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Grimes

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Grimes Flights as Low as $88

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Mar 17 - Fri, Mar 20
MCO
Orlando Intl.
DSM
Des Moines Intl.
$88 Roundtrip, found 1 day ago
$88
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Mar 17 from Orlando Intl. to Des Moines Intl., returning Fri, Mar 20, priced at $88 found 1 day ago
Frontier Airlines
Wed, Mar 25 - Mon, Mar 30
DEN
Denver Intl.
DSM
Des Moines Intl.
$120 Roundtrip, found 1 day ago
$120
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Mar 25 from Denver Intl. to Des Moines Intl., returning Mon, Mar 30, priced at $120 found 1 day ago
American Airlines
Fri, Apr 17 - Mon, Apr 20
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$174 Roundtrip, found 1 day ago
$174
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Apr 17 from George Bush Intercontinental to Des Moines Intl., returning Mon, Apr 20, priced at $174 found 1 day ago
Frontier Airlines
Mon, Apr 13 - Fri, Apr 24
SAN
San Diego Intl.
DSM
Des Moines Intl.
$210 Roundtrip, found 23 hours ago
$210
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Mon, Apr 13 from San Diego Intl. to Des Moines Intl., returning Fri, Apr 24, priced at $210 found 23 hours ago
Frontier Airlines
Mon, Apr 13 - Mon, Apr 20
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$211 Roundtrip, found 8 hours ago
$211
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Mon, Apr 13 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Mon, Apr 20, priced at $211 found 8 hours ago
Frontier Airlines
Fri, Apr 3 - Mon, Apr 20
AUS
Austin-Bergstrom Intl.
DSM
Des Moines Intl.
$218 Roundtrip, found 22 hours ago
$218
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Fri, Apr 3 from Austin-Bergstrom Intl. to Des Moines Intl., returning Mon, Apr 20, priced at $218 found 22 hours ago
Frontier Airlines
Fri, Mar 13 - Sat, Mar 21
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$220 Roundtrip, found 3 hours ago
$220
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Fri, Mar 13 from Sky Harbor Intl. to Des Moines Intl., returning Sat, Mar 21, priced at $220 found 3 hours ago
Frontier Airlines
Fri, Apr 3 - Mon, Apr 20
DTW
Detroit Metropolitan Wayne County
DSM
Des Moines Intl.
$231 Roundtrip, found 4 days ago
$231
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Apr 3 from Detroit Metropolitan Wayne County to Des Moines Intl., returning Mon, Apr 20, priced at $231 found 4 days ago
Bargain Flight
Tue, Mar 31 - Tue, Apr 7
MEM
Memphis Intl.
DSM
Des Moines Intl.
$235 Roundtrip, found 1 day ago
$235
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Mar 31 from Memphis Intl. to Des Moines Intl., returning Tue, Apr 7, priced at $235 found 1 day ago
Frontier Airlines
Sat, Mar 14 - Wed, Mar 25
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$246 Roundtrip, found 3 days ago
$246
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Mar 14 from Charlotte-Douglas Intl. to Des Moines Intl., returning Wed, Mar 25, priced at $246 found 3 days ago
United
Wed, Jun 24 - Sat, Jul 4
GUC
Gunnison-Crested Butte Regional
DSM
Des Moines Intl.
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select United flight, departing Wed, Jun 24 from Gunnison-Crested Butte Regional to Des Moines Intl., returning Sat, Jul 4, priced at $251 found 1 day ago
Bargain Flight
Sat, Mar 14 - Tue, Mar 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$255 Roundtrip, found 21 hours ago
$255
Roundtrip
found 21 hours ago
Select Bargain Flight flight, departing Sat, Mar 14 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $255 found 21 hours ago
Bargain Flight
Wed, Mar 25 - Tue, Apr 7
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Wed, Mar 25 from Los Angeles Intl. to Des Moines Intl., returning Tue, Apr 7, priced at $257 found 1 day ago
Bargain Flight
Sat, May 2 - Sat, May 9
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$280 Roundtrip, found 1 day ago
$280
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, May 2 from McClellan-Palomar to Des Moines Intl., returning Sat, May 9, priced at $280 found 1 day ago
United
Wed, Apr 1 - Mon, Apr 6
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$306 Roundtrip, found 6 days ago
$306
Roundtrip
found 6 days ago
Select United flight, departing Wed, Apr 1 from Newark Liberty Intl. Airport to Des Moines Intl., returning Mon, Apr 6, priced at $306 found 6 days ago
American Airlines
Tue, Jun 16 - Tue, Jun 23
LGA
LaGuardia
DSM
Des Moines Intl.
$325 Roundtrip, found 20 hours ago
$325
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jun 16 from LaGuardia to Des Moines Intl., returning Tue, Jun 23, priced at $325 found 20 hours ago

Cheap Flights to Grimes

Fall in love at first flight with your vacation to Grimes by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Grimes on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Grimes, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Grimes

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Grimes with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Grimes?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Grimes are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Grimes?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 12 to choose from for your flight to Grimes.

What airport is best to fly into Grimes?

When you’re planning your trip to Grimes, convenience is the name of the game. Luckily, Grimes Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Grimes must-do list.

How much are flights to Grimes?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Grimes on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $88, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Grimes?

The trick to saving a stack of cash on your flight to Grimes? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $88 right now, why wait?

Grimes Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$88

Last Minute Hotel Deals in Grimes

Red Lion Inn & Suites Grimes

Red Lion Inn & Suites Grimes

251 Gateway Cir Grimes IA
Book a stay at this business-friendly hotel in Grimes. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (615 reviews)
Good service.

Reviewed on Mar 2, 2026

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Red Lion Inn & Suites Grimes
Tru By Hilton Grimes Des Moines

Tru By Hilton Grimes Des Moines

2.5 out of 5
701 NE Gateway Drive Grimes IA
Stay at this hotel in Grimes. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Sky Zone Indoor Trampoline Park and Beaver Creek Golf Club ...
9/10 Wonderful! (38 reviews)
Everything was pretty good except for the pool being kind of small and the kids being very rowdy. I wish we would have known kind of what weekend to go there or that there was a limit on who could go to the pool when. We would have planned it on a different weekend where we had the pool, more free.If ...

Reviewed on Mar 9, 2026

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Tru By Hilton Grimes Des Moines
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,041 reviews)
The hotel amenities and staff were excellent! From 10:00 PM to 3 AM. There was nonstop street racing that was so loud I thought they were in my room. I did not sleep at all! When I mentioned it to the front desk at check out they said “yeah it happens all the time. You should’ve called the police”. ...

Reviewed on Mar 9, 2026

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Des Lux Hotel
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,012 reviews)
Breakfast not good, tv had issues

Reviewed on Mar 9, 2026

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Home2 Suites by Hilton Des Moines at Drake University
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,238 reviews)
This was great they had a gym and the room was clean. Only thing was the Lighting wasn’t very good but it was a great stay. Breakfast was great too!

Reviewed on Mar 9, 2026

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Wildwood Lodge
Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek

3 out of 5
295 South 64th st West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
The pool was nice and warm kind of small. No hot tub at this location but would be nice if they could out one in.

Reviewed on Mar 10, 2026

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Hyatt Place West Des Moines Jordan Creek
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2.5 out of 5
7625 Office Plaza Dr N West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,005 reviews)
They didn’t have a room for us so we had to find another hotel. It smelled horrible and was dirty so we were glad at least we didn’t have to stay here.

Reviewed on Mar 10, 2026

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Sonesta Simply Suites Des Moines
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
Stay at this hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,000 reviews)
Clean room

Reviewed on Mar 8, 2026

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Holiday Inn Downtown - Mercy Area by IHG
See all 839 properties in Grimes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.