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Serena

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Serena Flights as Low as $69

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Apr 29 - Wed, Apr 29
ATL
Hartsfield-Jackson Atlanta Intl.
ORD
O'Hare Intl.
$69 Roundtrip, found 2 hours ago
$69
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Wed, Apr 29 from Hartsfield-Jackson Atlanta Intl. to O'Hare Intl., returning Wed, Apr 29, priced at $69 found 2 hours ago
Frontier Airlines
Wed, Apr 8 - Tue, Apr 21
ATL
Hartsfield-Jackson Atlanta Intl.
MDW
Midway Intl.
$72 Roundtrip, found 4 days ago
$72
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Apr 8 from Hartsfield-Jackson Atlanta Intl. to Midway Intl., returning Tue, Apr 21, priced at $72 found 4 days ago
Spirit Airlines
Tue, May 12 - Sat, May 16
DFW
Dallas-Fort Worth Intl.
ORD
O'Hare Intl.
$74 Roundtrip, found 16 hours ago
$74
Roundtrip
found 16 hours ago
Select Spirit Airlines flight, departing Tue, May 12 from Dallas-Fort Worth Intl. to O'Hare Intl., returning Sat, May 16, priced at $74 found 16 hours ago
Frontier Airlines
Thu, Apr 23 - Tue, May 5
DFW
Dallas-Fort Worth Intl.
MDW
Midway Intl.
$78 Roundtrip, found 1 day ago
$78
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Apr 23 from Dallas-Fort Worth Intl. to Midway Intl., returning Tue, May 5, priced at $78 found 1 day ago
Bargain Flight
Sat, May 16 - Sat, May 16
ATL
Hartsfield-Jackson Atlanta Intl.
ORD
O'Hare Intl.
$165 Roundtrip, found 4 hours ago
$165
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Sat, May 16 from Hartsfield-Jackson Atlanta Intl. to O'Hare Intl., returning Sat, May 16, priced at $165 found 4 hours ago
Delta
Sat, May 2 - Sat, May 9
DAL
Love Field
MDW
Midway Intl.
$180 Roundtrip, found 5 days ago
$180
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, May 2 from Love Field to Midway Intl., returning Sat, May 9, priced at $180 found 5 days ago
Delta
Tue, May 5 - Wed, May 6
DAL
Love Field
ORD
O'Hare Intl.
$201 Roundtrip, found 1 day ago
$201
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 5 from Love Field to O'Hare Intl., returning Wed, May 6, priced at $201 found 1 day ago
American Airlines
Mon, Apr 27 - Fri, May 1
ATL
Hartsfield-Jackson Atlanta Intl.
RFD
Greater Rockford
$216 Roundtrip, found 1 day ago
$216
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 27 from Hartsfield-Jackson Atlanta Intl. to Greater Rockford, returning Fri, May 1, priced at $216 found 1 day ago
Bargain Flight
Fri, May 15 - Mon, May 18
PBI
Palm Beach Intl.
ORD
O'Hare Intl.
$235 Roundtrip, found 5 days ago
$235
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Fri, May 15 from Palm Beach Intl. to O'Hare Intl., returning Mon, May 18, priced at $235 found 5 days ago
American Airlines
Thu, Apr 16 - Sun, Apr 19
PBI
Palm Beach Intl.
RFD
Greater Rockford
$287 Roundtrip, found 18 hours ago
$287
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Thu, Apr 16 from Palm Beach Intl. to Greater Rockford, returning Sun, Apr 19, priced at $287 found 18 hours ago
Delta
Fri, Jun 19 - Tue, Jun 23
PBI
Palm Beach Intl.
MDW
Midway Intl.
$309 Roundtrip, found 16 hours ago
$309
Roundtrip
found 16 hours ago
Select Delta flight, departing Fri, Jun 19 from Palm Beach Intl. to Midway Intl., returning Tue, Jun 23, priced at $309 found 16 hours ago
American Airlines
Fri, Apr 10 - Tue, Apr 14
DFW
Dallas-Fort Worth Intl.
RFD
Greater Rockford
$310 Roundtrip, found 16 hours ago
$310
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Fri, Apr 10 from Dallas-Fort Worth Intl. to Greater Rockford, returning Tue, Apr 14, priced at $310 found 16 hours ago
United
Sat, Jun 13 - Wed, Jun 17
DFW
Dallas-Fort Worth Intl.
PIA
Greater Peoria Regional
$362 Roundtrip, found 1 hour ago
$362
Roundtrip
found 1 hour ago
Select United flight, departing Sat, Jun 13 from Dallas-Fort Worth Intl. to Greater Peoria Regional, returning Wed, Jun 17, priced at $362 found 1 hour ago
Delta
Wed, May 27 - Sat, Jun 13
ATL
Hartsfield-Jackson Atlanta Intl.
BMI
Central Illinois Regional
$419 Roundtrip, found 6 days ago
$419
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, May 27 from Hartsfield-Jackson Atlanta Intl. to Central Illinois Regional, returning Sat, Jun 13, priced at $419 found 6 days ago
American Airlines
Sat, Mar 21 - Wed, Mar 25
DFW
Dallas-Fort Worth Intl.
BMI
Central Illinois Regional
$507 Roundtrip, found 1 day ago
$507
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Mar 21 from Dallas-Fort Worth Intl. to Central Illinois Regional, returning Wed, Mar 25, priced at $507 found 1 day ago
Delta
Wed, Mar 18 - Wed, Mar 25
DAL
Love Field
BMI
Central Illinois Regional
$521 Roundtrip, found 2 days ago
$521
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Mar 18 from Love Field to Central Illinois Regional, returning Wed, Mar 25, priced at $521 found 2 days ago

Cheap Flights to Serena

Fall in love at first flight with your vacation to Serena by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Serena on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Serena, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Serena

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Serena with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the VYS airport.

What is the cheapest month to fly to Serena?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Serena are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Serena?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Serena.

What airport is best to fly into Serena?

When you’re planning your trip to Serena, convenience is the name of the game. Luckily, Serena Dupage Airport is nearby so you can deplane and get going on checking off everything on your Serena must-do list.

How much are flights to Serena?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Serena on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $69, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Serena?

The trick to saving a stack of cash on your flight to Serena? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $69 right now, why wait?

Serena Flight Information
Destination airport
O'Hare Intl.
Destination airport IATA code
ORD
Roundtrip price
$74

Last Minute Hotel Deals in Serena

Grand Bear Resort at Starved Rock

Grand Bear Resort at Starved Rock

3 out of 5
2643 IL-178 Utica IL
Book a stay at this golf hotel in Utica. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.4/10 Good! (1,002 reviews)
Everything was closed.

Reviewed on Mar 13, 2026

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Grand Bear Resort at Starved Rock
Postcard Cabins Starved Rock, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Starved Rock, Outdoor Collection by Marriott Bonvoy

2 out of 5
1879 N 2703rd Rd Ottawa IL
Stay at this cabin in Ottawa. Enjoy free parking, patios, and climate control. Popular attractions Tangled Roots Brewing Company - The Lone Buffalo and Washington ...
9.8/10 Exceptional! (137 reviews)
Great experience!

Reviewed on Mar 9, 2026

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Postcard Cabins Starved Rock, Outdoor Collection by Marriott Bonvoy
Holiday Inn Express & Suites Yorkville by IHG

Holiday Inn Express & Suites Yorkville by IHG

2.5 out of 5
577 E KENDALL DRIVE Yorkville IL
Book a stay at this spa hotel in Yorkville. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (667 reviews)
My girlfriend and I are both local and we’re five minutes from our house. The only reason we rented their room was for my girlfriend‘s birthday. To lay around and be lazy and sit in the hot tub. The hot tub was not working when we got down there. I told the guy sitting at the front desk. He told ...

Reviewed on Mar 8, 2026

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Holiday Inn Express & Suites Yorkville by IHG
Days Inn by Wyndham Oglesby/ Starved Rock

Days Inn by Wyndham Oglesby/ Starved Rock

2 out of 5
120 N Lewis Ave Oglesby IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
This hotel is a perfect place after a long day on the road. They are very friendly and helpful. Has a full hot waffle breakfast.

Reviewed on Mar 3, 2026

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Days Inn by Wyndham Oglesby/ Starved Rock
Days Inn & Suites by Wyndham Morris/I-80

Days Inn & Suites by Wyndham Morris/I-80

2 out of 5
80 Hampton Road Morris IL
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
7/10 Good! (893 reviews)
The room was clean and on the 1st floor and I was able to park car in front of my room window. Bed was comfortable and sufficient comfy pillows. Loved the zero walk in shower with handicapped bars on 3 sides. Room was large and comfy with Refrigerator & ice maker close to the room. Breakfast was ...

Reviewed on Mar 10, 2026

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Days Inn & Suites by Wyndham Morris/I-80
Comfort Inn Morris I-80

Comfort Inn Morris I-80

2.5 out of 5
70 Gore Rd Morris IL
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Get rates
Comfort Inn Morris I-80
Best Western Oglesby Inn

Best Western Oglesby Inn

2.5 out of 5
900 Holiday Street Oglesby IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,001 reviews)
Eselente hotel muy guen servicio

Reviewed on Mar 7, 2026

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Best Western Oglesby Inn
Hampton Inn Yorkville

Hampton Inn Yorkville

2.5 out of 5
310 East Countryside Parkway Yorkville IL
Book a stay at this business-friendly hotel in Yorkville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (920 reviews)
Rooms and common areas clean, comfortable, friendly staff. Brkfst selection/food was great! No probs, parking was good. Will stay here again when in Chi area.

Reviewed on Mar 4, 2026

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Hampton Inn Yorkville
See all 275 properties in Serena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.