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4 Star Hotels in Mission Valley

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Featured 4 Star Mission Valley Hotels

Sheraton San Diego Hotel and Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from Hotel Circle
The price is $176 per night from May 30 to May 31
$176
per night
May 30 - May 31
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 6 restaurants, and a marina. Our guests praise the helpful staff and the clean ...
Sheraton San Diego Hotel and Marina
Manchester Grand Hyatt San Diego
4 out of 5
Fully refundable
  • 8 min drive from Hotel Circle
The price is $199 per night from May 27 to May 28
$199
per night
May 27 - May 28
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from Hotel Circle
The price is $161 per night from May 27 to May 28
$161
per night
May 27 - May 28
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the ...
Wyndham San Diego Bayside
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Hyatt Regency Mission Bay Spa and Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 21 min walk from Hotel Circle
The price is $189 per night from May 27 to May 28
$189
per night
May 27 - May 28
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
Hyatt Regency Mission Bay Spa and Marina
Marriott Marquis San Diego Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Hotel Circle
The price is $229 per night from May 31 to Jun 1
$229
per night
May 31 - Jun 1
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in ...
Marriott Marquis San Diego Marina
Hard Rock Hotel San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Hotel Circle
The price is $209 per night from May 27 to May 28
$209
per night
May 27 - May 28
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the restaurant and the helpful staff in our reviews. ...
Hard Rock Hotel San Diego
Loews Coronado Bay Resort
4 out of 5
Fully refundableReserve now, pay when you stay
  • 22 min drive from Hotel Circle
The price is $219 per night from May 27 to May 28
$219
per night
May 27 - May 28
Stay at this 4-star beach hotel in Coronado. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Loews Coronado Bay Resort
Legacy Resort Hotel & Spa
4 out of 5
Fully refundableReserve now, pay when you stay
  • 2 min walk from Hotel Circle
The price is $199 per night from May 27 to May 28
$199
per night
May 27 - May 28
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the pool in our ...
Legacy Resort Hotel & Spa
Hilton San Diego Bayfront
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Hotel Circle
The price is $175 per night from May 26 to May 27
$175
per night
May 26 - May 27
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hilton San Diego Bayfront
San Diego Marriott Gaslamp Quarter
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Hotel Circle
The price is $169 per night from May 27 to May 28
$169
per night
May 27 - May 28
Book a stay at this business-friendly hotel in San Diego. Enjoy 2 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the bar and the helpful ...
San Diego Marriott Gaslamp Quarter
Embassy Suites by Hilton San Diego Bay Downtown
4 out of 5
  • 8 min drive from Hotel Circle
The price is $215 per night from May 27 to May 28
$215
per night
May 27 - May 28
Book a stay at this family-friendly hotel in San Diego. Enjoy room service, a fitness center, and WiFi (surcharge). Our guests praise the helpful staff and the ...
Embassy Suites by Hilton San Diego Bay Downtown
Paradise Point Resort & Spa
4 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min walk from Hotel Circle
The price is $209 per night from May 27 to May 28
$209
per night
May 27 - May 28
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-Star Hotels in Mission Valley

If you're ready to live the good life, but not break the bank, it's time to look into a 4-star hotel in Mission Valley for your next vacation. You'll get all the perks you've been dreaming of (and then some) at a rate within your means. Sprawl out on high thread-count sheets, work on your tan by the scenic pool, indulge at a world-class restaurant, take a break from it all at the in-house spa ... All this and more is at your beck and call at Mission Valley 4-star hotels.

The 4 stars are aligned

So what's the star rating all about? Here's how it works: A hotel's star rating doesn't have much to do with the price of your room, and more to do with the glowing amenities. 4-star hotels in Mission Valley, San Diego, and everywhere else, often have all those fancy extras that make you go "Oh," "Wow," and "YES!" Think amenities like opulent bedding, sophisticated electronics, personalized concierge service, and cafes that make dining in a meal for the books.

Written in the stars

You know there are as many cool spots, divey lounges, and memory-making music venues as there are stars in the sky. But you'll need the funds to check them all off. That's why we give you the chance to save up to 60% with the Hotwire Hot Rate. You can book Mission Valley 4-star hotels and still have enough spending money to paint the town red. We have so many awesome options for your stay that we thought we'd to make it a bit easier to find the right hotel. Filter the best 4-star hotels in Mission Valley by:

  • Hotwire Hot Rate: With so many amazing hotels to choose from, we'll grab you a sweet deal on a room by telling you your hotel name after you book. Wishing on 4 stars? Not necessary.
  • Price: With prices as low as $161, we know you'll find a cheap 4-star hotel in Mission Valley that won't break the bank.
  • Amenities: What makes up your vacation wish list? Heated pool? Full-service spa? 24-hour room service? Find a hotel that'll send you over the moon.

You deserve the finer things. Perks galore and the sweetest spot to recharge in Mission Valley without blowing all of your fun money. When you book a Hotwire Hot Rate, you score that stellar Mission Valley 4-star hotel and have cash left to do everything you want on your superstar vacay. Hotwire has 8,272 Mission Valley hotels waiting for you, but the most popular rooms aren't available long so book your room today.