Search Cheap Flights to
Central Iowa

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Central Iowa Flights as Low as $255

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
Sat, Mar 14 - Tue, Mar 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$255 Roundtrip, found 2 days ago
$255
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Sat, Mar 14 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $255 found 2 days ago
Frontier Airlines
Sun, Mar 15 - Tue, Mar 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$270 Roundtrip, found 4 days ago
$270
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Mar 15 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $270 found 4 days ago
Bargain Flight
Thu, Apr 2 - Mon, Apr 6
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$282 Roundtrip, found 3 days ago
$282
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Thu, Apr 2 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Mon, Apr 6, priced at $282 found 3 days ago
Frontier Airlines
Fri, Mar 13 - Tue, Mar 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$286 Roundtrip, found 4 days ago
$286
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Mar 13 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $286 found 4 days ago
American Airlines
Mon, Apr 27 - Wed, May 6
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$288 Roundtrip, found 2 days ago
$288
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Apr 27 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Wed, May 6, priced at $288 found 2 days ago
Frontier Airlines
Fri, Apr 3 - Mon, Apr 6
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Apr 3 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Mon, Apr 6, priced at $290 found 3 days ago
American Airlines
Tue, Apr 28 - Mon, May 11
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Apr 28 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Mon, May 11, priced at $290 found 3 days ago
Frontier Airlines
Mon, Mar 16 - Tue, Mar 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$291 Roundtrip, found 4 days ago
$291
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Mon, Mar 16 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $291 found 4 days ago
American Airlines
Thu, Apr 30 - Sat, May 9
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$298 Roundtrip, found 20 hours ago
$298
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Thu, Apr 30 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Sat, May 9, priced at $298 found 20 hours ago
Delta
Sat, Apr 25 - Sat, May 9
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$305 Roundtrip, found 23 hours ago
$305
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Apr 25 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Sat, May 9, priced at $305 found 23 hours ago
Frontier Airlines
Sat, Mar 14 - Tue, Mar 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$306 Roundtrip, found 2 days ago
$306
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Mar 14 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $306 found 2 days ago
United
Fri, May 1 - Sat, May 9
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$309 Roundtrip, found 2 days ago
$309
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 1 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Sat, May 9, priced at $309 found 2 days ago
Frontier Airlines
Mon, Mar 16 - Thu, Mar 19
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$310 Roundtrip, found 4 days ago
$310
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Mon, Mar 16 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Thu, Mar 19, priced at $310 found 4 days ago
American Airlines
Wed, May 27 - Tue, Jun 2
BOS
Logan Intl.
RST
Rochester Intl.
$311 Roundtrip, found 11 hours ago
$311
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, May 27 from Logan Intl. to Rochester Intl., returning Tue, Jun 2, priced at $311 found 11 hours ago
Delta
Fri, May 1 - Mon, May 11
RSW
Southwest Florida Intl.
RST
Rochester Intl.
$326 Roundtrip, found 1 day ago
$326
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, May 1 from Southwest Florida Intl. to Rochester Intl., returning Mon, May 11, priced at $326 found 1 day ago
Delta
Wed, Apr 1 - Tue, Apr 7
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$451 Roundtrip, found 3 days ago
$451
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Apr 1 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Apr 7, priced at $451 found 3 days ago

Cheap Flights to Central Iowa

Fall in love at first flight with your vacation to Central Iowa by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Central Iowa on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Central Iowa, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Central Iowa

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Central Iowa with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Central Iowa?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Central Iowa are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Central Iowa?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Central Iowa.

What airport is best to fly into Central Iowa?

When you’re planning your trip to Central Iowa, convenience is the name of the game. Luckily, Central Iowa Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Central Iowa must-do list.

How much are flights to Central Iowa?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Central Iowa on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $255, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Central Iowa?

The trick to saving a stack of cash on your flight to Central Iowa? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $255 right now, why wait?

Central Iowa Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$145

Last Minute Hotel Deals in Central Iowa

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,095 reviews)
Room was very nice! Especially the bathroom and shower. Received conflicting info on parking between the front desk and valet. Valet explained the parking ramp is $2/hr but didn’t say there is a $10 limit. Might have made a difference on where we parked.

Reviewed on Mar 12, 2026

Get rates
Hotel Fort Des Moines, Curio Collection by Hilton
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,042 reviews)
The hotel amenities and staff were excellent! From 10:00 PM to 3 AM. There was nonstop street racing that was so loud I thought they were in my room. I did not sleep at all! When I mentioned it to the front desk at check out they said “yeah it happens all the time. You should’ve called the police”. ...

Reviewed on Mar 9, 2026

Get rates
Des Lux Hotel
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,001 reviews)
Friendly front desk staff. Room was clean and nice. Easy parking.

Reviewed on Mar 12, 2026

Get rates
Home2 Suites by Hilton Des Moines at Drake University
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,238 reviews)
This was great they had a gym and the room was clean. Only thing was the Lighting wasn’t very good but it was a great stay. Breakfast was great too!

Reviewed on Mar 9, 2026

Get rates
Wildwood Lodge
Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek

3 out of 5
295 South 64th st West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
Good

Reviewed on Mar 11, 2026

Get rates
Hyatt Place West Des Moines Jordan Creek
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2.5 out of 5
7625 Office Plaza Dr N West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,007 reviews)
They didn’t have a room for us so we had to find another hotel. It smelled horrible and was dirty so we were glad at least we didn’t have to stay here.

Reviewed on Mar 10, 2026

Get rates
Sonesta Simply Suites Des Moines
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
Stay at this hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,001 reviews)
Clean room, bar was stocked well, air conditioning wouldn't work quite right it was hot in our room.

Reviewed on Mar 12, 2026

Get rates
Holiday Inn Downtown - Mercy Area by IHG
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,751 reviews)
Just needed for a room near the airport for an early morning departure. This fit the bill. It was inexpensive and clean. Complimentary continental breakfast service starts really early (4:30 a.m. I think!) but we did not partake. I would stay again.

Reviewed on Mar 12, 2026

Get rates
Days Inn & Suites by Wyndham Des Moines Airport
See all 1,608 properties in Central Iowa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,751 reviews)
Just needed for a room near the airport for an early morning departure. This fit the bill. It was inexpensive and clean. Complimentary continental breakfast service starts really early (4:30 a.m. I think!) but we did not partake. I would stay again.

Reviewed on Mar 12, 2026

Get rates
Days Inn & Suites by Wyndham Des Moines Airport
Hilton Garden Inn Des Moines Airport

Hilton Garden Inn Des Moines Airport

3 out of 5
6800 Fleur Drive Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Casey's Center and A. ...
9/10 Wonderful! (693 reviews)
NA

Reviewed on Mar 5, 2026

Get rates
Hilton Garden Inn Des Moines Airport
AC Hotel Des Moines East Village

AC Hotel Des Moines East Village

3 out of 5
401 East Grand Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
9.2/10 Wonderful! (409 reviews)
Super nice hotel. Right downtown! Great rooftop bar! We went to a concert at Woolley’s and it was right around the corner. Will definitely stay here again!

Reviewed on Mar 1, 2026

Get rates
AC Hotel Des Moines East Village
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 out of 5
1920 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,008 reviews)
Yes

Reviewed on Mar 10, 2026

Get rates
AmericInn by Wyndham Des Moines Airport
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,175 reviews)
Perfect stay. From staff to cleanliness it was perfect.

Reviewed on Mar 11, 2026

Get rates
Baymont by Wyndham Des Moines Airport
Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center

2.5 out of 5
929 3rd St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,005 reviews)
Clean room

Reviewed on Mar 9, 2026

Get rates
Comfort Inn & Suites Event Center
See all 1,608 properties in Central Iowa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.