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Serena

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Serena Flights as Low as $112

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Sat, Aug 9 - Wed, Aug 13
IAH
George Bush Intercontinental
ORD
O'Hare Intl.
$112 Roundtrip, just found
$112
Roundtrip
just found
Select Spirit Airlines flight, departing Sat, Aug 9 from George Bush Intercontinental to O'Hare Intl., returning Wed, Aug 13, priced at $112 just found
Spirit Airlines
Fri, Sep 5 - Mon, Sep 8
DFW
Dallas-Fort Worth Intl.
ORD
O'Hare Intl.
$120 Roundtrip, just found
$120
Roundtrip
just found
Select Spirit Airlines flight, departing Fri, Sep 5 from Dallas-Fort Worth Intl. to O'Hare Intl., returning Mon, Sep 8, priced at $120 just found
Frontier Airlines
Mon, Sep 22 - Fri, Sep 26
IAH
George Bush Intercontinental
ORD
O'Hare Intl.
$131 Roundtrip, found 15 hours ago
$131
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Mon, Sep 22 from George Bush Intercontinental to O'Hare Intl., returning Fri, Sep 26, priced at $131 found 15 hours ago
American Airlines
Sat, Aug 16 - Tue, Aug 19
CLT
Charlotte-Douglas Intl.
ORD
O'Hare Intl.
$141 Roundtrip, found 21 hours ago
$141
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Charlotte-Douglas Intl. to O'Hare Intl., returning Tue, Aug 19, priced at $141 found 21 hours ago
United
Sat, Aug 16 - Tue, Aug 19
CLT
Charlotte-Douglas Intl.
ORD
O'Hare Intl.
$141 Roundtrip, found 21 hours ago
$141
Roundtrip
found 21 hours ago
Select United flight, departing Sat, Aug 16 from Charlotte-Douglas Intl. to O'Hare Intl., returning Tue, Aug 19, priced at $141 found 21 hours ago
Frontier Airlines
Sat, Aug 2 - Sat, Aug 9
DFW
Dallas-Fort Worth Intl.
MDW
Midway Intl.
$172 Roundtrip, just found
$172
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Aug 2 from Dallas-Fort Worth Intl. to Midway Intl., returning Sat, Aug 9, priced at $172 just found
Contour Airlines
Mon, Aug 25 - Thu, Aug 28
DFW
Dallas-Fort Worth Intl.
ORD
O'Hare Intl.
$189 Roundtrip, just found
$189
Roundtrip
just found
Select Contour Airlines flight, departing Mon, Aug 25 from Dallas-Fort Worth Intl. to O'Hare Intl., returning Thu, Aug 28, priced at $189 just found
Delta
Sat, Aug 30 - Sun, Aug 31
CLT
Charlotte-Douglas Intl.
MDW
Midway Intl.
$197 Roundtrip, found 5 days ago
$197
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Aug 30 from Charlotte-Douglas Intl. to Midway Intl., returning Sun, Aug 31, priced at $197 found 5 days ago
Delta
Tue, Sep 9 - Tue, Sep 9
DAL
Love Field
ORD
O'Hare Intl.
$201 Roundtrip, just found
$201
Roundtrip
just found
Select Delta flight, departing Tue, Sep 9 from Love Field to O'Hare Intl., returning Tue, Sep 9, priced at $201 just found
Delta
Sat, Sep 6 - Tue, Sep 9
DAL
Love Field
MDW
Midway Intl.
$202 Roundtrip, just found
$202
Roundtrip
just found
Select Delta flight, departing Sat, Sep 6 from Love Field to Midway Intl., returning Tue, Sep 9, priced at $202 just found
Delta
Tue, Sep 30 - Thu, Oct 2
IAH
George Bush Intercontinental
MDW
Midway Intl.
$227 Roundtrip, found 23 hours ago
$227
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Sep 30 from George Bush Intercontinental to Midway Intl., returning Thu, Oct 2, priced at $227 found 23 hours ago
Bargain Flight
Tue, Aug 19 - Tue, Aug 26
DFW
Dallas-Fort Worth Intl.
PIA
Greater Peoria Regional
$227 Roundtrip, found 4 hours ago
$227
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Tue, Aug 19 from Dallas-Fort Worth Intl. to Greater Peoria Regional, returning Tue, Aug 26, priced at $227 found 4 hours ago
American Airlines
Fri, Jul 11 - Sat, Jul 12
IAH
George Bush Intercontinental
PIA
Greater Peoria Regional
$253 Roundtrip, found 12 hours ago
$253
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Fri, Jul 11 from George Bush Intercontinental to Greater Peoria Regional, returning Sat, Jul 12, priced at $253 found 12 hours ago
Bargain Flight
Thu, Jul 31 - Wed, Aug 6
CLT
Charlotte-Douglas Intl.
PIA
Greater Peoria Regional
$298 Roundtrip, found 1 day ago
$298
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Jul 31 from Charlotte-Douglas Intl. to Greater Peoria Regional, returning Wed, Aug 6, priced at $298 found 1 day ago
American Airlines
Mon, Jun 30 - Sun, Jul 6
DFW
Dallas-Fort Worth Intl.
BMI
Central Illinois Regional
$528 Roundtrip, found 4 days ago
$528
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Jun 30 from Dallas-Fort Worth Intl. to Central Illinois Regional, returning Sun, Jul 6, priced at $528 found 4 days ago
Delta
Thu, Jul 3 - Sun, Jul 6
DAL
Love Field
BMI
Central Illinois Regional
$867 Roundtrip, found 4 days ago
$867
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jul 3 from Love Field to Central Illinois Regional, returning Sun, Jul 6, priced at $867 found 4 days ago

Cheap Flights to Serena

Fall in love at first flight with your vacation to Serena by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Serena on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Serena, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Serena

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Serena with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the VYS airport.

What is the cheapest month to fly to Serena?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Serena are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Serena?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Serena.

What airport is best to fly into Serena?

When you’re planning your trip to Serena, convenience is the name of the game. Luckily, Serena Dupage Airport is nearby so you can deplane and get going on checking off everything on your Serena must-do list.

How much are flights to Serena?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Serena on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $112, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Serena?

The trick to saving a stack of cash on your flight to Serena? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $112 right now, why wait?

Serena Flight Information
Destination airport
O'Hare Intl.
Destination airport IATA code
ORD
Roundtrip price
$128

Last Minute Hotel Deals in Serena

Grand Bear Resort at Starved Rock
Grand Bear Resort at Starved Rock
3 out of 5
2643 IL-178, Utica, IL
Stay at this 3-star golf hotel in Utica. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (827 reviews)
"There is so much do here! I love that it is out of any city limits. You dont need to leave, they have everything you may need. Live music Friday and Saturday! 2 types of eateries. My son and I even got to watch a movie friday night! Totally worth it!"

Reviewed on Jun 15, 2025

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Grand Bear Resort at Starved Rock
Best Western Oglesby Inn
Best Western Oglesby Inn
2.5 out of 5
900 Holiday Street, Oglesby, IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
8/10 Very Good! (1,001 reviews)
"The breakfast was nice. Room was large and comfortable. Price reasonable and location very good."

Reviewed on Jun 10, 2025

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Best Western Oglesby Inn
Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
3.5 out of 5
2558 N 3653 Road, Sheridan, IL
Stay at this 3.5-star golf aparthotel in Sheridan. Enjoy free parking, an outdoor pool, and a golf course. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (527 reviews)
"Overall trip was good furnishings could be updated. Only problem we had was no hot water a few of the days. One day it was cold in the afternoon but then in the morning we got hot water back and then no hot water for the next day and a half."

Reviewed on Jun 13, 2025

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Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
Comfort Inn Morris I-80
Comfort Inn Morris I-80
2.5 out of 5
70 Gore Rd, Morris, IL
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (557 reviews)
"It was nice and da bed was comfortable"

Reviewed on Jun 16, 2025

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Comfort Inn Morris I-80
Super 8 by Wyndham Ottawa Starved Rock
Super 8 by Wyndham Ottawa Starved Rock
2 out of 5
500 East Etna Rd., Ottawa, IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,000 reviews)
"Standard super 8 but was quiet and clean"

Reviewed on Jun 6, 2025

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Super 8 by Wyndham Ottawa Starved Rock
Days Inn by Wyndham Oglesby/ Starved Rock
Days Inn by Wyndham Oglesby/ Starved Rock
2 out of 5
120 N Lewis Ave, Oglesby, IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,001 reviews)
"Everything was good"

Reviewed on Jun 6, 2025

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Days Inn by Wyndham Oglesby/ Starved Rock
Holiday Inn Express & Suites Ottawa by IHG
Holiday Inn Express & Suites Ottawa by IHG
2.5 out of 5
2850 Columbus Street, Ottawa, IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (466 reviews)
"Newer property. Everything was in great condition. Lots of breakfast options and friendly service."

Reviewed on Jun 15, 2025

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Holiday Inn Express & Suites Ottawa by IHG
Comfort Inn Ottawa Starved Rock Area
Comfort Inn Ottawa Starved Rock Area
2.5 out of 5
120 W. Stevenson Road, Ottawa, IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (654 reviews)
"Nice basic hotel with decent breakfast"

Reviewed on Jun 8, 2025

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Comfort Inn Ottawa Starved Rock Area
See all 337 properties in Serena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.