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Cambridge

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Cambridge Flights as Low as $142

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, Jun 1 - Wed, Jun 10
DEN
Denver Intl.
DSM
Des Moines Intl.
$142 Roundtrip, found 5 hours ago
$142
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Mon, Jun 1 from Denver Intl. to Des Moines Intl., returning Wed, Jun 10, priced at $142 found 5 hours ago
Frontier Airlines
Tue, May 26 - Wed, Jun 10
ELP
El Paso Intl.
DSM
Des Moines Intl.
$215 Roundtrip, found 22 hours ago
$215
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Tue, May 26 from El Paso Intl. to Des Moines Intl., returning Wed, Jun 10, priced at $215 found 22 hours ago
Frontier Airlines
Thu, Aug 13 - Mon, Aug 17
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$218 Roundtrip, found 1 day ago
$218
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Aug 13 from Sky Harbor Intl. to Des Moines Intl., returning Mon, Aug 17, priced at $218 found 1 day ago
Frontier Airlines
Mon, Jul 27 - Wed, Aug 5
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$230 Roundtrip, found 5 hours ago
$230
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Mon, Jul 27 from Los Angeles Intl. to Des Moines Intl., returning Wed, Aug 5, priced at $230 found 5 hours ago
Frontier Airlines
Thu, Jul 23 - Wed, Aug 5
BOI
Boise
DSM
Des Moines Intl.
$240 Roundtrip, found 5 hours ago
$240
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Thu, Jul 23 from Boise to Des Moines Intl., returning Wed, Aug 5, priced at $240 found 5 hours ago
American Airlines
Tue, Jun 2 - Mon, Jun 15
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$244 Roundtrip, found 9 hours ago
$244
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Jun 2 from O'Hare Intl. to Des Moines Intl., returning Mon, Jun 15, priced at $244 found 9 hours ago
Frontier Airlines
Wed, Jun 3 - Fri, Jun 5
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$246 Roundtrip, found 4 days ago
$246
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Jun 3 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Fri, Jun 5, priced at $246 found 4 days ago
Frontier Airlines
Thu, May 28 - Wed, Jun 3
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$246 Roundtrip, found 6 days ago
$246
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, May 28 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Wed, Jun 3, priced at $246 found 6 days ago
Bargain Flight
Tue, Jun 23 - Tue, Jun 30
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$276 Roundtrip, just found
$276
Roundtrip
just found
Select Bargain Flight flight, departing Tue, Jun 23 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Tue, Jun 30, priced at $276 just found
Delta
Tue, Jun 16 - Tue, Jun 23
RDU
Raleigh - Durham Intl.
DSM
Des Moines Intl.
$298 Roundtrip, found 1 day ago
$298
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 16 from Raleigh - Durham Intl. to Des Moines Intl., returning Tue, Jun 23, priced at $298 found 1 day ago
Bargain Flight
Thu, Jul 16 - Sun, Jul 19
CVG
Cincinnati - Northern Kentucky Intl.
DSM
Des Moines Intl.
$301 Roundtrip, found 1 day ago
$301
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Jul 16 from Cincinnati - Northern Kentucky Intl. to Des Moines Intl., returning Sun, Jul 19, priced at $301 found 1 day ago
Delta
Tue, Sep 1 - Sat, Sep 12
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$339 Roundtrip, found 6 days ago
$339
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Sep 1 from Newark Liberty Intl. Airport to Des Moines Intl., returning Sat, Sep 12, priced at $339 found 6 days ago
Delta
Wed, Aug 12 - Mon, Aug 31
MSO
Missoula Intl.
DSM
Des Moines Intl.
$339 Roundtrip, found 19 hours ago
$339
Roundtrip
found 19 hours ago
Select Delta flight, departing Wed, Aug 12 from Missoula Intl. to Des Moines Intl., returning Mon, Aug 31, priced at $339 found 19 hours ago
United
Mon, Jun 1 - Wed, Jun 3
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$345 Roundtrip, found 1 day ago
$345
Roundtrip
found 1 day ago
Select United flight, departing Mon, Jun 1 from McClellan-Palomar to Des Moines Intl., returning Wed, Jun 3, priced at $345 found 1 day ago
Delta
Tue, Jun 9 - Wed, Jun 17
BHM
Birmingham Intl.
DSM
Des Moines Intl.
$356 Roundtrip, found 1 day ago
$356
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 9 from Birmingham Intl. to Des Moines Intl., returning Wed, Jun 17, priced at $356 found 1 day ago
Delta
Sat, Aug 8 - Sat, Aug 15
LGA
LaGuardia
DSM
Des Moines Intl.
$365 Roundtrip, found 20 hours ago
$365
Roundtrip
found 20 hours ago
Select Delta flight, departing Sat, Aug 8 from LaGuardia to Des Moines Intl., returning Sat, Aug 15, priced at $365 found 20 hours ago

Cheap Flights to Cambridge

Fall in love at first flight with your vacation to Cambridge by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cambridge on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cambridge, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cambridge

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cambridge with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Cambridge?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cambridge are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cambridge?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Cambridge.

What airport is best to fly into Cambridge?

When you’re planning your trip to Cambridge, convenience is the name of the game. Luckily, Cambridge Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Cambridge must-do list.

How much are flights to Cambridge?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cambridge on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $142, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cambridge?

The trick to saving a stack of cash on your flight to Cambridge? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $142 right now, why wait?

Cambridge Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$141

Last Minute Hotel Deals in Cambridge

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,144 reviews)
Who rated this hotel 9.8? No bellman all during stay. Room had no radio/clock, no pen or notepad, no room service menu or breakfast door hanger. It did have toilet tissue equal to a good Motel 6 and nicely black colored grout in shower. Free Wi-Fi only if you signed up for Hilton app. Breakfast not ...

Reviewed on May 11, 2026

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Hotel Fort Des Moines, Curio Collection by Hilton
Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

3 out of 5
2100 Green Hills Drive Ames IA
Book a stay at this business-friendly hotel in Ames. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,300 reviews)
Hotel provided all necessary services

Reviewed on May 11, 2026

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Gateway Hotel and Conference Center at Iowa State University
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,064 reviews)
Everything was great, cleanliness, beautiful property. The breakfast was out of quite a few options and the coffee wasn’t working. But everything else was great!

Reviewed on May 11, 2026

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Des Lux Hotel
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,258 reviews)
Breakfast was fresh and good. Wonderful firepit and so relaxing! Hottub was broke down. But had a very good time.

Reviewed on May 11, 2026

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Wildwood Lodge
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,852 reviews)
Yes to both

Reviewed on May 10, 2026

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Stoney Creek Hotel Des Moines - Johnston
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,017 reviews)
The young man working the overnight front desk should be running his own hotel one day! I’m rarely impressed with professional acumen, kindness, and sincere effort to go above and beyond. I literally watched this young man treat a dozen or more people checking in with such professionalism that I ...

Reviewed on May 12, 2026

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Home2 Suites by Hilton Des Moines at Drake University
Sonesta Essential Des Moines

Sonesta Essential Des Moines

2 out of 5
4755 Merle Hay Road Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.4/10 Good! (1,009 reviews)
This hotel was not cleaned and falling apart. Our room was disgusting and the hotel was not safe. There were homeless people in the lobby and using the bathrooms inside the hotel. We ended up getting a refund and going to a different hotel.

Reviewed on May 11, 2026

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Sonesta Essential Des Moines
Sheraton West Des Moines Hotel

Sheraton West Des Moines Hotel

3.5 out of 5
1800 50th St West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful ...
8.2/10 Very Good! (1,006 reviews)
I checked in on Friday with my service dog. The staff was great. I was asked what floor and I suggested one closest to the ground. The hotel was very clean and stocked. My bed was very comfortable and I definitely will be back and I highly recommend

Reviewed on May 10, 2026

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Sheraton West Des Moines Hotel
See all 762 properties in Cambridge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.