single parent with 2kids I have to pay for double beds when we can all sleep in one I think that should be advices"

Reviewed on Jul 11, 2025

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Baymont by Wyndham Tupelo
Red Roof Inn Tupelo
Red Roof Inn Tupelo
2 out of 5
1516 Mccullough Blvd, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,001 reviews)
"Clean and secure. Quiet"

Reviewed on Jul 8, 2025

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Red Roof Inn Tupelo
La Quinta Inn & Suites by Wyndham Tupelo
La Quinta Inn & Suites by Wyndham Tupelo
3 out of 5
1013 N Gloster St, Tupelo, MS
Stay at this 3-star business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,004 reviews)
"Todo excelente, volvería a estar ahí"

Reviewed on Jul 9, 2025

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La Quinta Inn & Suites by Wyndham Tupelo
Best Western Plus Tupelo Inn & Suites
Best Western Plus Tupelo Inn & Suites
2.5 out of 5
3158 N Gloster Street, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,006 reviews)
"everything was good."

Reviewed on Jul 9, 2025

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Best Western Plus Tupelo Inn & Suites
Holiday Inn Express Hotel & Suites Tupelo by IHG
Holiday Inn Express Hotel & Suites Tupelo by IHG
2.5 out of 5
1612 Mcclure Cove, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"Clean. Close to good dining. Staff was very polite."

Reviewed on Jul 8, 2025

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Holiday Inn Express Hotel & Suites Tupelo by IHG
Tru By Hilton Tupelo
Tru By Hilton Tupelo
2.5 out of 5
1003 Landmark Blvd, Tupelo, MS
Stay at this hotel in Tupelo. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.2/10 Wonderful! (521 reviews)
"First time at a Tru Hotel and will not be the last. Has everything you need, clean, friendly staff at a fair price."

Reviewed on Jul 10, 2025

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Tru By Hilton Tupelo
Hotel Tupelo, a Wyndham Hotel
Hotel Tupelo, a Wyndham Hotel
3 out of 5
314 EAST MAIN ST, Tupelo, MS
Stay at this 3-star business-friendly hotel in Tupelo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (515 reviews)
"This was such a cute hotel. So glad we stayed here"

Reviewed on Jul 10, 2025

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Hotel Tupelo, a Wyndham Hotel
Comfort Inn
Comfort Inn
2.5 out of 5
1532 Mccullough Blvd, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (938 reviews)
"Nice property and breakfast. The bathtub didn’t have a plug and they couldn’t find one. The next night when I asked for a working tub they put us in a room with only a shower. I cannot stand in a shower. Moved to another motel 3rd night."

Reviewed on Jul 10, 2025

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Comfort Inn
See all 895 properties in Tupelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Candlewood Suites Tupelo North by IHG
Candlewood Suites Tupelo North by IHG
2.5 out of 5
979 North Gloster St Street, and Mccullough Boulevard, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the helpful staff in our ...
8.4/10 Very Good! (401 reviews)
Nice hotel
"Nice hotel. Clean room. Friendly staff. Will be back again soon."

Reviewed on Jul 6, 2025

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Candlewood Suites Tupelo North by IHG
Holiday Inn Hotel & Suites Tupelo North by IHG
Holiday Inn Hotel & Suites Tupelo North by IHG
3 out of 5
923 North Gloster, Tupelo, MS
Stay at this 3-star business-friendly hotel in Tupelo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (952 reviews)
"Staff were professional and accommodated me well during check in."

Reviewed on Jul 6, 2025

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Holiday Inn Hotel & Suites Tupelo North by IHG
See all 895 properties in Tupelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.