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New Madrid

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New Madrid Flights as Low as $439

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$439 Roundtrip, found 5 days ago
$439
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $439 found 5 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$469 Roundtrip, found 5 days ago
$469
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $469 found 5 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$478 Roundtrip, found 5 days ago
$478
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $478 found 5 days ago
American Airlines
Tue, Aug 19 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$485 Roundtrip, found 6 days ago
$485
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Aug 19 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $485 found 6 days ago
United
Tue, Oct 21 - Sat, Oct 25
RNO
Reno-Tahoe Intl.
JBR
Jonesboro Municipal
$488 Roundtrip, found 2 days ago
$488
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 21 from Reno-Tahoe Intl. to Jonesboro Municipal, returning Sat, Oct 25, priced at $488 found 2 days ago
United
Tue, Oct 21 - Sat, Oct 25
RNO
Reno-Tahoe Intl.
JBR
Jonesboro Municipal
$493 Roundtrip, found 2 days ago
$493
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 21 from Reno-Tahoe Intl. to Jonesboro Municipal, returning Sat, Oct 25, priced at $493 found 2 days ago
American Airlines
Tue, Aug 19 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$495 Roundtrip, found 6 days ago
$495
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Aug 19 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $495 found 6 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$500 Roundtrip, found 5 days ago
$500
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $500 found 5 days ago
American Airlines
Sat, Aug 16 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$504 Roundtrip, found 9 hours ago
$504
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $504 found 9 hours ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$506 Roundtrip, found 1 day ago
$506
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $506 found 1 day ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$509 Roundtrip, found 5 days ago
$509
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $509 found 5 days ago
American Airlines
Sat, Aug 16 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$513 Roundtrip, found 9 hours ago
$513
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $513 found 9 hours ago
American Airlines
Sat, Aug 16 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$513 Roundtrip, found 9 hours ago
$513
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $513 found 9 hours ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$515 Roundtrip, found 1 day ago
$515
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $515 found 1 day ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$515 Roundtrip, found 1 day ago
$515
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $515 found 1 day ago
United
Tue, Aug 12 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
JBR
Jonesboro Municipal
$561 Roundtrip, found 4 days ago
$561
Roundtrip
found 4 days ago
Select United flight, departing Tue, Aug 12 from Dallas-Fort Worth Intl. to Jonesboro Municipal, returning Wed, Aug 27, priced at $561 found 4 days ago

Cheap Flights to New Madrid

Fall in love at first flight with your vacation to New Madrid by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to New Madrid on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in New Madrid, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to New Madrid

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to New Madrid with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MAW airport.

What is the cheapest month to fly to New Madrid?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to New Madrid are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to New Madrid?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to New Madrid.

What airport is best to fly into New Madrid?

When you’re planning your trip to New Madrid, convenience is the name of the game. Luckily, New Madrid Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your New Madrid must-do list.

How much are flights to New Madrid?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to New Madrid on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $439, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to New Madrid?

The trick to saving a stack of cash on your flight to New Madrid? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $439 right now, why wait?

New Madrid Flight Information
Destination airport
Cape Girardeau Municipal
Destination airport IATA code
CGI
Roundtrip price
$368

Last Minute Hotel Deals in New Madrid

Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (371 reviews)
"Breakfast waffles were nice. Apples were wilting oranges were molding…. Room needed a deep clean. AC was nice and cold. Loved the large spacious room. Updated features."

Reviewed on Aug 7, 2025

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Hampton Inn Sikeston
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 out of 5
1239 Commerce Drive, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.2/10 Wonderful! (17 reviews)
"Absolutely excellent. Brand new hotel. Spotless. Staff were friendly and welcoming."

Reviewed on Jul 26, 2025

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Fairfield Inn & Suites by Marriott Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (421 reviews)
Would have been a great hotel if I felt safe
"Everything at this hotel was really nice the food was good the bed was nice the room was good the air conditioner worked good very satisfied with the overall condition and cleanliness and comfort of the room"

Reviewed on Aug 2, 2025

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Holiday Inn Express & Suites Sikeston Southwest by IHG
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61, Portageville, MO
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (679 reviews)
"Very nice stay"

Reviewed on Aug 6, 2025

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New Orleans Inn Portageville
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

2 out of 5
501 S Outer Road, Marston, MO
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
7.8/10 Good! (25 reviews)
"Perfect for weary travelers. Clean; quiet; safe; friendly night desk lady."

Reviewed on May 9, 2025

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Super 8 By Wyndham Marston
Travel Inn

Travel Inn

2.5 out of 5
301 Route Ad, Marston, MO
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
5.6/10 (106 reviews)
"The room was clean. The beds were comfortable."

Reviewed on May 25, 2025

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Travel Inn
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
8/10 Very Good! (4 reviews)
Good option for families!
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again."

Reviewed on Jul 27, 2025

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TownePlace Suites by Marriott Sikeston
Reelfoot Lake Inn

Reelfoot Lake Inn

2 out of 5
1520 State Route 21 East, Tiptonville, TN
Stay at this motel in Tiptonville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
7/10 Good! (445 reviews)
"The property was fine. The a.c. Was working but it kinda hot for me as I can’t sleep good if I’m hot. But I am hot natured. But it cooled off over into the night. But overall it was good. The price was good and the inn keeper was very nice and helpful. Could have used more shampoo and soap."

Reviewed on Jul 10, 2025

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Reelfoot Lake Inn
See all 49 properties in New Madrid
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.