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Salem

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Salem Flights as Low as $291

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Wed, Sep 30 - Tue, Oct 13
FLL
Fort Lauderdale - Hollywood Intl.
ROA
Roanoke Regional
$291 Roundtrip, found 9 hours ago
$291
Roundtrip
found 9 hours ago
Select Delta flight, departing Wed, Sep 30 from Fort Lauderdale - Hollywood Intl. to Roanoke Regional, returning Tue, Oct 13, priced at $291 found 9 hours ago
Bargain Flight
Wed, Oct 21 - Sat, Oct 24
SAN
San Diego Intl.
ROA
Roanoke Regional
$295 Roundtrip, found 21 hours ago
$295
Roundtrip
found 21 hours ago
Select Bargain Flight flight, departing Wed, Oct 21 from San Diego Intl. to Roanoke Regional, returning Sat, Oct 24, priced at $295 found 21 hours ago
Bargain Flight
Sat, Oct 24 - Wed, Oct 28
PSP
Palm Springs Intl.
ROA
Roanoke Regional
$297 Roundtrip, found 21 hours ago
$297
Roundtrip
found 21 hours ago
Select Bargain Flight flight, departing Sat, Oct 24 from Palm Springs Intl. to Roanoke Regional, returning Wed, Oct 28, priced at $297 found 21 hours ago
United
Wed, Aug 12 - Mon, Aug 31
ORD
O'Hare Intl.
ROA
Roanoke Regional
$299 Roundtrip, found 6 days ago
$299
Roundtrip
found 6 days ago
Select United flight, departing Wed, Aug 12 from O'Hare Intl. to Roanoke Regional, returning Mon, Aug 31, priced at $299 found 6 days ago
American Airlines
Wed, Aug 12 - Mon, Aug 31
ORD
O'Hare Intl.
ROA
Roanoke Regional
$299 Roundtrip, found 6 days ago
$299
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Aug 12 from O'Hare Intl. to Roanoke Regional, returning Mon, Aug 31, priced at $299 found 6 days ago
United
Mon, Sep 28 - Tue, Oct 6
EWR
Newark Liberty Intl. Airport
ROA
Roanoke Regional
$303 Roundtrip, found 21 hours ago
$303
Roundtrip
found 21 hours ago
Select United flight, departing Mon, Sep 28 from Newark Liberty Intl. Airport to Roanoke Regional, returning Tue, Oct 6, priced at $303 found 21 hours ago
United
Fri, Aug 28 - Wed, Sep 2
FLL
Fort Lauderdale - Hollywood Intl.
ROA
Roanoke Regional
$305 Roundtrip, found 9 hours ago
$305
Roundtrip
found 9 hours ago
Select United flight, departing Fri, Aug 28 from Fort Lauderdale - Hollywood Intl. to Roanoke Regional, returning Wed, Sep 2, priced at $305 found 9 hours ago
American Airlines
Wed, Aug 12 - Mon, Aug 31
ORD
O'Hare Intl.
ROA
Roanoke Regional
$309 Roundtrip, found 6 days ago
$309
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Aug 12 from O'Hare Intl. to Roanoke Regional, returning Mon, Aug 31, priced at $309 found 6 days ago
Delta
Mon, Sep 28 - Tue, Oct 6
EWR
Newark Liberty Intl. Airport
ROA
Roanoke Regional
$318 Roundtrip, found 21 hours ago
$318
Roundtrip
found 21 hours ago
Select Delta flight, departing Mon, Sep 28 from Newark Liberty Intl. Airport to Roanoke Regional, returning Tue, Oct 6, priced at $318 found 21 hours ago
United
Wed, Aug 12 - Mon, Aug 31
ORD
O'Hare Intl.
ROA
Roanoke Regional
$319 Roundtrip, found 6 days ago
$319
Roundtrip
found 6 days ago
Select United flight, departing Wed, Aug 12 from O'Hare Intl. to Roanoke Regional, returning Mon, Aug 31, priced at $319 found 6 days ago
Delta
Wed, Sep 30 - Sun, Oct 18
FLL
Fort Lauderdale - Hollywood Intl.
ROA
Roanoke Regional
$322 Roundtrip, found 9 hours ago
$322
Roundtrip
found 9 hours ago
Select Delta flight, departing Wed, Sep 30 from Fort Lauderdale - Hollywood Intl. to Roanoke Regional, returning Sun, Oct 18, priced at $322 found 9 hours ago
United
Wed, Aug 12 - Mon, Aug 31
ORD
O'Hare Intl.
ROA
Roanoke Regional
$322 Roundtrip, found 6 days ago
$322
Roundtrip
found 6 days ago
Select United flight, departing Wed, Aug 12 from O'Hare Intl. to Roanoke Regional, returning Mon, Aug 31, priced at $322 found 6 days ago
Delta
Sat, Oct 24 - Sun, Oct 25
ONT
Ontario Intl. Airport
ROA
Roanoke Regional
$379 Roundtrip, found 21 hours ago
$379
Roundtrip
found 21 hours ago
Select Delta flight, departing Sat, Oct 24 from Ontario Intl. Airport to Roanoke Regional, returning Sun, Oct 25, priced at $379 found 21 hours ago
Delta
Sat, Aug 8 - Mon, Aug 10
BMI
Central Illinois Regional
ROA
Roanoke Regional
$429 Roundtrip, found 6 hours ago
$429
Roundtrip
found 6 hours ago
Select Delta flight, departing Sat, Aug 8 from Central Illinois Regional to Roanoke Regional, returning Mon, Aug 10, priced at $429 found 6 hours ago
United
Sat, Aug 8 - Tue, Aug 11
PIA
Greater Peoria Regional
ROA
Roanoke Regional
$504 Roundtrip, found 6 hours ago
$504
Roundtrip
found 6 hours ago
Select United flight, departing Sat, Aug 8 from Greater Peoria Regional to Roanoke Regional, returning Tue, Aug 11, priced at $504 found 6 hours ago
United
Wed, Oct 21 - Sat, Oct 24
CLD
McClellan-Palomar
ROA
Roanoke Regional
$600 Roundtrip, found 21 hours ago
$600
Roundtrip
found 21 hours ago
Select United flight, departing Wed, Oct 21 from McClellan-Palomar to Roanoke Regional, returning Sat, Oct 24, priced at $600 found 21 hours ago

Cheap Flights to Salem

Fall in love at first flight with your vacation to Salem by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Salem on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Salem, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Salem

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Salem with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ROA airport.

What is the cheapest month to fly to Salem?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Salem are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Salem?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Salem.

What airport is best to fly into Salem?

When you’re planning your trip to Salem, convenience is the name of the game. Luckily, Salem Roanoke Regional Airport is nearby so you can deplane and get going on checking off everything on your Salem must-do list.

How much are flights to Salem?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Salem on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $291, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Salem?

The trick to saving a stack of cash on your flight to Salem? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $291 right now, why wait?

Salem Flight Information
Destination airport
Roanoke Regional
Destination airport IATA code
ROA
Roundtrip price
$290

Last Minute Hotel Deals in Salem

Baymont by Wyndham Salem Roanoke Area

Baymont by Wyndham Salem Roanoke Area

2.5 out of 5
179 Sheraton Drive Salem VA
Book a stay at this business-friendly motel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.2/10 Good! (611 reviews)
"We were driving from TN to NJ and did not plan on staying here. We were planning on driving straight to NJ but there was a multiple crashes on I-81 and we lost close to 4 hours so we decided to stay. I quickly booked it on expedia, thinking we will just sleep and leave early morning. For the price ..."

Reviewed on Aug 3, 2026

Get rates
Baymont by Wyndham Salem Roanoke Area
avid hotel Salem by IHG

avid hotel Salem by IHG

2.5 out of 5
501 WILDWOOD ROAD Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,011 reviews)
"Very clean and a very quick check in"

Reviewed on Aug 4, 2026

Get rates
avid hotel Salem by IHG
La Quinta Inn & Suites by Wyndham Roanoke Salem

La Quinta Inn & Suites by Wyndham Roanoke Salem

3 out of 5
140 Sheraton Dr Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,393 reviews)
"Great location if traveling on I81. Goto Mac and Bobs to eat."

Reviewed on Aug 3, 2026

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La Quinta Inn & Suites by Wyndham Roanoke Salem
Fairfield Inn & Suites by Marriott Roanoke Salem

Fairfield Inn & Suites by Marriott Roanoke Salem

3 out of 5
121 Sheraton Drive Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Get rates
Fairfield Inn & Suites by Marriott Roanoke Salem
Days Inn by Wyndham Salem

Days Inn by Wyndham Salem

2 out of 5
1535 E Main St Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (353 reviews)
"It was one of the better Days Inn hotels I've ever stayed at. Staff was very helpful, accommodating to my special needs son, and very nice."

Reviewed on Aug 3, 2026

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Days Inn by Wyndham Salem
Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG

2.5 out of 5
991 Russell Dr Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,003 reviews)
"Clean room, nice staff. Good breakfast"

Reviewed on Aug 3, 2026

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Holiday Inn Express & Suites Salem by IHG
Comfort Suites Salem-Roanoke I-81

Comfort Suites Salem-Roanoke I-81

2.5 out of 5
100 Wildwood Rd Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
"Very clean with an affordable price per night. We would stay here again!"

Reviewed on Jul 27, 2026

Get rates
Comfort Suites Salem-Roanoke I-81
Quality Inn Salem - I-81

Quality Inn Salem - I-81

2.5 out of 5
151 Wildwood Rd Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Get rates
Quality Inn Salem - I-81
See all 613 properties in Salem
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Salem Roanoke Area

Baymont by Wyndham Salem Roanoke Area

2.5 out of 5
179 Sheraton Drive Salem VA
Book a stay at this business-friendly motel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.2/10 Good! (611 reviews)
"We were driving from TN to NJ and did not plan on staying here. We were planning on driving straight to NJ but there was a multiple crashes on I-81 and we lost close to 4 hours so we decided to stay. I quickly booked it on expedia, thinking we will just sleep and leave early morning. For the price ..."

Reviewed on Aug 3, 2026

Get rates
Baymont by Wyndham Salem Roanoke Area
See all 613 properties in Salem
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.