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Main Street Vacation Packages

3-4 Night Vacations in Main Street

Price found within the past 48 hours. Click for updated prices.
Sonesta Simply Suites Detroit Novi
Graduate Ann Arbor
Sonesta Select Detroit Novi
Hyatt Place Detroit/Livonia

Cheap Hotel Deals in Main Street

Wyndham Garden Ann Arbor

Wyndham Garden Ann Arbor

3 out of 5
2900 Jackson Ave, Ann Arbor, MI
Stay at this 3-star business-friendly hotel in Ann Arbor. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Wyndham Garden Ann Arbor
Weber's Hotel & Restaurant

Weber's Hotel & Restaurant

4 out of 5
3050 Jackson Road, Ann Arbor, MI
Book a stay at this boutique hotel in Ann Arbor. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the pool and the restaurant in our reviews. ...
Weber's Hotel & Restaurant
Graduate Ann Arbor

Graduate Ann Arbor

4 out of 5
615 E Huron Street, Ann Arbor, MI
Book a stay at this business-friendly hotel in Ann Arbor. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Graduate Ann Arbor
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Ann Arbor Regent Hotel & Suites

Ann Arbor Regent Hotel & Suites

3 out of 5
2455 Carpenter Road, Ann Arbor, MI
Book a stay at this business-friendly hotel in Ann Arbor. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Ann Arbor Regent Hotel & Suites
The Kensington Hotel

The Kensington Hotel

3.5 out of 5
3500 South State Street, Ann Arbor, MI
Book a stay at this business-friendly hotel in Ann Arbor. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
The Kensington Hotel
Saint John's Resort

Saint John's Resort

4 out of 5
44045 Five Mile Road, Plymouth, MI
Stay at this 4-star boutique hotel in Plymouth. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in our reviews. ...
Saint John's Resort
The University Inn Ann Arbor

The University Inn Ann Arbor

2 out of 5
2424 E Stadium Blvd, Ann Arbor, MI
Stay at this hotel in Ann Arbor. Enjoy free WiFi, free parking, and a picnic area. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
The University Inn Ann Arbor
Hyatt Place Ann Arbor

Hyatt Place Ann Arbor

3.5 out of 5
3223 S. State Street, Ann Arbor, MI
Stay at this 3.5-star business-friendly hotel in Ann Arbor. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the bar in ...
Hyatt Place Ann Arbor
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Find cheap hotels in Main Street

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Main Street hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Main Street.

Choosing the right hotel in Michigan has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Main Street’s 566 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $79. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Main Street hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Main Street. No matter your reason for visiting Main Street, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Main Street hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Main Street for as low as $79.

How many hotels are there in Main Street?

With over 566 hotels in Main Street, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $79.

How to find cheap car rentals in Main Street?

Finding a cheap car rental deal in Ann Arbor is as easy as scoring cheap hotels in Main Street. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Main Street now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Main Street right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.