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Panama City

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Panama City Flights as Low as $169

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Wed, May 13 - Wed, May 20
ORD
O'Hare Intl.
PNS
Pensacola Intl.
$169 Roundtrip, found 20 hours ago
$169
Roundtrip
found 20 hours ago
Select Spirit Airlines flight, departing Wed, May 13 from O'Hare Intl. to Pensacola Intl., returning Wed, May 20, priced at $169 found 20 hours ago
American Airlines
Sat, May 2 - Thu, May 7
MSP
Minneapolis - St. Paul Intl.
VPS
Northwest Florida Regional
$188 Roundtrip, found 2 days ago
$188
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, May 2 from Minneapolis - St. Paul Intl. to Northwest Florida Regional, returning Thu, May 7, priced at $188 found 2 days ago
Spirit Airlines
Tue, Apr 21 - Wed, Apr 29
EWR
Newark Liberty Intl. Airport
PNS
Pensacola Intl.
$198 Roundtrip, found 2 hours ago
$198
Roundtrip
found 2 hours ago
Select Spirit Airlines flight, departing Tue, Apr 21 from Newark Liberty Intl. Airport to Pensacola Intl., returning Wed, Apr 29, priced at $198 found 2 hours ago
Sun Country Airlines
Sun, May 17 - Sat, May 23
MSP
Minneapolis - St. Paul Intl.
VPS
Northwest Florida Regional
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select Sun Country Airlines flight, departing Sun, May 17 from Minneapolis - St. Paul Intl. to Northwest Florida Regional, returning Sat, May 23, priced at $199 found 2 days ago
Frontier Airlines
Tue, May 5 - Thu, May 14
DTW
Detroit Metropolitan Wayne County
PNS
Pensacola Intl.
$203 Roundtrip, found 1 day ago
$203
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, May 5 from Detroit Metropolitan Wayne County to Pensacola Intl., returning Thu, May 14, priced at $203 found 1 day ago
Delta
Mon, May 4 - Tue, May 12
MSP
Minneapolis - St. Paul Intl.
VPS
Northwest Florida Regional
$221 Roundtrip, found 4 days ago
$221
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, May 4 from Minneapolis - St. Paul Intl. to Northwest Florida Regional, returning Tue, May 12, priced at $221 found 4 days ago
Bargain Flight
Sun, Sep 27 - Sat, Oct 3
MSP
Minneapolis - St. Paul Intl.
ECP
Northwest Florida Beaches Intl.
$267 Roundtrip, found 10 hours ago
$267
Roundtrip
found 10 hours ago
Select Bargain Flight flight, departing Sun, Sep 27 from Minneapolis - St. Paul Intl. to Northwest Florida Beaches Intl., returning Sat, Oct 3, priced at $267 found 10 hours ago
American Airlines
Tue, May 5 - Wed, May 13
ORD
O'Hare Intl.
ECP
Northwest Florida Beaches Intl.
$278 Roundtrip, found 3 hours ago
$278
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, May 5 from O'Hare Intl. to Northwest Florida Beaches Intl., returning Wed, May 13, priced at $278 found 3 hours ago
Delta
Wed, Jul 8 - Tue, Jul 14
EWR
Newark Liberty Intl. Airport
VPS
Northwest Florida Regional
$279 Roundtrip, found 17 hours ago
$279
Roundtrip
found 17 hours ago
Select Delta flight, departing Wed, Jul 8 from Newark Liberty Intl. Airport to Northwest Florida Regional, returning Tue, Jul 14, priced at $279 found 17 hours ago
Bargain Flight
Wed, Sep 9 - Wed, Sep 16
MSP
Minneapolis - St. Paul Intl.
PNS
Pensacola Intl.
$280 Roundtrip, found 5 days ago
$280
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Wed, Sep 9 from Minneapolis - St. Paul Intl. to Pensacola Intl., returning Wed, Sep 16, priced at $280 found 5 days ago
American Airlines
Wed, Jun 3 - Wed, Jun 17
EWR
Newark Liberty Intl. Airport
ECP
Northwest Florida Beaches Intl.
$288 Roundtrip, found 5 hours ago
$288
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, Jun 3 from Newark Liberty Intl. Airport to Northwest Florida Beaches Intl., returning Wed, Jun 17, priced at $288 found 5 hours ago
Frontier Airlines
Thu, Apr 16 - Mon, Apr 20
TTN
Mercer
PNS
Pensacola Intl.
$295 Roundtrip, found 1 day ago
$295
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Apr 16 from Mercer to Pensacola Intl., returning Mon, Apr 20, priced at $295 found 1 day ago
Delta
Tue, Jun 9 - Mon, Jun 15
DTW
Detroit Metropolitan Wayne County
VPS
Northwest Florida Regional
$325 Roundtrip, found 2 hours ago
$325
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Jun 9 from Detroit Metropolitan Wayne County to Northwest Florida Regional, returning Mon, Jun 15, priced at $325 found 2 hours ago
Delta
Tue, Jun 9 - Tue, Jun 16
DTW
Detroit Metropolitan Wayne County
ECP
Northwest Florida Beaches Intl.
$327 Roundtrip, found 1 hour ago
$327
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Jun 9 from Detroit Metropolitan Wayne County to Northwest Florida Beaches Intl., returning Tue, Jun 16, priced at $327 found 1 hour ago
American Airlines
Tue, May 19 - Thu, May 28
TTN
Mercer
ECP
Northwest Florida Beaches Intl.
$328 Roundtrip, found 22 hours ago
$328
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, May 19 from Mercer to Northwest Florida Beaches Intl., returning Thu, May 28, priced at $328 found 22 hours ago
American Airlines
Tue, Jun 2 - Tue, Jun 16
ORD
O'Hare Intl.
VPS
Northwest Florida Regional
$363 Roundtrip, found 20 hours ago
$363
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jun 2 from O'Hare Intl. to Northwest Florida Regional, returning Tue, Jun 16, priced at $363 found 20 hours ago

Cheap Flights to Panama City

Fall in love at first flight with your vacation to Panama City by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Panama City on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Panama City, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Panama City

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Panama City with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PNS airport.

What is the cheapest month to fly to Panama City?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Panama City are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Panama City?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Panama City.

What airport is best to fly into Panama City?

When you’re planning your trip to Panama City, convenience is the name of the game. Luckily, Panama City Northwest Florida Beaches Intl. Airport is nearby so you can deplane and get going on checking off everything on your Panama City must-do list.

How much are flights to Panama City?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Panama City on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $169, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Panama City?

The trick to saving a stack of cash on your flight to Panama City? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $169 right now, why wait?

Panama City Flight Information
Destination airport
Pensacola Intl.
Destination airport IATA code
PNS
Roundtrip price
$63

Last Minute Hotel Deals in Panama City

La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St Panama City FL
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,009 reviews)
Staff: 5 star Breakfast: 5 star Cleanliness: 5 star Overall 10 star 😊 Would book there again!!

Reviewed on Apr 13, 2026

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La Quinta Inn & Suites by Wyndham Panama City
Comfort Inn & Suites Panama City North

Comfort Inn & Suites Panama City North

2.5 out of 5
2317 Jenks Ave Panama City FL
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions St. Andrews State Park and ...
8.2/10 Very Good! (763 reviews)
The new manager is doing a fantastic job. Every room that we stay in was in great condition and very clean.

Reviewed on Apr 10, 2026

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Comfort Inn & Suites Panama City North
Hotel Indigo Panama City Marina by IHG

Hotel Indigo Panama City Marina by IHG

3.5 out of 5
7 HARRISON AVENUE Panama City FL
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a 24-hour fitness center. Our guests praise the helpful staff ...
9.6/10 Exceptional! (415 reviews)
Positive: Great roof top and food - great amenities Negative: Room a/c and ventilation system was very noisy. Didn't sleep well the first of a 3 night stay. Also, water noise from a pipe in the middle of the night. Asked again. Reception man said he didn't follow up. He would do again after we were ...

Reviewed on Apr 9, 2026

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Hotel Indigo Panama City Marina by IHG
Best Western Plus Panama City Hotel

Best Western Plus Panama City Hotel

2.5 out of 5
Mercedes Avenue, 2338 Panama City FL
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (925 reviews)
We could not have any of the breakfast because it didn’t start till seven and we needed to be out of there before seven. Try to get some coffee it was available however it was broken. The elevator was working fine at night but the next morning when we left with all of our stuff, we had to take stairs ...

Reviewed on Apr 13, 2026

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Best Western Plus Panama City Hotel
Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd Panama City FL
Book a stay at this business-friendly hotel in Panama City. Enjoy free parking, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (736 reviews)
The rooms were nice and clean very nice hotel you have to pay for breakfast and it’s made to order

Reviewed on Apr 12, 2026

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Hilton Garden Inn Panama City Airport
Holiday Inn Panama City by IHG

Holiday Inn Panama City by IHG

3 out of 5
2001 Martin Luther King Boulevard Panama City FL
Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (783 reviews)
Very nice stay!

Reviewed on Apr 10, 2026

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Holiday Inn Panama City by IHG
Courtyard by Marriott Panama City

Courtyard by Marriott Panama City

3 out of 5
905 E 23rd Pl Panama City FL
Book a stay at this business-friendly hotel in Panama City. Enjoy breakfast (surcharge), a 24-hour fitness center, and parking (surcharge). Popular attractions ...
9/10 Wonderful! (418 reviews)
Everything was great 😃

Reviewed on Apr 13, 2026

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Courtyard by Marriott Panama City
Red Roof Inn Panama City

Red Roof Inn Panama City

2 out of 5
217 North US Hwy 231 Panama City FL
Stay at this hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,004 reviews)
The best part of breakfast was the waffles, the breakfast eating area is very small. My room was clean for the most part other than seeing hairs in tandom places like in the shower on the shower curtain.

Reviewed on Apr 13, 2026

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Red Roof Inn Panama City
See all 15,537 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Palmetto Beachfront Hotel, a By the Sea Resort

Palmetto Beachfront Hotel, a By the Sea Resort

2 out of 5
17255 Front Beach Road Panama City Beach FL
Book a stay at this beach hotel in Panama City Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (2,356 reviews)
Ok stay

Reviewed on Apr 13, 2026

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Palmetto Beachfront Hotel, a By the Sea Resort
See all 15,537 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.