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East Prairie

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East Prairie Flights as Low as $360

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Mon, Aug 18 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$360 Roundtrip, found 5 days ago
$360
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Aug 18 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $360 found 5 days ago
American Airlines
Mon, Aug 18 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$366 Roundtrip, found 3 days ago
$366
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 18 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $366 found 3 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$368 Roundtrip, found 7 hours ago
$368
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $368 found 7 hours ago
American Airlines
Mon, Aug 18 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$369 Roundtrip, found 5 days ago
$369
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Aug 18 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $369 found 5 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$378 Roundtrip, found 4 days ago
$378
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $378 found 4 days ago
American Airlines
Tue, Aug 19 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$379 Roundtrip, found 5 days ago
$379
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Aug 19 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $379 found 5 days ago
American Airlines
Sat, Aug 16 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$388 Roundtrip, found 6 hours ago
$388
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $388 found 6 hours ago
American Airlines
Tue, Aug 19 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$388 Roundtrip, found 4 days ago
$388
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Aug 19 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $388 found 4 days ago
American Airlines
Mon, Aug 18 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$390 Roundtrip, found 5 days ago
$390
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Aug 18 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $390 found 5 days ago
American Airlines
Mon, Aug 18 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$392 Roundtrip, found 3 days ago
$392
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 18 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $392 found 3 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$393 Roundtrip, found 7 hours ago
$393
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $393 found 7 hours ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$394 Roundtrip, found 5 days ago
$394
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $394 found 5 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$395 Roundtrip, found 2 days ago
$395
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $395 found 2 days ago
American Airlines
Mon, Aug 18 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$396 Roundtrip, found 3 days ago
$396
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 18 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $396 found 3 days ago
American Airlines
Fri, Jul 4 - Wed, Jul 9
DTW
Detroit Metropolitan Wayne County
PAH
Barkley Regional
$415 Roundtrip, found 4 days ago
$415
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Jul 4 from Detroit Metropolitan Wayne County to Barkley Regional, returning Wed, Jul 9, priced at $415 found 4 days ago
American Airlines
Tue, Jun 17 - Thu, Jun 26
SEA
Seattle - Tacoma Intl.
PAH
Barkley Regional
$799 Roundtrip, found 1 day ago
$799
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 17 from Seattle - Tacoma Intl. to Barkley Regional, returning Thu, Jun 26, priced at $799 found 1 day ago

Cheap Flights to East Prairie

Fall in love at first flight with your vacation to East Prairie by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to East Prairie on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in East Prairie, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to East Prairie

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to East Prairie with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CGI airport.

What is the cheapest month to fly to East Prairie?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to East Prairie are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to East Prairie?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to East Prairie.

What airport is best to fly into East Prairie?

When you’re planning your trip to East Prairie, convenience is the name of the game. Luckily, East Prairie Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your East Prairie must-do list.

How much are flights to East Prairie?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to East Prairie on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $360, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to East Prairie?

The trick to saving a stack of cash on your flight to East Prairie? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $360 right now, why wait?

East Prairie Flight Information
Destination airport
Barkley Regional
Destination airport IATA code
PAH
Roundtrip price
$360

Last Minute Hotel Deals in East Prairie

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Curtains needed replaced. TV did not work at all (Dish Network) the entire night we were there. Well, the TV worked, but Dish did not, so we were not able to watch anything. Breakfast was just ok."

Reviewed on Jun 14, 2025

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Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Best hotel ever loved it"

Reviewed on Jun 7, 2025

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Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"We were there to get a good nights sleep and we did."

Reviewed on Jun 2, 2025

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Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Relaxing"

Reviewed on Jun 11, 2025

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Pear Tree Inn Sikeston
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (355 reviews)
"R"

Reviewed on Jun 2, 2025

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Hampton Inn Sikeston
Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG
2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (276 reviews)
"Everyone was very nice, we left a pair of shorts on accident and they called within 1 hour of checking to let us know that we left something. They went above and beyond trying to accommodate us. My daughter got her hand slammed in the bathroom door and the front desk gave us the closet hospital ( ..."

Reviewed on May 27, 2025

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Holiday Inn Express & Suites Union City by IHG
Quality Inn Union City US 51
Quality Inn Union City US 51
2.5 out of 5
2201 W Reelfoot Ave, Union City, TN
Stay at this hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (443 reviews)
"It was a relaxing very comfortable experience. I would definitely"

Reviewed on Jun 3, 2025

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Quality Inn Union City US 51
Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51
2.5 out of 5
1221 W Reelfoot Ave, Union City, TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (304 reviews)
"Excellent experience from check-in to check-out. The room was spotless, well-stocked with essentials, and surprisingly quiet. Front desk staft were courteous and etficient. Great value and location-highly recommend for travelers seeking a comfortable and affordable stop."

Reviewed on Jun 11, 2025

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Hospitality House Union City I 69 / US 51
See all 81 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.