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Irene

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Irene Flights as Low as $259

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Sat, Oct 25 - Sun, Oct 26
RDU
Raleigh - Durham Intl.
FSD
Sioux Falls Regional
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Oct 25 from Raleigh - Durham Intl. to Sioux Falls Regional, returning Sun, Oct 26, priced at $259 found 1 day ago
Delta
Tue, Jul 29 - Mon, Aug 4
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$259 Roundtrip, found 14 hours ago
$259
Roundtrip
found 14 hours ago
Select Delta flight, departing Tue, Jul 29 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Mon, Aug 4, priced at $259 found 14 hours ago
Delta
Mon, Jul 28 - Mon, Aug 4
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$259 Roundtrip, found 14 hours ago
$259
Roundtrip
found 14 hours ago
Select Delta flight, departing Mon, Jul 28 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Mon, Aug 4, priced at $259 found 14 hours ago
Delta
Sat, Jul 26 - Mon, Aug 4
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$264 Roundtrip, found 14 hours ago
$264
Roundtrip
found 14 hours ago
Select Delta flight, departing Sat, Jul 26 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Mon, Aug 4, priced at $264 found 14 hours ago
Delta
Sun, Jun 15 - Tue, Jun 24
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$274 Roundtrip, found 4 days ago
$274
Roundtrip
found 4 days ago
Select Delta flight, departing Sun, Jun 15 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Tue, Jun 24, priced at $274 found 4 days ago
Delta
Wed, Jun 18 - Tue, Jun 24
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$279 Roundtrip, found 4 days ago
$279
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jun 18 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Tue, Jun 24, priced at $279 found 4 days ago
Delta
Wed, May 7 - Wed, May 14
XNA
Northwest Arkansas Regional
FSD
Sioux Falls Regional
$286 Roundtrip, found 21 hours ago
$286
Roundtrip
found 21 hours ago
Select Delta flight, departing Wed, May 7 from Northwest Arkansas Regional to Sioux Falls Regional, returning Wed, May 14, priced at $286 found 21 hours ago
Delta
Tue, May 6 - Wed, May 14
XNA
Northwest Arkansas Regional
FSD
Sioux Falls Regional
$289 Roundtrip, found 21 hours ago
$289
Roundtrip
found 21 hours ago
Select Delta flight, departing Tue, May 6 from Northwest Arkansas Regional to Sioux Falls Regional, returning Wed, May 14, priced at $289 found 21 hours ago
Delta
Sat, Oct 25 - Thu, Oct 30
RDU
Raleigh - Durham Intl.
FSD
Sioux Falls Regional
$299 Roundtrip, found 1 day ago
$299
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Oct 25 from Raleigh - Durham Intl. to Sioux Falls Regional, returning Thu, Oct 30, priced at $299 found 1 day ago
Delta
Mon, May 5 - Wed, May 14
XNA
Northwest Arkansas Regional
FSD
Sioux Falls Regional
$305 Roundtrip, found 21 hours ago
$305
Roundtrip
found 21 hours ago
Select Delta flight, departing Mon, May 5 from Northwest Arkansas Regional to Sioux Falls Regional, returning Wed, May 14, priced at $305 found 21 hours ago
Delta
Thu, Jul 31 - Mon, Aug 4
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$309 Roundtrip, found 14 hours ago
$309
Roundtrip
found 14 hours ago
Select Delta flight, departing Thu, Jul 31 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Mon, Aug 4, priced at $309 found 14 hours ago
United
Sat, Jul 26 - Thu, Aug 7
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$339 Roundtrip, found 14 hours ago
$339
Roundtrip
found 14 hours ago
Select United flight, departing Sat, Jul 26 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Thu, Aug 7, priced at $339 found 14 hours ago
Delta
Tue, Jul 29 - Tue, Aug 5
VLD
Valdosta Regional
FSD
Sioux Falls Regional
$344 Roundtrip, found 23 hours ago
$344
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Jul 29 from Valdosta Regional to Sioux Falls Regional, returning Tue, Aug 5, priced at $344 found 23 hours ago
American Airlines
Tue, May 13 - Tue, May 20
HPN
Westchester County
FSD
Sioux Falls Regional
$357 Roundtrip, found 13 hours ago
$357
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, May 13 from Westchester County to Sioux Falls Regional, returning Tue, May 20, priced at $357 found 13 hours ago
Frontier Airlines
Wed, Jun 18 - Fri, Jun 20
BWI
Baltimore Washington Intl. Thurgood Marshall
FSD
Sioux Falls Regional
$461 Roundtrip, found 4 days ago
$461
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Jun 18 from Baltimore Washington Intl. Thurgood Marshall to Sioux Falls Regional, returning Fri, Jun 20, priced at $461 found 4 days ago
Frontier Airlines
Wed, Jul 30 - Fri, Aug 1
DCA
Ronald Reagan Washington National
FSD
Sioux Falls Regional
$502 Roundtrip, found 14 hours ago
$502
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Wed, Jul 30 from Ronald Reagan Washington National to Sioux Falls Regional, returning Fri, Aug 1, priced at $502 found 14 hours ago

Cheap Flights to Irene

Fall in love at first flight with your vacation to Irene by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Irene on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Irene, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Irene

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Irene with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the YKN airport.

What is the cheapest month to fly to Irene?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Irene are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Irene?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Irene.

What airport is best to fly into Irene?

When you’re planning your trip to Irene, convenience is the name of the game. Luckily, Irene Sioux Falls Regional Airport is nearby so you can deplane and get going on checking off everything on your Irene must-do list.

How much are flights to Irene?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Irene on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $259, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Irene?

The trick to saving a stack of cash on your flight to Irene? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $259 right now, why wait?

Irene Flight Information
Destination airport
Sioux Falls Regional
Destination airport IATA code
FSD
Roundtrip price
$258

Last Minute Hotel Deals in Irene

Comfort Inn Yankton SD
Comfort Inn Yankton SD
2.5 out of 5
611 W 23rd Street, Yankton, SD
The price is $122 per night from May 29 to May 30
$122
includes taxes & fees
May 29 - May 30
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (580 reviews)
Comfort Inn Yankton
"Clean throughout. Breakfast was free. Whirlpool worked and was hot as advertised. Beds are soft. Nice hotel for the price."

Reviewed on Apr 28, 2025

Comfort Inn Yankton SD
Best Western Kelly Inn
Best Western Kelly Inn
2.5 out of 5
1607 E Highway 50, Yankton, SD
The price is $117 per night from May 6 to May 7
$117
includes taxes & fees
May 6 - May 7
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (570 reviews)
"Location was good."

Reviewed on Apr 12, 2025

Best Western Kelly Inn
Fairfield Inn & Suites by Marriott Yankton
Fairfield Inn & Suites by Marriott Yankton
2.5 out of 5
508 WEST 21ST STREET, Yankton, SD
The price is $148 per night from May 4 to May 5
$148
includes taxes & fees
May 4 - May 5
Stay at this hotel in Yankton. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (119 reviews)
"Very nice and super clean!"

Reviewed on Apr 14, 2025

Fairfield Inn & Suites by Marriott Yankton
Lewis and Clark Resort
Lewis and Clark Resort
2.5 out of 5
43496 Shore Drive, Yankton, SD
The price is $122 per night from May 4 to May 5
$122
includes taxes & fees
May 4 - May 5
Book a stay at this beach hotel in Yankton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lewis and Clark Recreation Area and Midway ...
8.6/10 Excellent! (204 reviews)
"There was NO staff! I literally pulled my envelope from the wall with my last name on it. Went to turn in my key and the same thing. Just a drop box. Then they wanted me to pay for car parking. Which was just another envelope process outside. It was easy and efficient just wanted to clarify there ..."

Reviewed on Mar 4, 2025

Lewis and Clark Resort
Econo Lodge Inn & Suites
Econo Lodge Inn & Suites
2 out of 5
2410 Broadway Ave, Yankton, SD
The price is $96 per night from May 11 to May 12
$96
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fox Run Plaza and Augusta Park ...
7.2/10 Good! (636 reviews)
"Good area of town"

Reviewed on Apr 27, 2025

Econo Lodge Inn & Suites
Yankton Inn
Yankton Inn
2 out of 5
1603 East Highway 50, Yankton, SD
The price is $94 per night from May 11 to May 12
$94
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (198 reviews)
"A non-chain family run location, we took a flyer and discovered this little gem. Price point is great. As travelling snowbirds this location was convenient to our route. Check in was quick and easy. Sam was pleasant and helpful. You can tell they work hard and are slowly upgrading this facility. ..."

Reviewed on Apr 8, 2025

Yankton Inn
Super 8 by Wyndham Beresford
Super 8 by Wyndham Beresford
2 out of 5
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
The price is $64 per night from May 6 to May 7
$64
includes taxes & fees
May 6 - May 7
Book a stay at this business-friendly motel in Beresford. Enjoy free breakfast, free WiFi, and free parking.
6.2/10 (251 reviews)
"Our truck broke down on the freeway and was towed to Beresford. We asked if we could check in early and the manager said we could. We were able to check in at 12:30pm for a VERY small fee. This was extremely helpful as my husband had just had surgery and needed to rest. The staff was extremely helpful- ..."

Reviewed on Mar 14, 2025

Super 8 by Wyndham Beresford
Holiday Inn Express & Suites Yankton by IHG
Holiday Inn Express & Suites Yankton by IHG
2.5 out of 5
2607 Broadway Ave, Yankton, SD
The price is $131 per night from May 11 to May 12
$131
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (388 reviews)
"Staff was great! So helpful and friendly. Hot breakfast was so nice and complimentary welcome happy hour was a a nice surprise. I would stay again! Oh, and beds and pillows were really comfortable."

Reviewed on Apr 10, 2025

Holiday Inn Express & Suites Yankton by IHG
See all 79 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.