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Brussels

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Brussels Flights as Low as $51

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sun, Sep 6 - Mon, Sep 21
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$51 Roundtrip, found 21 hours ago
$51
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Sun, Sep 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Sep 21, priced at $51 found 21 hours ago
Frontier Airlines
Sun, Sep 6 - Fri, Sep 25
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$56 Roundtrip, found 21 hours ago
$56
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Sun, Sep 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Fri, Sep 25, priced at $56 found 21 hours ago
Frontier Airlines
Fri, Oct 30 - Thu, Nov 19
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$80 Roundtrip, found 1 day ago
$80
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Oct 30 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Nov 19, priced at $80 found 1 day ago
Frontier Airlines
Fri, Sep 11 - Wed, Sep 16
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$88 Roundtrip, found 1 day ago
$88
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Sep 11 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Sep 16, priced at $88 found 1 day ago
Southwest Airlines
Sat, Oct 31 - Sat, Oct 31
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$100 Roundtrip, found 15 hours ago
$100
Roundtrip
found 15 hours ago
Select Southwest Airlines flight, departing Sat, Oct 31 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Oct 31, priced at $100 found 15 hours ago
Delta
Sat, Oct 31 - Sat, Oct 31
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$112 Roundtrip, found 15 hours ago
$112
Roundtrip
found 15 hours ago
Select Delta flight, departing Sat, Oct 31 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Oct 31, priced at $112 found 15 hours ago
Frontier Airlines
Thu, Oct 22 - Mon, Oct 26
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$152 Roundtrip, found 18 hours ago
$152
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Thu, Oct 22 from Orlando Intl. to Lambert-St. Louis Intl., returning Mon, Oct 26, priced at $152 found 18 hours ago
American Airlines
Tue, Oct 27 - Tue, Nov 17
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$159 Roundtrip, found 9 hours ago
$159
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Oct 27 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Nov 17, priced at $159 found 9 hours ago
United
Tue, Oct 27 - Tue, Nov 17
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$170 Roundtrip, found 9 hours ago
$170
Roundtrip
found 9 hours ago
Select United flight, departing Tue, Oct 27 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Nov 17, priced at $170 found 9 hours ago
Southwest Airlines
Fri, Oct 30 - Thu, Nov 19
DAL
Love Field
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 15 hours ago
$179
Roundtrip
found 15 hours ago
Select Southwest Airlines flight, departing Fri, Oct 30 from Love Field to Lambert-St. Louis Intl., returning Thu, Nov 19, priced at $179 found 15 hours ago
Frontier Airlines
Mon, Nov 2 - Wed, Nov 4
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$199 Roundtrip, found 1 day ago
$199
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Nov 2 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Wed, Nov 4, priced at $199 found 1 day ago
Frontier Airlines
Sat, Sep 12 - Mon, Sep 14
DCA
Ronald Reagan Washington National
STL
Lambert-St. Louis Intl.
$201 Roundtrip, found 1 day ago
$201
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Sep 12 from Ronald Reagan Washington National to Lambert-St. Louis Intl., returning Mon, Sep 14, priced at $201 found 1 day ago
Frontier Airlines
Fri, Oct 23 - Fri, Nov 6
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$208 Roundtrip, found 6 days ago
$208
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Oct 23 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Fri, Nov 6, priced at $208 found 6 days ago
Southwest Airlines
Mon, Oct 5 - Fri, Oct 9
FLL
Fort Lauderdale - Hollywood Intl.
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 23 hours ago
$257
Roundtrip
found 23 hours ago
Select Southwest Airlines flight, departing Mon, Oct 5 from Fort Lauderdale - Hollywood Intl. to Lambert-St. Louis Intl., returning Fri, Oct 9, priced at $257 found 23 hours ago
American Airlines
Wed, Sep 23 - Sat, Oct 10
LBB
Preston Smith Intl.
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 23 from Preston Smith Intl. to Lambert-St. Louis Intl., returning Sat, Oct 10, priced at $257 found 1 day ago
Alaska Airlines
Mon, Aug 31 - Sun, Sep 6
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$393 Roundtrip, found 6 days ago
$393
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Mon, Aug 31 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Sun, Sep 6, priced at $393 found 6 days ago

Cheap Flights to Brussels

Fall in love at first flight with your vacation to Brussels by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Brussels on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Brussels, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Brussels

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Brussels with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Brussels?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Brussels are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Brussels?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Brussels.

What airport is best to fly into Brussels?

When you’re planning your trip to Brussels, convenience is the name of the game. Luckily, Brussels Lambert-St. Louis Intl. Airport is nearby so you can deplane and get going on checking off everything on your Brussels must-do list.

How much are flights to Brussels?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Brussels on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $51, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Brussels?

The trick to saving a stack of cash on your flight to Brussels? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $51 right now, why wait?

Brussels Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$51

Last Minute Hotel Deals in Brussels

Hollywood Casino & Hotel St. Louis

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Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

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Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (3,150 reviews)
"The staff was very helpful as my flights were delayed and it was three o'clock in the morning. By the time I got in, they were very kind and accommodating. The room was clean and well appointed. It was a great stay"

Reviewed on Aug 14, 2026

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Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

3 out of 5
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Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

3 out of 5
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Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 out of 5
1970 Craig Rd Maryland Heights MO
Stay at this hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
4.4/10 (1,002 reviews)
"this place had bugs crawling on the walls and celling the bathroom had someone nails on the floor by the tub dirty wash rags were left in the tub by past guest so that told me the room was not clean and the bathroom floor was falling in the place is old and needs to be closed to do some repairs I ..."

Reviewed on Aug 13, 2026

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Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

2 out of 5
5781 Campus Ct Hazelwood MO
Stay at this motel in Hazelwood. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions ...
8.4/10 Very Good! (2,157 reviews)
"Our bed was not clean there was someone’s left over chicken in the bed and crumbs all over the floor"

Reviewed on Aug 14, 2026

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Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

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Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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See all 575 properties in Brussels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.