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De Soto

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De Soto Flights as Low as $90

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, Oct 27 - Thu, Nov 6
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$90 Roundtrip, found 2 days ago
$90
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Oct 27 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Nov 6, priced at $90 found 2 days ago
Frontier Airlines
Thu, Nov 13 - Sun, Nov 16
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$92 Roundtrip, found 2 days ago
$92
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sun, Nov 16, priced at $92 found 2 days ago
Frontier Airlines
Fri, Oct 31 - Fri, Nov 7
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$95 Roundtrip, found 1 day ago
$95
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Oct 31 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Fri, Nov 7, priced at $95 found 1 day ago
Frontier Airlines
Fri, Nov 14 - Mon, Nov 17
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$106 Roundtrip, found 7 hours ago
$106
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Fri, Nov 14 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Mon, Nov 17, priced at $106 found 7 hours ago
Frontier Airlines
Tue, Dec 9 - Wed, Dec 10
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$126 Roundtrip, found 3 days ago
$126
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Dec 9 from Orlando Intl. to Lambert-St. Louis Intl., returning Wed, Dec 10, priced at $126 found 3 days ago
American Airlines
Tue, Nov 11 - Sat, Nov 15
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$142 Roundtrip, found 7 hours ago
$142
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Nov 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Sat, Nov 15, priced at $142 found 7 hours ago
Frontier Airlines
Fri, Oct 31 - Fri, Nov 7
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$163 Roundtrip, found 2 days ago
$163
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Oct 31 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Fri, Nov 7, priced at $163 found 2 days ago
Frontier Airlines
Fri, Oct 24 - Sat, Oct 25
AUS
Austin-Bergstrom Intl.
STL
Lambert-St. Louis Intl.
$173 Roundtrip, found 1 day ago
$173
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Oct 24 from Austin-Bergstrom Intl. to Lambert-St. Louis Intl., returning Sat, Oct 25, priced at $173 found 1 day ago
American Airlines
Fri, Nov 7 - Mon, Nov 10
SRQ
Sarasota-Bradenton Intl.
STL
Lambert-St. Louis Intl.
$190 Roundtrip, found 7 hours ago
$190
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Nov 7 from Sarasota-Bradenton Intl. to Lambert-St. Louis Intl., returning Mon, Nov 10, priced at $190 found 7 hours ago
Delta
Sat, Oct 25 - Sat, Oct 25
DAL
Love Field
STL
Lambert-St. Louis Intl.
$194 Roundtrip, found 6 days ago
$194
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Oct 25 from Love Field to Lambert-St. Louis Intl., returning Sat, Oct 25, priced at $194 found 6 days ago
Spirit Airlines
Sat, Jan 31 - Tue, Feb 3
BWI
Baltimore Washington Intl. Thurgood Marshall
STL
Lambert-St. Louis Intl.
$195 Roundtrip, found 3 days ago
$195
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Sat, Jan 31 from Baltimore Washington Intl. Thurgood Marshall to Lambert-St. Louis Intl., returning Tue, Feb 3, priced at $195 found 3 days ago
United
Sat, Dec 6 - Wed, Dec 10
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$237 Roundtrip, found 3 days ago
$237
Roundtrip
found 3 days ago
Select United flight, departing Sat, Dec 6 from Orlando Intl. to Lambert-St. Louis Intl., returning Wed, Dec 10, priced at $237 found 3 days ago
Spirit Airlines
Sat, Oct 18 - Thu, Oct 23
AUS
Austin-Bergstrom Intl.
STL
Lambert-St. Louis Intl.
$249 Roundtrip, found 4 days ago
$249
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Sat, Oct 18 from Austin-Bergstrom Intl. to Lambert-St. Louis Intl., returning Thu, Oct 23, priced at $249 found 4 days ago
Bargain Flight
Fri, Oct 24 - Tue, Oct 28
CHS
Charleston Intl.
STL
Lambert-St. Louis Intl.
$266 Roundtrip, found 1 day ago
$266
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Oct 24 from Charleston Intl. to Lambert-St. Louis Intl., returning Tue, Oct 28, priced at $266 found 1 day ago
Alaska Airlines
Fri, Nov 14 - Mon, Nov 17
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$332 Roundtrip, found 7 hours ago
$332
Roundtrip
found 7 hours ago
Select Alaska Airlines flight, departing Fri, Nov 14 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Mon, Nov 17, priced at $332 found 7 hours ago
Hawaiian Airlines
Sun, Nov 2 - Tue, Nov 4
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$440 Roundtrip, found 1 day ago
$440
Roundtrip
found 1 day ago
Select Hawaiian Airlines flight, departing Sun, Nov 2 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Tue, Nov 4, priced at $440 found 1 day ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto Spirit of St. Louis Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $90, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $90 right now, why wait?

De Soto Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$89

Last Minute Hotel Deals in De Soto

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
9.4/10 Exceptional! (153 reviews)
Breakfast
"Take the breakfast picture off the website. It said free breakfast for 2 adults but they stopped doing breakfast awhile back"

Reviewed on Sep 12, 2025

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Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Pool, Lake & Patio: Sweeping De Soto Estate

Pool, Lake & Patio: Sweeping De Soto Estate

3 out of 5
De Soto
Stay at this 3-star family-friendly cottage in De Soto. Enjoy air conditioning and an outdoor pool. Popular attractions Valle Lake Beach and Clear Lake are located ...
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Pool, Lake & Patio: Sweeping De Soto Estate
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln, Arnold, MO
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"Great easy stay. Comfortable beds , hot shower , free parking and free breakfast! Excellent staff everyone seemed super happy to be there. All around I really enjoyed it"

Reviewed on Oct 5, 2025

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Pear Tree Inn St. Louis Arnold
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,000 reviews)
"All was well.."

Reviewed on Sep 29, 2025

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Baymont Inn and Suites by Wyndham Farmington, MO
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

3 out of 5
3800 State Rt 141, Arnold, MO
Stay at this 3-star business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,009 reviews)
"The hotel staff was very helpful and friendly. The breakfast and dinner were an awesome treat."

Reviewed on Sep 30, 2025

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Drury Inn & Suites St. Louis Arnold
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

2.5 out of 5
1303 Veterans Blvd, Festus, MO
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (884 reviews)
Good place to stay, would have liked shampoo
"Good place to stay. Clean, friendly staff, fridge in room. The breakfast bar is nice. Plenty of restaurants are nearby and a Schnucks grocery store is close. My only complaint would be that I didn't see any shampoo in the bathroom or sink area. Most hotels provide shampoo. Overall, however, I enjoyed ..."

Reviewed on Sep 28, 2025

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Comfort Inn Festus - St Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3 out of 5
1001 Veterans Blvd, Festus, MO
Stay at this 3-star business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (861 reviews)
"The first night was in a room that desperately needed renovation. They moved us the second night and the room was very good."

Reviewed on Oct 2, 2025

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La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Postcard Cabins St. Francois

Postcard Cabins St. Francois

2 out of 5
7555 State Hwy Y, French Village, MO
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
9.8/10 Exceptional! (38 reviews)
"Everything was very clean and many things provided to make our stay more fun and comfortable. Staff were very nice and informative. Definitely looking forward to another stay."

Reviewed on Oct 3, 2025

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Postcard Cabins St. Francois
See all 171 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.