Search for Cheap Deals on
Hotels in Mesopotamia

Check Last Minute Mesopotamia Hotel Deals

Tonight Nov 30 - Dec 1Next weekend Dec 5 - Dec 7

Choose from 492 Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
  • 10 hours drive from Termas de Federacion
Book a stay at this luxury hotel in Corrientes. Popular attractions Costanera de Corrientes and Cumba Cua Park are located nearby.
10/10 Exceptional! (3 reviews)
Very nice hotel

Reviewed on Nov 9, 2025

Marriott Corrientes Hotel
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

2.5 out of 5
115 3 de Febrero Gualeguaychú Entre Ríos
  • 6 hours drive from Termas de Federacion
Stay at this hotel in Gualeguaychú. Enjoy free WiFi, a 24-hour front desk, and a business center. Popular attractions Gualeguaychú Cathedral and San Martin Square ...
7.6/10 Good! (64 reviews)
Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice.

Reviewed on Jan 2, 2025

O2 Hotel Gualeguaychú
Hathor Concordia

Hathor Concordia

3 out of 5
Ruta Nacional 14-km 264.5 Concordia Entre Rios
  • 1 hour drive from Termas de Federacion
Book a stay at this business-friendly hotel in Concordia. Enjoy free breakfast, free WiFi, and room service. Popular attractions Concordia Golf Course and Castillo ...
8.6/10 Excellent! (352 reviews)
Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful.

Reviewed on Dec 31, 2024

Hathor Concordia
La Casona de Susana

La Casona de Susana

3 out of 5
3 de Febrero 448 Colon Entre Rios
  • 3 hours drive from Termas de Federacion
Book a stay at this beach hotel in Colon. Enjoy free parking, an outdoor pool, and a full-service spa. Popular attractions Termas De Colón and Colon Golf Club ...
La propietaria respeta el precio acordado. En verano si usás más de 8 horas por día el aire acondicionado te cobran un plus.

Reviewed on Mar 13, 2023

La Casona de Susana
Club Valle Termal Resort

Club Valle Termal Resort

3 out of 5
Ñandubay S/N, Corner Coronel Salas Federacion Entre Rios
  • 10 min walk from Termas de Federacion
Book a stay at this family-friendly hotel in Federacion. Enjoy free breakfast, free WiFi, and room service. Popular attractions Termas de Federacion and Termas ...
9/10 Wonderful! (94 reviews)
La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto.

Reviewed on Nov 18, 2025

Club Valle Termal Resort
Intersur Colon

Intersur Colon

3 out of 5
Av. Gdor. Quiros 185 Colón Entre Ríos
  • 3 hours drive from Termas de Federacion
Stay at this hotel in Colon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Dr. Herminio J. Quiros Park and Termas De Colón are located ...
10/10 Exceptional! (2 reviews)
Ottimo albergo
Letti molto comodi, belle piscine, personale gentile, pulizia buona, colazione buona. Ottimo rapporto qualità prezzo.

Reviewed on Aug 17, 2025

Intersur Colon
Casa del Árbol

Casa del Árbol

3 out of 5
1096 8 de Junio Concepción del Uruguay Entre Ríos
  • 4 hours drive from Termas de Federacion
Stay at this guesthouse in Concepción del Uruguay. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions Termas Concepcion Entrerios and Sala ...
8.2/10 Very Good! (8 reviews)
Very nice room in the garden. Guadalupe and her partner were very friendly and were good at providing local tips. Chilled out place to stay. Highly recommended.

Reviewed on Nov 17, 2019

Casa del Árbol
La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes

4 out of 5
Av. 3 De Abril 827 Corrientes Corrientes
  • 10 hours drive from Termas de Federacion
Book a stay at this boutique guesthouse in Corrientes. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Ciencias Naturales Amado ...
9.2/10 Wonderful! (64 reviews)
Very nice place in the middle of the city to be quiet, eat delicious, sunbathe. They should improve some minor issues to have a more than excellent stay.

Reviewed on Dec 21, 2020

La Alondra Casa De Huéspedes
Donsuites Apart Hotel

Donsuites Apart Hotel

3 out of 5
La Rioja 442 Corrientes Corrientes
  • 10 hours drive from Termas de Federacion
Stay at this aparthotel in Corrientes. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Museo de Artesanías Tradicionales Folclóricas ...
8.6/10 Excellent! (104 reviews)
Loved this place, super clean, and the staff were very nice and helpful😍

Reviewed on Aug 30, 2024

Donsuites Apart Hotel
Hotel y Spa Termas del Este

Hotel y Spa Termas del Este

3 out of 5
Presidente Raúl alfonsín 877 Federacion
  • 4 min walk from Termas de Federacion
Book a stay at this spa hotel in Federacion. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Termas Federacion Water Park and Termas de ...
8.4/10 Very Good! (12 reviews)
good for a 1 night stay

Reviewed on Aug 16, 2025

Hotel y Spa Termas del Este
Totoras Apart Federacion

Totoras Apart Federacion

2.5 out of 5
Ñandubay (ex Hermanas Betancourt) 2610 Federacion Entre Rios
  • 11 min walk from Termas de Federacion
Stay at this aparthotel in Federacion. Enjoy free WiFi, free parking, and room service. Popular attractions Termas de Federacion and Termas Federacion Water ...
Buena estadia para unos dias .todo muy limpio a pesar de que estan aun terminando dptos.tal vez deben cuidar más los horarios de descanso del turista con los ruidos de la obra . Pocos utensilios de cocina si se quiere cocinar ahi mismo.Pero tranquilo y suficiente

Reviewed on Mar 8, 2023

Totoras Apart Federacion
Holiday Inn Express Rosario by IHG

Holiday Inn Express Rosario by IHG

3 out of 5
Salta 1950 Rosario Santa Fe
  • 6 hours drive from Termas de Federacion
Book a stay at this business-friendly hotel in Rosario. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (669 reviews)
This was really a wonderful place to stay. I highly recommend it.

Reviewed on Nov 12, 2025

Holiday Inn Express Rosario by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mesopotamia

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mesopotamia hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mesopotamia.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mesopotamia’s 492 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $34. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mesopotamia hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mesopotamia. No matter your reason for visiting Mesopotamia, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mesopotamia hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mesopotamia for as low as $34.

How many hotels are there in Mesopotamia?

With over 492 hotels in Mesopotamia, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $34.

How to find cheap car rentals in Mesopotamia?

Finding a cheap car rental deal in Mesopotamia is as easy as scoring cheap hotels in Mesopotamia. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.