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East Prairie

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Cheap Flights to East Prairie

Fall in love at first flight with your vacation to East Prairie by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to East Prairie on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in East Prairie, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to East Prairie

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to East Prairie with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CGI airport.

What is the cheapest month to fly to East Prairie?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to East Prairie are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to East Prairie?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to East Prairie.

What airport is best to fly into East Prairie?

When you’re planning your trip to East Prairie, convenience is the name of the game. Luckily, East Prairie Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your East Prairie must-do list.

How much are flights to East Prairie?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to East Prairie on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to East Prairie?

The trick to saving a stack of cash on your flight to East Prairie? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

East Prairie Flight Information
Destination airport
East Prairie
Destination airport IATA code
CGI

Last Minute Hotel Deals in East Prairie

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
Staff are wonderful, kind and welcoming! The happy hour is a great way to get out of your room and socialize. Lots of yummy food and drinks.

Reviewed on Nov 17, 2025

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
This was a really great stay, which was part of my long roadtrip. The hotel was right off the interstate & wasn't too noisy. My room was pretty big which I really enjoyed! The bed was super comfy. The front desk woman was super friendly and welcoming. I was able to get Door Dash to deliver to the ...

Reviewed on Nov 18, 2025

Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (426 reviews)
The place was nice and clean

Reviewed on Nov 17, 2025

Hampton Inn Sikeston
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

2.5 out of 5
1111 BLue Heron Lane Union City TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Discovery Park of America and ...
9/10 Wonderful! (299 reviews)
Awesome room wonderful breakfast great staff

Reviewed on Oct 31, 2025

Sleep Inn at Discovery Park of America
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
Nice room and very clean. It would be nice if they had more exercise equipment.

Reviewed on Nov 18, 2025

Pear Tree Inn Sikeston
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

2.5 out of 5
1221 W Reelfoot Ave Union City TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (358 reviews)
Easy to check in.. Clean Room..Lots of food options near by..

Reviewed on Nov 10, 2025

Hospitality House Union City I 69 / US 51
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (707 reviews)
Great value..pet friendly option..more like a 3 star.super clean

Reviewed on Nov 13, 2025

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
Friendly staff, super clean, great breakfast. What else can you ask for at this price point?

Reviewed on Nov 12, 2025

Best Western Plus Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.