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Grimes

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Grimes Flights as Low as $125

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Aug 21 - Thu, Aug 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$125 Roundtrip, found 17 hours ago
$125
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Denver Intl. to Des Moines Intl., returning Thu, Aug 21, priced at $125 found 17 hours ago
United
Fri, Aug 1 - Mon, Aug 4
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$184 Roundtrip, found 11 hours ago
$184
Roundtrip
found 11 hours ago
Select United flight, departing Fri, Aug 1 from O'Hare Intl. to Des Moines Intl., returning Mon, Aug 4, priced at $184 found 11 hours ago
United
Tue, Jul 15 - Wed, Jul 23
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$223 Roundtrip, found 15 hours ago
$223
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Jul 15 from George Bush Intercontinental to Des Moines Intl., returning Wed, Jul 23, priced at $223 found 15 hours ago
Frontier Airlines
Thu, Sep 4 - Thu, Sep 11
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$225 Roundtrip, found 6 hours ago
$225
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Thu, Sep 4 from Los Angeles Intl. to Des Moines Intl., returning Thu, Sep 11, priced at $225 found 6 hours ago
Bargain Flight
Tue, Aug 5 - Wed, Aug 13
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$233 Roundtrip, found 9 hours ago
$233
Roundtrip
found 9 hours ago
Select Bargain Flight flight, departing Tue, Aug 5 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Wed, Aug 13, priced at $233 found 9 hours ago
American Airlines
Tue, Nov 4 - Mon, Nov 10
PNS
Pensacola Intl.
DSM
Des Moines Intl.
$237 Roundtrip, found 21 hours ago
$237
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Tue, Nov 4 from Pensacola Intl. to Des Moines Intl., returning Mon, Nov 10, priced at $237 found 21 hours ago
Delta
Mon, Aug 25 - Fri, Aug 29
PHL
Philadelphia Intl.
DSM
Des Moines Intl.
$240 Roundtrip, found 6 hours ago
$240
Roundtrip
found 6 hours ago
Select Delta flight, departing Mon, Aug 25 from Philadelphia Intl. to Des Moines Intl., returning Fri, Aug 29, priced at $240 found 6 hours ago
Bargain Flight
Tue, Aug 12 - Tue, Aug 19
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$242 Roundtrip, found 5 hours ago
$242
Roundtrip
found 5 hours ago
Select Bargain Flight flight, departing Tue, Aug 12 from Sky Harbor Intl. to Des Moines Intl., returning Tue, Aug 19, priced at $242 found 5 hours ago
Bargain Flight
Tue, Jul 15 - Wed, Jul 16
ABQ
Albuquerque Intl. Sunport
DSM
Des Moines Intl.
$252 Roundtrip, found 18 hours ago
$252
Roundtrip
found 18 hours ago
Select Bargain Flight flight, departing Tue, Jul 15 from Albuquerque Intl. Sunport to Des Moines Intl., returning Wed, Jul 16, priced at $252 found 18 hours ago
Bargain Flight
Tue, Jul 22 - Tue, Jul 29
BOS
Logan Intl.
DSM
Des Moines Intl.
$258 Roundtrip, found 1 day ago
$258
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Jul 22 from Logan Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $258 found 1 day ago
Bargain Flight
Wed, Jul 9 - Wed, Jul 16
OKC
Will Rogers World
DSM
Des Moines Intl.
$263 Roundtrip, found 5 hours ago
$263
Roundtrip
found 5 hours ago
Select Bargain Flight flight, departing Wed, Jul 9 from Will Rogers World to Des Moines Intl., returning Wed, Jul 16, priced at $263 found 5 hours ago
Bargain Flight
Tue, Aug 19 - Tue, Aug 26
SEA
Seattle - Tacoma Intl.
DSM
Des Moines Intl.
$264 Roundtrip, found 18 hours ago
$264
Roundtrip
found 18 hours ago
Select Bargain Flight flight, departing Tue, Aug 19 from Seattle - Tacoma Intl. to Des Moines Intl., returning Tue, Aug 26, priced at $264 found 18 hours ago
Bargain Flight
Fri, Jul 25 - Tue, Jul 29
TPA
Tampa Intl.
DSM
Des Moines Intl.
$264 Roundtrip, found 5 hours ago
$264
Roundtrip
found 5 hours ago
Select Bargain Flight flight, departing Fri, Jul 25 from Tampa Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $264 found 5 hours ago
Delta
Tue, Jul 29 - Tue, Aug 5
JAX
Jacksonville Intl.
DSM
Des Moines Intl.
$265 Roundtrip, found 4 days ago
$265
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Jul 29 from Jacksonville Intl. to Des Moines Intl., returning Tue, Aug 5, priced at $265 found 4 days ago
Bargain Flight
Tue, Jul 15 - Thu, Jul 24
MCO
Orlando Intl.
DSM
Des Moines Intl.
$273 Roundtrip, found 4 hours ago
$273
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Tue, Jul 15 from Orlando Intl. to Des Moines Intl., returning Thu, Jul 24, priced at $273 found 4 hours ago
Bargain Flight
Wed, Jul 9 - Wed, Jul 16
SAN
San Diego Intl.
DSM
Des Moines Intl.
$288 Roundtrip, found 21 hours ago
$288
Roundtrip
found 21 hours ago
Select Bargain Flight flight, departing Wed, Jul 9 from San Diego Intl. to Des Moines Intl., returning Wed, Jul 16, priced at $288 found 21 hours ago

Cheap Flights to Grimes

Fall in love at first flight with your vacation to Grimes by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Grimes on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Grimes, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Grimes

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Grimes with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Grimes?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Grimes are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Grimes?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 7 to choose from for your flight to Grimes.

What airport is best to fly into Grimes?

When you’re planning your trip to Grimes, convenience is the name of the game. Luckily, Grimes Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Grimes must-do list.

How much are flights to Grimes?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Grimes on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $125, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Grimes?

The trick to saving a stack of cash on your flight to Grimes? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $125 right now, why wait?

Grimes Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$124

Last Minute Hotel Deals in Grimes

Red Lion Inn & Suites Grimes
Red Lion Inn & Suites Grimes
251 Gateway Cir, Grimes, IA
Book a stay at this business-friendly hotel in Grimes. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (538 reviews)
"Very clean and friendly"

Reviewed on Jun 8, 2025

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Red Lion Inn & Suites Grimes
Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton
4.5 out of 5
1000 Walnut St, Des Moines, IA
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,028 reviews)
"Nicely updated hotel in a good location. Would stay again and recommend."

Reviewed on Jun 28, 2025

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Hotel Fort Des Moines, Curio Collection by Hilton
Holiday Inn Downtown - Mercy Area by IHG
Holiday Inn Downtown - Mercy Area by IHG
3 out of 5
1050 6th Ave, Des Moines, IA
Stay at this 3-star hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (1,003 reviews)
"Nice property, clean room. Staff just weren't very friendly"

Reviewed on Jun 21, 2025

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Holiday Inn Downtown - Mercy Area by IHG
Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,511 reviews)
"This is the best place to get a good nights rest. Price is phenomenal and the whole place is very clean. I’m never disappointed when I stay here."

Reviewed on Jun 28, 2025

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Days Inn & Suites by Wyndham Des Moines Airport
Motel 6 West Des Moines, IA
Motel 6 West Des Moines, IA
2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (410 reviews)
"The rooms were refurbished on the inside which was nice, and the hotel was in a quiet area. However, there was a noisy dog in one room, people watching their tv loudly, and smokers outside, so would suggest other places if you are staying for more than a couple nights"

Reviewed on Jun 28, 2025

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Motel 6 West Des Moines, IA
Quality Inn & Suites Des Moines - Merle Hay Road
Quality Inn & Suites Des Moines - Merle Hay Road
2.5 out of 5
4995 Merle Hay Rd, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (938 reviews)
Great
"We had a few complications but they set everything right. Great people. Will definitely stay again."

Reviewed on Jun 28, 2025

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Quality Inn & Suites Des Moines - Merle Hay Road
Days Inn by Wyndham West Des Moines / Clive
Days Inn by Wyndham West Des Moines / Clive
2 out of 5
1600 NW 114th St, Clive, IA
Book a stay at this business-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jordan Creek Town Center and Clive ...
6/10 (1,001 reviews)
"The curtain isnt fully up, there is a vent cover missing from my bathroom & the flip door lock is broken off"

Reviewed on Jun 27, 2025

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Days Inn by Wyndham West Des Moines / Clive
Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,733 reviews)
"We stayed in the “Cottages” - large rooms and quiet"

Reviewed on Jun 28, 2025

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Stoney Creek Hotel Des Moines - Johnston
See all 747 properties in Grimes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.