Search Cheap Flights to
Seffner

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Seffner Flights as Low as $166

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, May 9 - Sat, May 16
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$166 Roundtrip, found 4 hours ago
$166
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, May 9 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Sat, May 16, priced at $166 found 4 hours ago
Frontier Airlines
Mon, Apr 20 - Thu, Apr 30
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$176 Roundtrip, found 2 hours ago
$176
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Mon, Apr 20 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Thu, Apr 30, priced at $176 found 2 hours ago
Sun Country Airlines
Sun, May 10 - Thu, May 14
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$179 Roundtrip, found 6 hours ago
$179
Roundtrip
found 6 hours ago
Select Sun Country Airlines flight, departing Sun, May 10 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Thu, May 14, priced at $179 found 6 hours ago
Frontier Airlines
Sat, May 9 - Sat, May 16
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$190 Roundtrip, found 4 hours ago
$190
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, May 9 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Sat, May 16, priced at $190 found 4 hours ago
Sun Country Airlines
Mon, May 11 - Fri, May 15
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$193 Roundtrip, found 1 day ago
$193
Roundtrip
found 1 day ago
Select Sun Country Airlines flight, departing Mon, May 11 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Fri, May 15, priced at $193 found 1 day ago
Frontier Airlines
Sat, May 9 - Sat, May 16
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$195 Roundtrip, found 4 hours ago
$195
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, May 9 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Sat, May 16, priced at $195 found 4 hours ago
Frontier Airlines
Wed, May 13 - Fri, May 15
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$199 Roundtrip, found 6 hours ago
$199
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Wed, May 13 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Fri, May 15, priced at $199 found 6 hours ago
Frontier Airlines
Thu, Apr 23 - Thu, Apr 30
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$203 Roundtrip, found 2 hours ago
$203
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Thu, Apr 23 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Thu, Apr 30, priced at $203 found 2 hours ago
Sun Country Airlines
Sun, May 10 - Thu, May 14
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$203 Roundtrip, found 6 hours ago
$203
Roundtrip
found 6 hours ago
Select Sun Country Airlines flight, departing Sun, May 10 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Thu, May 14, priced at $203 found 6 hours ago
Frontier Airlines
Wed, May 13 - Fri, May 15
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$205 Roundtrip, found 6 hours ago
$205
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Wed, May 13 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Fri, May 15, priced at $205 found 6 hours ago
Sun Country Airlines
Mon, Apr 13 - Thu, Apr 23
MSP
Minneapolis - St. Paul Intl.
PIE
St. Petersburg-Clearwater Intl.
$207 Roundtrip, found 13 hours ago
$207
Roundtrip
found 13 hours ago
Select Sun Country Airlines flight, departing Mon, Apr 13 from Minneapolis - St. Paul Intl. to St. Petersburg-Clearwater Intl., returning Thu, Apr 23, priced at $207 found 13 hours ago
Sun Country Airlines
Sun, Jul 19 - Mon, Jul 27
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$207 Roundtrip, found 11 hours ago
$207
Roundtrip
found 11 hours ago
Select Sun Country Airlines flight, departing Sun, Jul 19 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Mon, Jul 27, priced at $207 found 11 hours ago
Delta
Sat, Aug 29 - Sat, Sep 12
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$219 Roundtrip, found 5 hours ago
$219
Roundtrip
found 5 hours ago
Select Delta flight, departing Sat, Aug 29 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Sat, Sep 12, priced at $219 found 5 hours ago
United
Sat, Aug 29 - Sat, Sep 12
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$239 Roundtrip, found 5 hours ago
$239
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Aug 29 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Sat, Sep 12, priced at $239 found 5 hours ago
American Airlines
Sat, Aug 29 - Sat, Sep 12
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$239 Roundtrip, found 5 hours ago
$239
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Aug 29 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Sat, Sep 12, priced at $239 found 5 hours ago
Alaska Airlines
Sun, Jul 19 - Mon, Jul 27
MSP
Minneapolis - St. Paul Intl.
TPA
Tampa Intl.
$848 Roundtrip, found 11 hours ago
$848
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Sun, Jul 19 from Minneapolis - St. Paul Intl. to Tampa Intl., returning Mon, Jul 27, priced at $848 found 11 hours ago

Cheap Flights to Seffner

Fall in love at first flight with your vacation to Seffner by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seffner on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seffner, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seffner

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seffner with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TPA airport.

What is the cheapest month to fly to Seffner?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seffner are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seffner?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Seffner.

What airport is best to fly into Seffner?

When you’re planning your trip to Seffner, convenience is the name of the game. Luckily, Seffner Peter O. Knight Airport is nearby so you can deplane and get going on checking off everything on your Seffner must-do list.

How much are flights to Seffner?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seffner on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $166, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seffner?

The trick to saving a stack of cash on your flight to Seffner? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $166 right now, why wait?

Seffner Flight Information
Destination airport
Tampa Intl.
Destination airport IATA code
TPA
Roundtrip price
$165

Last Minute Hotel Deals in Seffner

Hotel Tampa Riverwalk

Hotel Tampa Riverwalk

4 out of 5
200 N Ashley Dr Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy 2 bars/lounges, breakfast (surcharge), and a fitness center. Our guests praise the pool and the helpful ...
7.2/10 Good! (1,816 reviews)
Great

Reviewed on Mar 30, 2026

Get rates
Hotel Tampa Riverwalk
Ramada by Wyndham Tampa Westshore Airport South

Ramada by Wyndham Tampa Westshore Airport South

3 out of 5
1200 N Westshore Blvd Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.2/10 (4,226 reviews)
Advertised as restaurant and lounge but neither was open! Didn't want to accommodate me to another floor! Was put on 5 th Floor

Reviewed on Mar 30, 2026

Get rates
Ramada by Wyndham Tampa Westshore Airport South
Sailport Waterfront Suites

Sailport Waterfront Suites

3.5 out of 5
2506 N Rocky Point Dr Tampa FL
Book a stay at this business-friendly aparthotel in Tampa. Enjoy breakfast (surcharge), a fitness center, and a 24-hour front desk. Our guests praise the pool ...
8.4/10 Very Good! (4,975 reviews)
Everything was amazing

Reviewed on Mar 27, 2026

Get rates
Sailport Waterfront Suites
The Westin Tampa Bay

The Westin Tampa Bay

4 out of 5
7627 W Courtney Campbell Cswy Tampa FL
Book a stay at this beach hotel in Tampa. Enjoy free WiFi, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,199 reviews)
Giod

Reviewed on Mar 30, 2026

Get rates
The Westin Tampa Bay
Grand Hyatt Tampa Bay

Grand Hyatt Tampa Bay

4 out of 5
2900 Bayport Drive Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,218 reviews)
I’ve stayed here multiple times. This place is always clean and the staff is always accommodating. The only issue I have ever had is with the pay for parking. My room key wouldn’t let me out the gate and I had to call for help which was resolved quickly.

Reviewed on Mar 24, 2026

Get rates
Grand Hyatt Tampa Bay
BAY INN

BAY INN

2 out of 5
2307 E BUSCH BLVD Tampa FL
Stay at this motel in Tampa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Busch Gardens Tampa Bay and Seminole Hard Rock Casino ...
6/10 (405 reviews)
The location does not seem to be the safest. We were there for one night due to a work event, and he was the only available place near where we need to be. The first room we got was on the second floor, next to a room that was occupied and had the family members speaking on the phone on speaker, ...

Reviewed on Mar 30, 2026

Get rates
BAY INN
La Quinta Inn by Wyndham Tampa Near Busch Gardens

La Quinta Inn by Wyndham Tampa Near Busch Gardens

3 out of 5
9202 N 30th St Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
7.4/10 Good! (2,881 reviews)
Breakfast poor

Reviewed on Mar 30, 2026

Get rates
La Quinta Inn by Wyndham Tampa Near Busch Gardens
HomeTowne Studios by Red Roof Tampa - Airport

HomeTowne Studios by Red Roof Tampa - Airport

2 out of 5
6121 West Sitka Street Tampa FL
Stay at this hotel in Tampa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Raymond James Stadium and George M. Steinbrenner Field ...
8.6/10 Excellent! (967 reviews)
While the furnishings were spartan, the room was squeeky clean, organized well and provded everything we needed. I felt safe here, and the 9 minute commute to the airport can't be beat. The beds were comfortable, the kitchentte had a small refrigerator/freezer, 2 electric infared burners, and a microwave. ...

Reviewed on Mar 30, 2026

Get rates
HomeTowne Studios by Red Roof Tampa - Airport
See all 4,861 properties in Seffner
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.