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Hotels in Florence

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Choose from 289 Florence Hotel Deals

Desert Reef Hot Springs

Desert Reef Hot Springs

2 out of 5
1194 Co Rd 110 Florence CO
  • 7 min drive from USP Florence ADX
Stay at this hotel in Florence. Enjoy free parking, hot springs on site, and a gift shop. Popular attractions Dakota Hot Springs and Pioneer Park are located ...
9.4/10 Exceptional! (9 reviews)
Desert Reef is a a quaint relaxing stay, soaking is very nice with shallow pools. We stayed in an Airstream our whole experience was phenomenal.

Reviewed on Sep 29, 2025

Desert Reef Hot Springs
Extended Stay America Premier Suites - Pueblo

Extended Stay America Premier Suites - Pueblo

2.5 out of 5
6020 North Elizabeth St Pueblo CO
  • 1 hour drive from USP Florence ADX
Book a stay at this business-friendly hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cinemark Tinseltown Pueblo and ...
8.8/10 Excellent! (402 reviews)
Courteous staff, clean establishment, safe surrounding, plenty of choices to eat, nearby shopping.

Reviewed on Dec 15, 2025

Extended Stay America Premier Suites - Pueblo
Days Inn by Wyndham Canon City

Days Inn by Wyndham Canon City

2 out of 5
311 Royal Gorge Blvd Canon City CO
  • 23 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,001 reviews)
The staff was very helpful. We were pleased to see the updated room decor. Nice quiet place to stay.

Reviewed on Dec 16, 2025

Days Inn by Wyndham Canon City
Holiday Inn Express & Suites Canon City by IHG

Holiday Inn Express & Suites Canon City by IHG

2.5 out of 5
3271 HWY 50 Canon City CO
  • 19 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (775 reviews)
Easy checkin, rooms very clean, friendly staff. Loved the sauna, hot tub, kids loved the swimming pool.

Reviewed on Dec 21, 2025

Holiday Inn Express & Suites Canon City by IHG
Quality Inn & Suites West

Quality Inn & Suites West

2.5 out of 5
77 South Radnor Dr Pueblo CO
  • 48 min drive from USP Florence ADX
Stay at this hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Desert ...
8.4/10 Very Good! (974 reviews)
Clean room pleasant front desk staff

Reviewed on Dec 18, 2025

Quality Inn & Suites West
Comfort Inn & Suites Pueblo

Comfort Inn & Suites Pueblo

2.5 out of 5
3910 Outlook Blvd Pueblo CO
  • 1 hour drive from USP Florence ADX
Book a stay at this business-friendly hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (898 reviews)
Courteous staff.

Reviewed on Dec 13, 2025

Comfort Inn & Suites Pueblo
Best Western Canon City

Best Western Canon City

2.5 out of 5
110 Latigo Lane Canon City CO
  • 19 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
Great place to stay!

Reviewed on Dec 7, 2025

Best Western Canon City
avid hotel Pueblo North by IHG

avid hotel Pueblo North by IHG

2 out of 5
855 Eagleridge Boulevard Pueblo CO
  • 1 hour drive from USP Florence ADX
Stay at this hotel in Pueblo. Enjoy free breakfast, free parking, and a 24-hour fitness center. Popular attractions Cinemark Tinseltown Pueblo and Greenhorn ...
9/10 Wonderful! (138 reviews)
Clean room, really like the design

Reviewed on Dec 22, 2025

avid hotel Pueblo North by IHG
Royal Gorge Cabins

Royal Gorge Cabins

3.5 out of 5
45054 West US Hwy 50 Canon City CO
  • 36 min drive from USP Florence ADX
Stay at this cabin in Canon City. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Royal Gorge Bridge and Tunnel Drive are located ...
9.6/10 Exceptional! (246 reviews)
The cabin was wonderful and the views were amazing!

Reviewed on Dec 17, 2025

Royal Gorge Cabins
Budget Host Royal Gorge Inn

Budget Host Royal Gorge Inn

2 out of 5
217 N Raynolds Ave Canon City CO
  • 21 min drive from USP Florence ADX
Stay at this motel in Canon City. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (326 reviews)
The room was spotless as usual! We always love seeing David! He is super kind and polite! We stay here everytime we are in town!

Reviewed on Dec 14, 2025

Budget Host Royal Gorge Inn
Hampton Inn & Suites Pueblo/North

Hampton Inn & Suites Pueblo/North

2.5 out of 5
4790 Eagleridge Circle Pueblo CO
  • 1 hour drive from USP Florence ADX
Stay at this hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Cinemark ...
8.6/10 Excellent! (1,004 reviews)
We had an early medical appointment and the accommodations were pleasant. Easy check in and check out. No surprises. Good location. Breakfast was good, fresh, and ready

Reviewed on Dec 18, 2025

Hampton Inn & Suites Pueblo/North
Hampton Inn Canon City

Hampton Inn Canon City

2.5 out of 5
102 Mccormick Pkwy Canon City CO
  • 19 min drive from USP Florence ADX
Stay at this hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,000 reviews)
Clean comfortable room. Unfortunately no hot breakfast due to broken oven, but yogurt and bagels were good.

Reviewed on Oct 11, 2025

Hampton Inn Canon City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florence

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