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Santa Clara

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Santa Clara Flights as Low as $250

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$250 Roundtrip, found 1 hour ago
$250
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $250 found 1 hour ago
Copa
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$268 Roundtrip, found 1 hour ago
$268
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $268 found 1 hour ago
Copa
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$285 Roundtrip, found 1 hour ago
$285
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $285 found 1 hour ago
avianca
Sat, Jul 11 - Tue, Jul 21
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$293 Roundtrip, found 14 hours ago
$293
Roundtrip
found 14 hours ago
Select avianca flight, departing Sat, Jul 11 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Jul 21, priced at $293 found 14 hours ago
avianca
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$296 Roundtrip, found 1 hour ago
$296
Roundtrip
found 1 hour ago
Select avianca flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $296 found 1 hour ago
Copa
Mon, Jun 8 - Mon, Jun 15
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$300 Roundtrip, found 5 days ago
$300
Roundtrip
found 5 days ago
Select Copa flight, departing Mon, Jun 8 from Juan Santamaría Intl. to Tocumen Intl., returning Mon, Jun 15, priced at $300 found 5 days ago
Copa
Thu, Jun 11 - Sun, Jun 14
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$301 Roundtrip, found 5 days ago
$301
Roundtrip
found 5 days ago
Select Copa flight, departing Thu, Jun 11 from Juan Santamaría Intl. to Tocumen Intl., returning Sun, Jun 14, priced at $301 found 5 days ago
Copa
Thu, Aug 13 - Mon, Aug 17
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$303 Roundtrip, found 10 hours ago
$303
Roundtrip
found 10 hours ago
Select Copa flight, departing Thu, Aug 13 from Juan Santamaría Intl. to Tocumen Intl., returning Mon, Aug 17, priced at $303 found 10 hours ago
United
Tue, Aug 18 - Wed, Sep 2
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$565 Roundtrip, found 1 day ago
$565
Roundtrip
found 1 day ago
Select United flight, departing Tue, Aug 18 from Austin-Bergstrom Intl. to Tocumen Intl., returning Wed, Sep 2, priced at $565 found 1 day ago
United
Wed, Jun 10 - Mon, Jun 29
RDU
Raleigh - Durham Intl.
PTY
Tocumen Intl.
$593 Roundtrip, found 1 day ago
$593
Roundtrip
found 1 day ago
Select United flight, departing Wed, Jun 10 from Raleigh - Durham Intl. to Tocumen Intl., returning Mon, Jun 29, priced at $593 found 1 day ago
Copa
Mon, Jul 27 - Wed, Jul 29
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$596 Roundtrip, found 1 hour ago
$596
Roundtrip
found 1 hour ago
Select Copa flight, departing Mon, Jul 27 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Wed, Jul 29, priced at $596 found 1 hour ago
American Airlines
Mon, Jun 22 - Mon, Jul 20
RDU
Raleigh - Durham Intl.
PTY
Tocumen Intl.
$596 Roundtrip, found 1 day ago
$596
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 22 from Raleigh - Durham Intl. to Tocumen Intl., returning Mon, Jul 20, priced at $596 found 1 day ago
Delta
Thu, Jul 9 - Wed, Jul 22
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$608 Roundtrip, found 4 days ago
$608
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jul 9 from Austin-Bergstrom Intl. to Tocumen Intl., returning Wed, Jul 22, priced at $608 found 4 days ago
Copa
Fri, Sep 18 - Wed, Sep 23
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$626 Roundtrip, found 1 hour ago
$626
Roundtrip
found 1 hour ago
Select Copa flight, departing Fri, Sep 18 from John F. Kennedy Intl. to Tocumen Intl., returning Wed, Sep 23, priced at $626 found 1 hour ago
United
Fri, Sep 18 - Wed, Sep 23
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$646 Roundtrip, found 1 hour ago
$646
Roundtrip
found 1 hour ago
Select United flight, departing Fri, Sep 18 from Newark Liberty Intl. Airport to Tocumen Intl., returning Wed, Sep 23, priced at $646 found 1 hour ago
Aeromexico
Mon, Aug 17 - Mon, Aug 31
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$1,021 Roundtrip, found 2 days ago
$1,021
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Mon, Aug 17 from Austin-Bergstrom Intl. to Tocumen Intl., returning Mon, Aug 31, priced at $1,021 found 2 days ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Panama Pacifico Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $250, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $250 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$249

Last Minute Hotel Deals in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,457 reviews)
"There is no weekend entertainment at this hotel,you only see the staff at the front desk. No one even call your room to ask how your experiences. Limited English language especially house keeping, room service. The staff at the front of the building are very helpful with transportation and understand ..."

Reviewed on May 21, 2026

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Hotel Riu Plaza Panama
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.2/10 Wonderful! (1,106 reviews)
"Staff at check in and in restaurant very nice and accommodating. Great gym with much more equipment than I have seen in most hotels. Very comfortable mattress on bed. You do hear some honking of cars from 2nd floor."

Reviewed on May 21, 2026

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The Executive Hotel
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,864 reviews)
"property was always clean the room was cleaned everyday no breakfast or snacks but there is a store right outside to get what you need. Also no microwave or anything like that so you will eat out for all your meals. Everything is near by to get something to eat"

Reviewed on May 20, 2026

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Principe Hotel and Suites
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.6/10 Good! (1,002 reviews)
"Not clean room I see lits of insects and cockroaches 😑"

Reviewed on May 20, 2026

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Dreams Playa Bonita Panama - All Inclusive
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Book a stay at this spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Avenida Balboa are ...
8.8/10 Excellent! (931 reviews)
"Breakfast was good, could be better."

Reviewed on May 20, 2026

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Waymore Hotel Spa & Casino
Hotel Ojos del Rio

Hotel Ojos del Rio

3.5 out of 5
calle 41 este Panama City Panama
Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (1,001 reviews)
"El hotel tiene que mejorar el la limpieza y tener unos mejores colchones para poder descansar tranquilos, en el buffet del desayuno no había mucha variedad en las comidas, casi todos los días era lo mismo y muchas cosas fritas, muy pocas cosas nutritivas. Sin embargo lo bueno es que queda cerca de ..."

Reviewed on May 20, 2026

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Hotel Ojos del Rio
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,002 reviews)
"Staff at front desk was most helpful and friendly. Kudos to Francisco. He was very welcoming and accommodating."

Reviewed on May 21, 2026

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Courtyard by Marriott Panama Multiplaza Mall
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street Panama City Panama
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,025 reviews)
"My stay at the Radisson Hotel Panama Canal was exceptional, thanks to both the property and its staff. Each morning began with the excellent daily breakfast at the Bridge View Restaurant, where the spread was fresh, varied, and always satisfying. Lunch at the Lobby Bar was a standout, so much so ..."

Reviewed on May 20, 2026

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Radisson Hotel Panama Canal
See all 1,738 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.