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Greenville

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Greenville Flights as Low as $155

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Apr 25 - Wed, May 13
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$155 Roundtrip, found 1 hour ago
$155
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sat, Apr 25 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Wed, May 13, priced at $155 found 1 hour ago
Frontier Airlines
Fri, Apr 17 - Thu, Apr 23
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$163 Roundtrip, found 21 hours ago
$163
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Fri, Apr 17 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Thu, Apr 23, priced at $163 found 21 hours ago
Frontier Airlines
Sat, Apr 25 - Fri, May 15
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$176 Roundtrip, found 1 hour ago
$176
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sat, Apr 25 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Fri, May 15, priced at $176 found 1 hour ago
Frontier Airlines
Fri, Apr 24 - Thu, Apr 30
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$180 Roundtrip, found 18 hours ago
$180
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Fri, Apr 24 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Thu, Apr 30, priced at $180 found 18 hours ago
Frontier Airlines
Sat, Apr 25 - Wed, May 13
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$182 Roundtrip, found 1 hour ago
$182
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sat, Apr 25 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Wed, May 13, priced at $182 found 1 hour ago
Frontier Airlines
Fri, Apr 17 - Thu, Apr 23
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$186 Roundtrip, found 21 hours ago
$186
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Fri, Apr 17 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Thu, Apr 23, priced at $186 found 21 hours ago
Frontier Airlines
Fri, Apr 24 - Fri, May 15
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$190 Roundtrip, found 1 day ago
$190
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Apr 24 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Fri, May 15, priced at $190 found 1 day ago
Frontier Airlines
Sun, Apr 5 - Sun, Apr 19
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$195 Roundtrip, found 1 day ago
$195
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Apr 5 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Sun, Apr 19, priced at $195 found 1 day ago
Frontier Airlines
Sun, Apr 26 - Fri, May 15
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$197 Roundtrip, found 1 hour ago
$197
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sun, Apr 26 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Fri, May 15, priced at $197 found 1 hour ago
Frontier Airlines
Tue, Jun 2 - Wed, Jun 17
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$198 Roundtrip, found 1 day ago
$198
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Jun 2 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Wed, Jun 17, priced at $198 found 1 day ago
Frontier Airlines
Thu, May 28 - Wed, Jun 17
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$203 Roundtrip, found 1 day ago
$203
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, May 28 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Wed, Jun 17, priced at $203 found 1 day ago
Frontier Airlines
Sat, Apr 25 - Wed, May 13
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$205 Roundtrip, found 1 hour ago
$205
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sat, Apr 25 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Wed, May 13, priced at $205 found 1 hour ago
United
Sat, Apr 25 - Wed, May 13
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$286 Roundtrip, found 1 hour ago
$286
Roundtrip
found 1 hour ago
Select United flight, departing Sat, Apr 25 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Wed, May 13, priced at $286 found 1 hour ago
Delta
Wed, Apr 22 - Tue, May 12
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$288 Roundtrip, found 1 hour ago
$288
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Apr 22 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Tue, May 12, priced at $288 found 1 hour ago
American Airlines
Sat, Apr 25 - Wed, May 13
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$305 Roundtrip, found 1 hour ago
$305
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Apr 25 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Wed, May 13, priced at $305 found 1 hour ago
United
Sat, Apr 18 - Sat, May 2
IAH
George Bush Intercontinental
DEC
Decatur
$343 Roundtrip, found 15 hours ago
$343
Roundtrip
found 15 hours ago
Select United flight, departing Sat, Apr 18 from George Bush Intercontinental to Decatur, returning Sat, May 2, priced at $343 found 15 hours ago

Cheap Flights to Greenville

Fall in love at first flight with your vacation to Greenville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Greenville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Greenville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Greenville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Greenville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the BLV airport.

What is the cheapest month to fly to Greenville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Greenville are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Greenville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Greenville.

What airport is best to fly into Greenville?

When you’re planning your trip to Greenville, convenience is the name of the game. Luckily, Greenville Lambert-St. Louis Intl. Airport is nearby so you can deplane and get going on checking off everything on your Greenville must-do list.

How much are flights to Greenville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Greenville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $155, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Greenville?

The trick to saving a stack of cash on your flight to Greenville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $155 right now, why wait?

Greenville Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$121

Last Minute Hotel Deals in Greenville

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

2.5 out of 5
2265 S. State Route 127 Greenville IL
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (430 reviews)
Clean and cozy

Reviewed on Mar 25, 2026

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Comfort Inn & Suites Greenville I-70
Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

2 out of 5
1700 State Route 127 Greenville IL
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (786 reviews)
This place was just OK seemed to have gotten better reviews, which is why we picked it. The rooms were just fine but a little dirty. The shower was wonderful. The breakfast was nothing but I really dislike drinking coffee out of Styrofoam cups. It was dog friendly but when I took my dog outside, ...

Reviewed on Mar 28, 2026

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Super 8 by Wyndham Greenville
SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville

2.5 out of 5
1731 S State Route 127 Greenville IL
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff ...
7.4/10 Good! (574 reviews)
Everything was good. What should be expected

Reviewed on Mar 29, 2026

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SureStay Hotel by Best Western Greenville
Budget Inn by Hotel O Greensville I 70

Budget Inn by Hotel O Greensville I 70

2 out of 5
1525 South State Rt 127 Greenville IL
Stay at this motel in Greenville. Enjoy free WiFi, free parking, and room service. Popular attractions Greenville Country Club and Patriot's Park are located ...
6.6/10 (170 reviews)
Nice place to stay Nice breakfast better than most hotels nowadays

Reviewed on Mar 30, 2026

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Budget Inn by Hotel O Greensville I 70
Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield

2.5 out of 5
1405 W Hudson Dr Litchfield IL
Book a stay at this business-friendly hotel in Litchfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,004 reviews)
The bathroom fan was hard on the ears. I could also hear my neighbors bathroom fan squealing. I was then called out of my room at 10:00pm because they didn’t run my card when I checked in.

Reviewed on Mar 29, 2026

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Baymont by Wyndham Litchfield
Seasons Inn & Suites Highland

Seasons Inn & Suites Highland

2.5 out of 5
20 Central Blvd Highland IL
Book a stay at this business-friendly hotel in Highland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (639 reviews)
Front desk staff was great, friendly and courteous. Parking was easy and close. Breakfast was the usual hotel stuff waffle maker, cereal etc.

Reviewed on Mar 30, 2026

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Seasons Inn & Suites Highland
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 out of 5
1920 Kennedy Boulevard Vandalia IL
Book a stay at this business-friendly hotel in Vandalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,002 reviews)
It's clean and it's cheaper than anything you'll get in Effingham. I've stayed here a number of times over the last ten years or so because it is perfectly situated between my home and destination. But the place is showing its age. The property desperately needs some upkeep. The rooms were refreshed ...

Reviewed on Mar 29, 2026

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Quality Inn & Suites Vandalia near I-70 and Hwy 51
Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG

2.5 out of 5
4 Thunderbird Circle Litchfield IL
Book a stay at this business-friendly hotel in Litchfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (602 reviews)
Check-in staff was excellent, accommodated my special request with courtesy and professionalism. We will be traveling to area for business over the next few months and will stay here for sure

Reviewed on Mar 29, 2026

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Holiday Inn Express & Suites Litchfield West by IHG
See all 70 properties in Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.