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Hotels in Hartsville

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Last Minute Hot Rate® Hotel Deals in Hartsville

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Choose from 150 Hartsville Hotel Deals

Days Inn by Wyndham Florence/I-95 North
Days Inn by Wyndham Florence/I-95 North
2 out of 5
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
  • 50 min drive from Neptune Island Waterpark
The price is $54 per night from May 22 to May 23
$54
per night
May 22 - May 23
Stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,000 reviews)
"The lady at the front desk on arrival, and a different one upon checkout , both were great"

Reviewed on May 5, 2024

Days Inn by Wyndham Florence/I-95 North
Fairfield Inn by Marriott Hartsville
Fairfield Inn by Marriott Hartsville
2.5 out of 5
200 S 4th St, Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
The price is $107 per night from May 19 to May 20
$107
per night
May 19 - May 20
Stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (548 reviews)
"Front desk was fantastic in helping us add a night to our stay!"

Reviewed on May 4, 2024

Fairfield Inn by Marriott Hartsville
Quality Inn
Quality Inn
2.5 out of 5
903 S 5th Street, Hartsville, SC
  • 4 min drive from Neptune Island Waterpark
The price is $61 per night from May 26 to May 27
$61
per night
May 26 - May 27
Stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Neptune Island ...
6/10 (224 reviews)
"Good"

Reviewed on May 4, 2024

Quality Inn
Hampton Inn & Suites Hartsville
Hampton Inn & Suites Hartsville
2.5 out of 5
203 East Carolina Ave., Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
The price is $144 per night from May 16 to May 17
$144
per night
May 16 - May 17
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Neptune Island Waterpark are located ...
9.2/10 Wonderful! (390 reviews)
"The property was central to where our meeting was being held. Parking was plentiful. Clean."

Reviewed on Apr 21, 2024

Hampton Inn & Suites Hartsville
The Landmark Inn
The Landmark Inn
2.5 out of 5
1301 South 4th Street, Hartsville, SC
  • 6 min drive from Neptune Island Waterpark
The price is $80 per night from May 9 to May 10
$80
per night
May 9 - May 10
Stay at this business-friendly motel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Neptune Island ...
7/10 Good! (242 reviews)
Turkey Hunting Trip
"This hotel isn't a great stay, but it served its purpose for a couple guys on a hunting trip. I would stay again for a similar purpose."

Reviewed on Apr 6, 2024

The Landmark Inn
The Mantissa Hotel
The Mantissa Hotel
3 out of 5
130 East Carolina Ave, Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
The price is $180 per night from May 20 to May 21
$180
per night
May 20 - May 21
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Neptune Island Waterpark ...
9/10 Wonderful! (191 reviews)
"Really nice , convenient, and comfortable..."

Reviewed on May 3, 2024

The Mantissa Hotel
Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
  • 51 min drive from Neptune Island Waterpark
The price is $67 per night from May 28 to May 29
$67
per night
May 28 - May 29
Stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.8/10 Excellent! (1,889 reviews)
"I'm old enough to remember what a real motel (motorhotel) was, where you literally drive your car up to your door. Not much in the way of amenities, and you are not part of an enclosed hotel structure. Nevertheless, the room was fine - clean, everything worked and bathroom facilities obviously recently ..."

Reviewed on May 5, 2024

Howard Johnson by Wyndham Florence
Quality Inn And Suites Civic
Quality Inn And Suites Civic
2.5 out of 5
150 Dunbarton Dr, Florence, SC
  • 48 min drive from Neptune Island Waterpark
The price is $90 per night from May 14 to May 15
$90
per night
May 14 - May 15
Stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
7.8/10 Good! (1,008 reviews)
"The room was clean and the property is pleasant, but I'm not sure the bed linens had been changed. The beds had been made and all the bath linens were new though. The front desk staff were very nice and helpful."

Reviewed on May 5, 2024

Quality Inn And Suites Civic
Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
  • 51 min drive from Neptune Island Waterpark
The price is $79 per night from May 27 to May 28
$79
per night
May 27 - May 28
Stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,563 reviews)
"I had an "accessable" room but it had a bath tub instead of a walk-in shower. I always request accessable rooms because it's difficult to step into a bath tub."

Reviewed on May 6, 2024

Park Inn by Radisson Florence, SC
La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence
2.5 out of 5
2123 W Lucas St, Florence, SC
  • 50 min drive from Neptune Island Waterpark
The price is $89 per night from Jun 2 to Jun 3
$89
per night
Jun 2 - Jun 3
Stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8/10 Very Good! (1,518 reviews)
"Clean rooms"

Reviewed on May 5, 2024

La Quinta Inn & Suites by Wyndham Florence
Comfort Inn & Suites
Comfort Inn & Suites
2.5 out of 5
527 Woody Jones Blvd, Florence, SC
  • 49 min drive from Neptune Island Waterpark
The price is $110 per night from Jun 3 to Jun 4
$110
per night
Jun 3 - Jun 4
Stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,006 reviews)
"We could have walked to the site of our event and food, etc. was also very close but the hotel was quiet, away from traffic."

Reviewed on May 5, 2024

Comfort Inn & Suites
Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3 out of 5
100 East Evans Street Florence, Florence, SC
  • 58 min drive from Neptune Island Waterpark
The price is $96 per night from May 19 to May 20
$96
per night
May 19 - May 20
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (811 reviews)
"Beautiful hotel, convenient to where my family met us"

Reviewed on May 6, 2024

Hyatt Place Florence Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Hartsville

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Hartsville hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Hartsville.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Hartsville’s 150 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $54. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Hartsville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Hartsville. No matter your reason for visiting Hartsville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Hartsville hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Hartsville for as low as $54.

How many hotels are there in Hartsville?

With over 150 hotels in Hartsville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $54.

How to find cheap car rentals in Hartsville?

Finding a cheap car rental deal in Hartsville is as easy as scoring cheap hotels in Hartsville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Hartsville now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Hartsville right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.