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Mexico

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Mexico Flights as Low as $298

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Thu, Apr 16 - Tue, Apr 21
BNA
Nashville Intl.
COU
Columbia Regional
$298 Roundtrip, found 8 hours ago
$298
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Apr 16 from Nashville Intl. to Columbia Regional, returning Tue, Apr 21, priced at $298 found 8 hours ago
United
Thu, Apr 16 - Tue, Apr 21
BNA
Nashville Intl.
COU
Columbia Regional
$298 Roundtrip, found 8 hours ago
$298
Roundtrip
found 8 hours ago
Select United flight, departing Thu, Apr 16 from Nashville Intl. to Columbia Regional, returning Tue, Apr 21, priced at $298 found 8 hours ago
United
Tue, Jun 2 - Tue, Jun 16
DAY
James M. Cox Dayton Intl.
COU
Columbia Regional
$303 Roundtrip, found 1 day ago
$303
Roundtrip
found 1 day ago
Select United flight, departing Tue, Jun 2 from James M. Cox Dayton Intl. to Columbia Regional, returning Tue, Jun 16, priced at $303 found 1 day ago
American Airlines
Tue, Apr 14 - Sat, Apr 18
BNA
Nashville Intl.
COU
Columbia Regional
$316 Roundtrip, found 4 hours ago
$316
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Apr 14 from Nashville Intl. to Columbia Regional, returning Sat, Apr 18, priced at $316 found 4 hours ago
United
Tue, Jun 2 - Tue, Jun 16
DAY
James M. Cox Dayton Intl.
COU
Columbia Regional
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select United flight, departing Tue, Jun 2 from James M. Cox Dayton Intl. to Columbia Regional, returning Tue, Jun 16, priced at $319 found 1 day ago
United
Tue, Jun 2 - Tue, Jun 16
DAY
James M. Cox Dayton Intl.
COU
Columbia Regional
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select United flight, departing Tue, Jun 2 from James M. Cox Dayton Intl. to Columbia Regional, returning Tue, Jun 16, priced at $320 found 1 day ago
United
Sat, Jun 20 - Thu, Jun 25
LGA
LaGuardia
COU
Columbia Regional
$328 Roundtrip, found 18 hours ago
$328
Roundtrip
found 18 hours ago
Select United flight, departing Sat, Jun 20 from LaGuardia to Columbia Regional, returning Thu, Jun 25, priced at $328 found 18 hours ago
American Airlines
Wed, Jun 3 - Thu, Jun 18
LGA
LaGuardia
COU
Columbia Regional
$334 Roundtrip, found 13 hours ago
$334
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jun 3 from LaGuardia to Columbia Regional, returning Thu, Jun 18, priced at $334 found 13 hours ago
American Airlines
Tue, May 5 - Tue, May 12
DFW
Dallas-Fort Worth Intl.
COU
Columbia Regional
$386 Roundtrip, found 12 hours ago
$386
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Tue, May 5 from Dallas-Fort Worth Intl. to Columbia Regional, returning Tue, May 12, priced at $386 found 12 hours ago
United
Wed, Apr 1 - Sun, Apr 5
ATL
Hartsfield-Jackson Atlanta Intl.
COU
Columbia Regional
$405 Roundtrip, found 23 hours ago
$405
Roundtrip
found 23 hours ago
Select United flight, departing Wed, Apr 1 from Hartsfield-Jackson Atlanta Intl. to Columbia Regional, returning Sun, Apr 5, priced at $405 found 23 hours ago
United
Thu, Apr 2 - Mon, Apr 6
PIT
Pittsburgh Intl.
COU
Columbia Regional
$405 Roundtrip, found 16 hours ago
$405
Roundtrip
found 16 hours ago
Select United flight, departing Thu, Apr 2 from Pittsburgh Intl. to Columbia Regional, returning Mon, Apr 6, priced at $405 found 16 hours ago
United
Sun, Jun 21 - Sat, Jun 27
EWR
Newark Liberty Intl. Airport
COU
Columbia Regional
$419 Roundtrip, found 1 day ago
$419
Roundtrip
found 1 day ago
Select United flight, departing Sun, Jun 21 from Newark Liberty Intl. Airport to Columbia Regional, returning Sat, Jun 27, priced at $419 found 1 day ago
American Airlines
Sat, May 9 - Tue, May 26
SNA
John Wayne
COU
Columbia Regional
$432 Roundtrip, found 18 hours ago
$432
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, May 9 from John Wayne to Columbia Regional, returning Tue, May 26, priced at $432 found 18 hours ago
American Airlines
Tue, May 5 - Tue, May 12
DFW
Dallas-Fort Worth Intl.
COU
Columbia Regional
$437 Roundtrip, found 12 hours ago
$437
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Tue, May 5 from Dallas-Fort Worth Intl. to Columbia Regional, returning Tue, May 12, priced at $437 found 12 hours ago
American Airlines
Sun, Jun 21 - Sat, Jun 27
JFK
John F. Kennedy Intl.
COU
Columbia Regional
$545 Roundtrip, found 5 days ago
$545
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Jun 21 from John F. Kennedy Intl. to Columbia Regional, returning Sat, Jun 27, priced at $545 found 5 days ago
American Airlines
Fri, Mar 27 - Sat, Mar 28
TLH
Tallahassee Intl.
COU
Columbia Regional
$633 Roundtrip, found 18 hours ago
$633
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Mar 27 from Tallahassee Intl. to Columbia Regional, returning Sat, Mar 28, priced at $633 found 18 hours ago

Cheap Flights to Mexico

Fall in love at first flight with your vacation to Mexico by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mexico on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mexico, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mexico

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mexico with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the COU airport.

What is the cheapest month to fly to Mexico?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mexico are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mexico?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mexico.

What airport is best to fly into Mexico?

When you’re planning your trip to Mexico, convenience is the name of the game. Luckily, Mexico Columbia Regional Airport is nearby so you can deplane and get going on checking off everything on your Mexico must-do list.

How much are flights to Mexico?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mexico on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $298, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mexico?

The trick to saving a stack of cash on your flight to Mexico? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $298 right now, why wait?

Mexico Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$298

Last Minute Hotel Deals in Mexico

Best Western Teal Lake Inn

Best Western Teal Lake Inn

2.5 out of 5
3602 S Clark St Mexico MO
Book a stay at this business-friendly hotel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (504 reviews)
Room was very clean and quiet

Reviewed on Mar 15, 2026

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Best Western Teal Lake Inn
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

2.5 out of 5
900 Vance Rd Mexico MO
Book a stay at this business-friendly motel in Mexico. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Green Estates and Teal Lake Park ...
5.6/10 (392 reviews)
survice sucked\

Reviewed on Mar 1, 2026

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Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico

2 out of 5
2902 S. Clark Mexico MO
Stay at this hotel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Green Estates and Lakeview Park are located nearby.
7/10 Good! (299 reviews)
It was ok. Seemed clean but the towels appeared to be dirty at be least a couple of them. Not worth the money but ok for one night. Stayed at a super 8 in much better condition for a little over half the price.

Reviewed on Mar 22, 2026

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Days Inn by Wyndham Mexico
Budget Inn Mexico MO on US 54

Budget Inn Mexico MO on US 54

2 out of 5
1010 E Liberty St Mexico MO
Book a stay at this business-friendly motel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Popular attractions MLK Jr. Park and Garfield Park ...
7/10 Good! (111 reviews)
The front door was locked with a note that said, will be back at 6:00 PM. That was at 1:30 the day of a funeral I needed to be at , at 2:00. I wanted to shower and get dressed by 2:00. I had to change outside in a parking lot behind a dumpster down the road. When I called to cancel my reservation ...

Reviewed on Jan 12, 2026

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Budget Inn Mexico MO on US 54
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,757 reviews)
Very clean as always

Reviewed on Mar 22, 2026

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Country Inn & Suites by Radisson, Columbia, MO
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,393 reviews)
Room mostly clean | Very minimal in room amenities, was just shampoo, conditioner, body wash, and a bar of soap. Was disappointing for such an expensive and highly rated room | Check in staff were very friendly and kind. Even had popcorn for us to take to the room | Breakfast was wonderful and had ...

Reviewed on Mar 25, 2026

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Drury Plaza Hotel Columbia East
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,268 reviews)
Our room smelled like a wet dog and stinky feet. When i booked the room, i booked a double queen room but we got a king and a pull out couch room. We did not get pillows for the pull out couch. The pool was so cold my kids did not want to swim.

Reviewed on Mar 23, 2026

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Best Western Plus Columbia Inn
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,226 reviews)
Great place to stay for a reasonable cost. Clean, friendly staff and comfy beds!

Reviewed on Mar 24, 2026

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Wingate by Wyndham - Columbia
See all 211 properties in Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.