Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Santa Cruz Vacations

Pack those stellar shades. We have Santa Cruz vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Santa Cruz – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Santa Cruz vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Santa Cruz

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Santa Cruz vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Santa Cruz well.

Top Hotel Deals

See all 147 Properties in Santa Cruz
Hotel Fernando III

Hotel Fernando III

San Jose 21, Seville
    4.0 out of 5.0
     
     

    This family-friendly Seville hotel is located near the airport, within a 10-minute walk of Santa Maria la Blanca Church, Alcazar, and Seville Cathedral. Giralda ...

    Hotel Fernando III$94

    Hotel Fernando III$94
    Las Casas de la Juderia

    Las Casas de la Juderia

    Calle Santa Maria La Blanca 5, Seville
      4.0 out of 5.0
       
       

      This residence consists of a labyrinth of Moorish-style houses, belonging to many different noble or popular families, and typical Spanish courtyards, interconnected ...

      Las Casas de la Juderia$103

      Las Casas de la Juderia$103
      Hotel Rey Alfonso X

      Hotel Rey Alfonso X

      Calle Ximenez De Enciso, 35, Seville
        4.0 out of 5.0
         
         

        Located in Santa Cruz, this hotel is within a 5-minute walk of Santa Maria la Blanca Church and Alcazar. Seville Cathedral and Giralda Tower are also within ...

        Hotel Rey Alfonso X$94

        Hotel Rey Alfonso X$94
        Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

        Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

        San Fernando 2, Seville
          5.0 out of 5.0
           
           

          Located in Santa Cruz, this luxury hotel is within a 5-minute walk of Plaza de Puerta Jerez and Torre del Oro Watchtower. Seville Cathedral and Alcazar are also ...

          Hotel Alfonso XIII, a Luxury Collection Hotel, Seville$317

          Hotel Alfonso XIII, a Luxury Collection Hotel, Seville$317
          EME Catedral Hotel

          EME Catedral Hotel

          Calle Alemanes 27, Seville
            5.0 out of 5.0
             
             

            Located in Santa Cruz, this luxury hotel is steps from Archiddiocesis de sevilla, Seville Cathedral, and Giralda Tower. Alcazar and Plaza de Toros de la Real ...

            EME Catedral Hotel$158

            EME Catedral Hotel$158
            Hotel Doña Maria

            Hotel Doña Maria

            Don Remondo 19, Seville
              4.0 out of 5.0
               
               

              Located in Santa Cruz, this historic hotel is steps from Archbishop's Palace, Alcazar, and Seville Cathedral. Giralda Tower and Torre del Oro Watchtower are ...

              Hotel Doña Maria$77

              Hotel Doña Maria$77
              Hotel Murillo

              Hotel Murillo

              Calle Lope de Rueda, 7-9, Seville
                2.0 out of 5.0
                 
                 

                This family-friendly Seville hotel is located near the airport, within a 5-minute walk of Murillo House, Alcazar, and Seville Cathedral. Plaza de Espana and ...

                Hotel Murillo$51

                Hotel Murillo$51
                H. Boutique Voluve

                H. Boutique Voluve

                Calle Miguel Mañara, 4, Seville
                  3.0 out of 5.0
                   
                   

                  Located in Santa Cruz, this hotel is steps from Seville Cathedral and Alcazar. Giralda Tower and Torre del Oro Watchtower are also within 10 minutes.

                  H. Boutique Voluve $48

                  H. Boutique Voluve $48
                  Hotel Alcazar

                  Hotel Alcazar

                  Avenida de Menendez Pelayo, 10, Seville
                    3.0 out of 5.0
                     
                     

                    Located in Santa Cruz, this hotel is within a 15-minute walk of Monumento a Don Juan Tenorio, Alcazar, and Plaza de Espana. Seville Cathedral and Giralda Tower ...

                    Hotel Alcazar$92

                    Hotel Alcazar$92
                    Legado Alcázar

                    Legado Alcázar

                    Calle Mariana de Pineda, 18, Seville
                      3.5 out of 5.0
                       
                       

                      Located in Santa Cruz, this hotel is within a 5-minute walk of Plaza de Puerta Jerez, Seville Cathedral, and Alcazar. Giralda Tower and Torre del Oro Watchtower ...

                      Legado Alcázar$101

                      Legado Alcázar$101