Search for Cheap Deals on
Hotels in Pythagorio

Photo by Erdem Yücel

Check Last Minute Pythagorio Hotel Deals

Tonight Oct 17 - Oct 18This weekend Oct 17 - Oct 19

Choose from 295 Pythagorio Hotel Deals

Casa Cook Samos

Casa Cook Samos

5 out of 5
Potokaki, Pythagorion, Samos
  • 4 min drive from Pythagoreion
Stay at this 5-star luxury hotel in Samos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Samos Port and Folklore Museum of Samos are ...
9.4/10 Exceptional! (92 reviews)
"Other than this being a gorgeous retreat, the staff is really top notch! They go above and beyond to make your stay comfortable. My husband’s family is from Samos, but I wanted a resort stay on the beach, and this one is gorgeous! It is close to everything, but is very quiet and secluded. We had ..."

Reviewed on Sep 20, 2025

Casa Cook Samos
Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

5 out of 5
Pythagorion, Samos, Samos Island
  • 28 min walk from Pythagoreion
Stay at this 5-star luxury hotel in Samos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Samos Port and Glicorisa Beach are located ...
9.4/10 Exceptional! (85 reviews)
"Perfect"

Reviewed on Sep 23, 2025

Proteas Blu Resort - Adults Only
Doryssa Seaside Resort

Doryssa Seaside Resort

5 out of 5
Pythagoreiou-Choras, Samos, Samos Island
  • 16 min walk from Pythagoreion
Stay at this 5-star luxury hotel in Samos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Samos Port and Potakaki beach are located ...
8.6/10 Excellent! (150 reviews)
Clean and comfortable
"Only really used the hotel for getting ready and to sleep, so can’t really comment too much. Hotel was comfortable and clean. Breakfast was good and it has a nice pool area with big comfy sunbeds. We were only there for 3 days, so spent most of our time sightseeing."

Reviewed on Jun 28, 2025

Doryssa Seaside Resort
Oceanida Bay

Oceanida Bay

3 out of 5
Pythagorio, Samos
  • 6 min drive from Pythagoreion
Stay at this 3-star hotel in Samos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Samos Port and Glicorisa Beach are located ...
5.6/10 (42 reviews)
"The place was great very nice owner and staff ate friendly. Just the location as it is not accessible to public transportation. But they can call for taxi. Beautiful island too. We enjoyed our stay here overall."

Reviewed on Aug 30, 2025

Oceanida Bay
Doryssa Boutique Hotel

Doryssa Boutique Hotel

3 out of 5
Pythagoreio, Samos, Samos Island
  • 4 min drive from Pythagoreion
Stay at this 3-star boutique hotel in Samos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Samos Port and Folklore Museum of Samos are ...
9/10 Wonderful! (15 reviews)
"-"

Reviewed on Oct 3, 2025

Doryssa Boutique Hotel
Doryssa Method Hotel

Doryssa Method Hotel

Pythagoreio, 83103, Samos, Samos
  • 5 min walk from Pythagoreion
Stay at this hotel in Samos. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Samos Port and Nikolaos Dimitriou Folklore Museum ...
9.4/10 Exceptional! (28 reviews)
"Great hotel"

Reviewed on Aug 18, 2025

Doryssa Method Hotel
Doryssa Theorem Hotel

Doryssa Theorem Hotel

4 out of 5
Pythagoreio, Samos, Samos Island
  • 5 min walk from Pythagoreion
Stay at this 4-star eco-certified hotel in Samos. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (81 reviews)
"Absolutely wonderful hotel - wish we could have stayed longer. Perfect location, beautiful room, breakfast was delicious and staff very helpful. Highly recommend."

Reviewed on Oct 8, 2025

Doryssa Theorem Hotel
Hydrele Beach Hotel

Hydrele Beach Hotel

4 out of 5
Potokaki beach, Pythagorion, Samos, Samos island
  • 29 min walk from Pythagoreion
Stay at this 4-star beach hotel in Samos. Enjoy free WiFi, an outdoor pool, and a private beach. Popular attractions Samos Port and Folklore Museum of Samos ...
8.6/10 Excellent! (39 reviews)
"Nice facilities. Very helpful and pleasant staff."

Reviewed on Sep 11, 2025

Hydrele Beach Hotel
Jimmy's apartments

Jimmy's apartments

Pythagorion, Samos, Samos
  • 6 min walk from Pythagoreion
Stay at this guesthouse in Samos. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Samos Port and Folklore Museum of the Nikolaos Dimitriou ...
4.6/10 (3 reviews)
"Tuvalet kokusu geçmedi havalandırma çok kötüydü"

Reviewed on Aug 4, 2025

Jimmy's apartments
Sunrise Hotel

Sunrise Hotel

2 out of 5
Ireon, Samos, Samos Island
  • 11 min drive from Pythagoreion
Stay at this hotel in Samos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions İreo beach and Papa Beach are located nearby.
8.4/10 Very Good! (33 reviews)
"They didn't have a room so they "upgraded " us to an apartment 50 metres away, which was nice, but we didn't have all the hotel amenities directly although they were available for us (breakfast, pool etc) All in all it was good."

Reviewed on Sep 2, 2023

Sunrise Hotel
 Doryssa Lithos Hotel

Doryssa Lithos Hotel

2 out of 5
Pythagorion, Samos
  • 9 min walk from Pythagoreion
Stay at this hotel in Samos. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Samos ...
9.6/10 Exceptional! (25 reviews)
"This property was ideally located above the port of pythagorion. Service was super friendly, staff charming with wonderful breakfasts by the pool included. They work hard to keep the property spotless and we'll maintained. Highly recommend."

Reviewed on Oct 13, 2025

Doryssa Lithos Hotel
Nisea Hotel Samos

Nisea Hotel Samos

3 out of 5
Mesokampos, Samos, Samos Island
  • 5 min drive from Pythagoreion
Stay at this 3-star hotel in Samos. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Samos Port and Glicorisa Beach are located ...
9.2/10 Wonderful! (11 reviews)
Great hotel for a short stay
"A spacious and comfortable hotel with a nice pool and staff with a friendly attitude. Fine for a short stay but rather a long way from the town which is attractive and offers lots of different places to eat especially in the evening. There’s a lovely spot for swimming in an isolated cove only five ..."

Reviewed on Jul 10, 2025

Nisea Hotel Samos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Pythagorio

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Pythagorio hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Pythagorio.

Choosing the right hotel in North Aegean Islands has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Pythagorio’s 295 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $112. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Pythagorio hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Pythagorio. No matter your reason for visiting Pythagorio, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Pythagorio hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Pythagorio for as low as $112.

How many hotels are there in Pythagorio?

With over 295 hotels in Pythagorio, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $112.

How to find cheap car rentals in Pythagorio?

Finding a cheap car rental deal in Pythagorio is as easy as scoring cheap hotels in Pythagorio. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.