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Serena

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Serena Flights as Low as $178

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
Sat, Aug 30 - Sun, Aug 31
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$178 Roundtrip, found 23 hours ago
$178
Roundtrip
found 23 hours ago
Select Bargain Flight flight, departing Sat, Aug 30 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sun, Aug 31, priced at $178 found 23 hours ago
Alaska Airlines
Sat, Aug 30 - Sun, Aug 31
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$182 Roundtrip, found 23 hours ago
$182
Roundtrip
found 23 hours ago
Select Alaska Airlines flight, departing Sat, Aug 30 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sun, Aug 31, priced at $182 found 23 hours ago
Delta
Sat, Aug 30 - Sun, Aug 31
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$182 Roundtrip, found 23 hours ago
$182
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Aug 30 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sun, Aug 31, priced at $182 found 23 hours ago
American Airlines
Sat, Aug 30 - Sun, Aug 31
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$182 Roundtrip, found 23 hours ago
$182
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Sat, Aug 30 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sun, Aug 31, priced at $182 found 23 hours ago
Bargain Flight
Wed, Aug 27 - Sun, Aug 31
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$183 Roundtrip, found 15 hours ago
$183
Roundtrip
found 15 hours ago
Select Bargain Flight flight, departing Wed, Aug 27 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sun, Aug 31, priced at $183 found 15 hours ago
Hawaiian Airlines
Sat, Aug 30 - Wed, Sep 3
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$184 Roundtrip, found 3 days ago
$184
Roundtrip
found 3 days ago
Select Hawaiian Airlines flight, departing Sat, Aug 30 from Seattle - Tacoma Intl. to O'Hare Intl., returning Wed, Sep 3, priced at $184 found 3 days ago
Alaska Airlines
Sat, Sep 20 - Sat, Sep 20
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$187 Roundtrip, found 4 days ago
$187
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Sat, Sep 20 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sat, Sep 20, priced at $187 found 4 days ago
Hawaiian Airlines
Tue, Aug 26 - Sun, Aug 31
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$187 Roundtrip, found 3 days ago
$187
Roundtrip
found 3 days ago
Select Hawaiian Airlines flight, departing Tue, Aug 26 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sun, Aug 31, priced at $187 found 3 days ago
United
Wed, Aug 27 - Sun, Aug 31
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$187 Roundtrip, found 15 hours ago
$187
Roundtrip
found 15 hours ago
Select United flight, departing Wed, Aug 27 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sun, Aug 31, priced at $187 found 15 hours ago
Frontier Airlines
Wed, Aug 27 - Sat, Aug 30
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$252 Roundtrip, found 22 hours ago
$252
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Wed, Aug 27 from Seattle - Tacoma Intl. to O'Hare Intl., returning Sat, Aug 30, priced at $252 found 22 hours ago
Frontier Airlines
Thu, Aug 14 - Sat, Aug 16
SEA
Seattle - Tacoma Intl.
MDW
Midway Intl.
$263 Roundtrip, found 4 days ago
$263
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Aug 14 from Seattle - Tacoma Intl. to Midway Intl., returning Sat, Aug 16, priced at $263 found 4 days ago
Frontier Airlines
Fri, Aug 22 - Mon, Aug 25
PAE
Seattle Paine Field Intl. Airport
ORD
O'Hare Intl.
$268 Roundtrip, found 19 hours ago
$268
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Fri, Aug 22 from Seattle Paine Field Intl. Airport to O'Hare Intl., returning Mon, Aug 25, priced at $268 found 19 hours ago
Spirit Airlines
Fri, Aug 8 - Mon, Aug 11
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$269 Roundtrip, found 3 days ago
$269
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Fri, Aug 8 from Seattle - Tacoma Intl. to O'Hare Intl., returning Mon, Aug 11, priced at $269 found 3 days ago
American Airlines
Wed, Dec 17 - Sat, Jan 10
SEA
Seattle - Tacoma Intl.
PIA
Greater Peoria Regional
$342 Roundtrip, found 1 day ago
$342
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Dec 17 from Seattle - Tacoma Intl. to Greater Peoria Regional, returning Sat, Jan 10, priced at $342 found 1 day ago
JetBlue Airways
Tue, Oct 21 - Wed, Oct 22
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$377 Roundtrip, found 6 days ago
$377
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Tue, Oct 21 from Seattle - Tacoma Intl. to O'Hare Intl., returning Wed, Oct 22, priced at $377 found 6 days ago
Sun Country Airlines
Fri, Aug 8 - Mon, Aug 11
SEA
Seattle - Tacoma Intl.
ORD
O'Hare Intl.
$495 Roundtrip, found 3 days ago
$495
Roundtrip
found 3 days ago
Select Sun Country Airlines flight, departing Fri, Aug 8 from Seattle - Tacoma Intl. to O'Hare Intl., returning Mon, Aug 11, priced at $495 found 3 days ago

Cheap Flights to Serena

Fall in love at first flight with your vacation to Serena by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Serena on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Serena, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Serena

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Serena with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the VYS airport.

What is the cheapest month to fly to Serena?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Serena are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Serena?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Serena.

What airport is best to fly into Serena?

When you’re planning your trip to Serena, convenience is the name of the game. Luckily, Serena Dupage Airport is nearby so you can deplane and get going on checking off everything on your Serena must-do list.

How much are flights to Serena?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Serena on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $178, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Serena?

The trick to saving a stack of cash on your flight to Serena? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $178 right now, why wait?

Serena Flight Information
Destination airport
O'Hare Intl.
Destination airport IATA code
ORD
Roundtrip price
$72

Last Minute Hotel Deals in Serena

Grand Bear Resort at Starved Rock

Grand Bear Resort at Starved Rock

3 out of 5
2643 IL-178, Utica, IL
Stay at this 3-star golf hotel in Utica. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (879 reviews)
"The property is older but clean and in good condition. The main building of the resort houses the water park, cafe’, bar and restaurant and the ‘hotel’ style rooms. The room we had was upstairs and over looked what was a volleyball court. This looked like it needed some work or grass laid around ..."

Reviewed on Jul 30, 2025

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Grand Bear Resort at Starved Rock
Holiday Inn Express & Suites Yorkville by IHG

Holiday Inn Express & Suites Yorkville by IHG

2.5 out of 5
577 E KENDALL DRIVE, Yorkville, IL
Book a stay at this spa hotel in Yorkville. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (569 reviews)
"Everything was good except for them running out of food at breakfast. Staff was friendly. Facility was clean. Room was comfortable."

Reviewed on Jul 31, 2025

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Holiday Inn Express & Suites Yorkville by IHG
Best Western Oglesby Inn

Best Western Oglesby Inn

2.5 out of 5
900 Holiday Street, Oglesby, IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
8/10 Very Good! (1,001 reviews)
"The microwave got stuck shut and held my coffee hostage, so I had to get someone to come to the room and get it open. Otherwise, the room was clean and comfortable, and quiet."

Reviewed on Jul 26, 2025

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Best Western Oglesby Inn
Postcard Cabins Starved Rock

Postcard Cabins Starved Rock

2 out of 5
1879 N 2703rd Rd, Ottawa, IL
Stay at this cabin in Ottawa. Enjoy free parking, patios, and climate control. Popular attractions Tangled Roots Brewing Company - The Lone Buffalo and Washington ...
10/10 Exceptional! (40 reviews)
"There were ants inside of the cabin. The floors were dirty upon entry and the ants made sleeping difficult. The bottom step going up into the cabin was also broken, creating a tripping hazard."

Reviewed on Jul 20, 2025

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Postcard Cabins Starved Rock
Comfort Inn Ottawa Starved Rock Area

Comfort Inn Ottawa Starved Rock Area

2.5 out of 5
120 W. Stevenson Road, Ottawa, IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (679 reviews)
"Nice & ok but glass door didn’t lock for safety, elevator broken , had to use steps , gabage outside overflowing outside hotel . But breakfast buffet was great 5 stars !"

Reviewed on Jul 25, 2025

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Comfort Inn Ottawa Starved Rock Area
Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG

Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG

3.5 out of 5
2558 N 3653 Road, Sheridan, IL
Stay at this 3.5-star golf aparthotel in Sheridan. Enjoy free parking, an outdoor pool, and a golf course. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (560 reviews)
"We absolutely love coming to stay at this property! The indoor and outdoor pools are so refreshing! The rooms are spacious and we always utilize the kitchen and balcony. While on our last visit we were so saddened to hear that this resort is closing! I believe October 2 is their last checkout date😭 ..."

Reviewed on Jul 23, 2025

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Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
Days Inn by Wyndham Oglesby/ Starved Rock

Days Inn by Wyndham Oglesby/ Starved Rock

2 out of 5
120 N Lewis Ave, Oglesby, IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,000 reviews)
"This property and stay was average"

Reviewed on Jul 27, 2025

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Days Inn by Wyndham Oglesby/ Starved Rock
Days Inn & Suites by Wyndham of Morris

Days Inn & Suites by Wyndham of Morris

2 out of 5
80 Hampton Road, Morris, IL
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
6.8/10 (822 reviews)
"Great hotel for price! Clean good beds only down fall little for breakfast"

Reviewed on Jul 17, 2025

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Days Inn & Suites by Wyndham of Morris
See all 340 properties in Serena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.