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Cambridge

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Cambridge Flights as Low as $160

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, May 21 - Fri, May 30
DEN
Denver Intl.
DSM
Des Moines Intl.
$160 Roundtrip, found 4 days ago
$160
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, May 21 from Denver Intl. to Des Moines Intl., returning Fri, May 30, priced at $160 found 4 days ago
American Airlines
Tue, Jun 24 - Tue, Jul 22
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$203 Roundtrip, found 5 hours ago
$203
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Jun 24 from Sky Harbor Intl. to Des Moines Intl., returning Tue, Jul 22, priced at $203 found 5 hours ago
United
Wed, Jun 4 - Wed, Jun 11
DEN
Denver Intl.
DSM
Des Moines Intl.
$207 Roundtrip, found 5 days ago
$207
Roundtrip
found 5 days ago
Select United flight, departing Wed, Jun 4 from Denver Intl. to Des Moines Intl., returning Wed, Jun 11, priced at $207 found 5 days ago
Delta
Sat, May 24 - Wed, May 28
DEN
Denver Intl.
DSM
Des Moines Intl.
$210 Roundtrip, found 4 days ago
$210
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, May 24 from Denver Intl. to Des Moines Intl., returning Wed, May 28, priced at $210 found 4 days ago
Frontier Airlines
Mon, May 12 - Wed, May 21
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$241 Roundtrip, found 1 day ago
$241
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, May 12 from Los Angeles Intl. to Des Moines Intl., returning Wed, May 21, priced at $241 found 1 day ago
Frontier Airlines
Tue, May 6 - Fri, May 9
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$242 Roundtrip, found 11 hours ago
$242
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Tue, May 6 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Fri, May 9, priced at $242 found 11 hours ago
Frontier Airlines
Fri, May 2 - Wed, May 7
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$247 Roundtrip, found 11 hours ago
$247
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Fri, May 2 from George Bush Intercontinental to Des Moines Intl., returning Wed, May 7, priced at $247 found 11 hours ago
Bargain Flight
Wed, Jul 9 - Wed, Jul 16
SAN
San Diego Intl.
DSM
Des Moines Intl.
$254 Roundtrip, found 5 days ago
$254
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Wed, Jul 9 from San Diego Intl. to Des Moines Intl., returning Wed, Jul 16, priced at $254 found 5 days ago
Delta
Sat, May 31 - Tue, Jun 10
ABE
Lehigh Valley Intl.
DSM
Des Moines Intl.
$263 Roundtrip, found 3 days ago
$263
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, May 31 from Lehigh Valley Intl. to Des Moines Intl., returning Tue, Jun 10, priced at $263 found 3 days ago
Delta
Wed, Jul 23 - Tue, Jul 29
TPA
Tampa Intl.
DSM
Des Moines Intl.
$285 Roundtrip, found 2 days ago
$285
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jul 23 from Tampa Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $285 found 2 days ago
American Airlines
Fri, Sep 5 - Sun, Sep 7
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$287 Roundtrip, found 17 hours ago
$287
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Fri, Sep 5 from McClellan-Palomar to Des Moines Intl., returning Sun, Sep 7, priced at $287 found 17 hours ago
Delta
Wed, May 7 - Wed, May 14
DAY
James M. Cox Dayton Intl.
DSM
Des Moines Intl.
$288 Roundtrip, found 12 hours ago
$288
Roundtrip
found 12 hours ago
Select Delta flight, departing Wed, May 7 from James M. Cox Dayton Intl. to Des Moines Intl., returning Wed, May 14, priced at $288 found 12 hours ago
Bargain Flight
Fri, Jun 27 - Tue, Jul 1
PDX
Portland Intl.
DSM
Des Moines Intl.
$290 Roundtrip, found 19 hours ago
$290
Roundtrip
found 19 hours ago
Select Bargain Flight flight, departing Fri, Jun 27 from Portland Intl. to Des Moines Intl., returning Tue, Jul 1, priced at $290 found 19 hours ago
Delta
Wed, May 14 - Wed, May 21
ILM
Wilmington Intl.
DSM
Des Moines Intl.
$292 Roundtrip, found 15 hours ago
$292
Roundtrip
found 15 hours ago
Select Delta flight, departing Wed, May 14 from Wilmington Intl. to Des Moines Intl., returning Wed, May 21, priced at $292 found 15 hours ago
American Airlines
Tue, May 20 - Thu, May 29
JFK
John F. Kennedy Intl.
DSM
Des Moines Intl.
$357 Roundtrip, found 13 hours ago
$357
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, May 20 from John F. Kennedy Intl. to Des Moines Intl., returning Thu, May 29, priced at $357 found 13 hours ago
United
Mon, May 5 - Wed, May 7
OMA
Eppley Field
DSM
Des Moines Intl.
$811 Roundtrip, found 1 day ago
$811
Roundtrip
found 1 day ago
Select United flight, departing Mon, May 5 from Eppley Field to Des Moines Intl., returning Wed, May 7, priced at $811 found 1 day ago

Cheap Flights to Cambridge

Fall in love at first flight with your vacation to Cambridge by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cambridge on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cambridge, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cambridge

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cambridge with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Cambridge?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cambridge are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cambridge?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Cambridge.

What airport is best to fly into Cambridge?

When you’re planning your trip to Cambridge, convenience is the name of the game. Luckily, Cambridge Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Cambridge must-do list.

How much are flights to Cambridge?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cambridge on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $160, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cambridge?

The trick to saving a stack of cash on your flight to Cambridge? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $160 right now, why wait?

Cambridge Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$160

Last Minute Hotel Deals in Cambridge

Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
The price is $122 per night from May 4 to May 5
$122
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,666 reviews)
"!"

Reviewed on Apr 29, 2025

Stoney Creek Hotel Des Moines - Johnston
Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton
4.5 out of 5
1000 Walnut St, Des Moines, IA
The price is $153 per night from May 26 to May 27
$153
includes taxes & fees
May 26 - May 27
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (979 reviews)
"The hotel was old, charming and in excellent condition. The staff was very friendly and attentive. The bed was comfortable and quiet. There were many restaurants with in walking distance. We are coming over to Hilton Honors from being IHG members for sometime, the IHG hotels are becoming expensive ..."

Reviewed on Apr 28, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Surety Hotel
Surety Hotel
4 out of 5
206 6th Ave., Des Moines, IA
The price is $194 per night from May 18 to May 19
$194
includes taxes & fees
May 18 - May 19
Stay at this 4-star hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the bar in our reviews. ...
9.2/10 Wonderful! (998 reviews)
"Everything was perfect! Great hotel!!"

Reviewed on Apr 28, 2025

Surety Hotel
Des Lux Hotel
Des Lux Hotel
3.5 out of 5
800 Locust St, Des Moines, IA
The price is $223 per night from May 4 to May 5
$223
includes taxes & fees
May 4 - May 5
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,000 reviews)
"Beautiful hotel!"

Reviewed on Apr 27, 2025

Des Lux Hotel
Sonesta Essential Des Moines
Sonesta Essential Des Moines
2 out of 5
4755 Merle Hay Road, Des Moines, IA
The price is $88 per night from May 12 to May 13
$88
includes taxes & fees
May 12 - May 13
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,001 reviews)
"Thank you"

Reviewed on Apr 27, 2025

Sonesta Essential Des Moines
Wildwood Lodge
Wildwood Lodge
3 out of 5
11431 Forest Ave, Clive, IA
The price is $122 per night from May 4 to May 5
$122
includes taxes & fees
May 4 - May 5
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,236 reviews)
"This was a cute little hotel with a great staff! The breakfast option was great to get before hitting the road!"

Reviewed on Apr 28, 2025

Wildwood Lodge
Home2 Suites by Hilton Des Moines at Drake University
Home2 Suites by Hilton Des Moines at Drake University
3 out of 5
2650 University Ave., Des Moines, IA
The price is $113 per night from May 11 to May 12
$113
includes taxes & fees
May 11 - May 12
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (815 reviews)
"Friendly staff, clean and an excellent location."

Reviewed on Apr 30, 2025

Home2 Suites by Hilton Des Moines at Drake University
La Quinta by Wyndham Altoona Des Moines
La Quinta by Wyndham Altoona Des Moines
2.5 out of 5
1785 11th Street NW, Altoona, IA
The price is $106 per night from May 4 to May 5
$106
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Altoona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,582 reviews)
"Room was clean and loved walk-in shower. Didn't have enough carts for clothes and luggage."

Reviewed on Apr 26, 2025

La Quinta by Wyndham Altoona Des Moines
See all 662 properties in Cambridge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.