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O Brien

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O Brien Flights as Low as $76

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Jul 14 - Thu, Jul 16
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$76 Roundtrip, just found
$76
Roundtrip
just found
Select Frontier Airlines flight, departing Tue, Jul 14 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Thu, Jul 16, priced at $76 just found
Frontier Airlines
Tue, Jul 7 - Fri, Jul 10
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$78 Roundtrip, found 8 hours ago
$78
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Tue, Jul 7 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Fri, Jul 10, priced at $78 found 8 hours ago
Delta
Tue, Jul 14 - Thu, Jul 16
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$107 Roundtrip, just found
$107
Roundtrip
just found
Select Delta flight, departing Tue, Jul 14 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Thu, Jul 16, priced at $107 just found
Frontier Airlines
Tue, Jun 30 - Sun, Jul 12
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$107 Roundtrip, found 4 days ago
$107
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, Jun 30 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Sun, Jul 12, priced at $107 found 4 days ago
Frontier Airlines
Thu, Jul 9 - Sun, Jul 12
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$109 Roundtrip, found 2 days ago
$109
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Jul 9 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Sun, Jul 12, priced at $109 found 2 days ago
Delta
Thu, Nov 26 - Thu, Nov 26
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$114 Roundtrip, found 2 hours ago
$114
Roundtrip
found 2 hours ago
Select Delta flight, departing Thu, Nov 26 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Thu, Nov 26, priced at $114 found 2 hours ago
Frontier Airlines
Wed, Jul 29 - Wed, Aug 5
BWI
Baltimore Washington Intl. Thurgood Marshall
JAX
Jacksonville Intl.
$250 Roundtrip, found 2 hours ago
$250
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Baltimore Washington Intl. Thurgood Marshall to Jacksonville Intl., returning Wed, Aug 5, priced at $250 found 2 hours ago
Delta
Sat, Jul 4 - Sat, Jul 4
ATL
Hartsfield-Jackson Atlanta Intl.
TLH
Tallahassee Intl.
$294 Roundtrip, found 23 hours ago
$294
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Jul 4 from Hartsfield-Jackson Atlanta Intl. to Tallahassee Intl., returning Sat, Jul 4, priced at $294 found 23 hours ago
American Airlines
Wed, Jul 29 - Wed, Aug 5
BWI
Baltimore Washington Intl. Thurgood Marshall
JAX
Jacksonville Intl.
$296 Roundtrip, found 2 hours ago
$296
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Jul 29 from Baltimore Washington Intl. Thurgood Marshall to Jacksonville Intl., returning Wed, Aug 5, priced at $296 found 2 hours ago
JetBlue Airways
Wed, Aug 19 - Tue, Aug 25
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$363 Roundtrip, found 5 hours ago
$363
Roundtrip
found 5 hours ago
Select JetBlue Airways flight, departing Wed, Aug 19 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Tue, Aug 25, priced at $363 found 5 hours ago
Delta
Tue, Sep 22 - Sat, Sep 26
BWI
Baltimore Washington Intl. Thurgood Marshall
TLH
Tallahassee Intl.
$377 Roundtrip, found 2 days ago
$377
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Sep 22 from Baltimore Washington Intl. Thurgood Marshall to Tallahassee Intl., returning Sat, Sep 26, priced at $377 found 2 days ago
Frontier Airlines
Thu, Jun 18 - Tue, Jun 23
MIA
Miami Intl.
JAX
Jacksonville Intl.
$400 Roundtrip, found 1 day ago
$400
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Jun 18 from Miami Intl. to Jacksonville Intl., returning Tue, Jun 23, priced at $400 found 1 day ago
Delta
Wed, Jun 17 - Mon, Jun 29
BWI
Baltimore Washington Intl. Thurgood Marshall
GNV
Gainesville Regional
$471 Roundtrip, found 5 days ago
$471
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jun 17 from Baltimore Washington Intl. Thurgood Marshall to Gainesville Regional, returning Mon, Jun 29, priced at $471 found 5 days ago
Delta
Tue, Jun 16 - Sat, Jun 20
MIA
Miami Intl.
TLH
Tallahassee Intl.
$480 Roundtrip, found 1 day ago
$480
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 16 from Miami Intl. to Tallahassee Intl., returning Sat, Jun 20, priced at $480 found 1 day ago
Accessrail
Thu, Jun 18 - Thu, Jun 25
EKW
Miami Central Brightline Train Station
JAX
Jacksonville Intl.
$491 Roundtrip, found 1 day ago
$491
Roundtrip
found 1 day ago
Select Accessrail flight, departing Thu, Jun 18 from Miami Central Brightline Train Station to Jacksonville Intl., returning Thu, Jun 25, priced at $491 found 1 day ago
United
Wed, Jul 29 - Wed, Aug 5
BWI
Baltimore Washington Intl. Thurgood Marshall
JAX
Jacksonville Intl.
$522 Roundtrip, found 2 hours ago
$522
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Jul 29 from Baltimore Washington Intl. Thurgood Marshall to Jacksonville Intl., returning Wed, Aug 5, priced at $522 found 2 hours ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $76, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $76 right now, why wait?

O Brien Flight Information
Destination airport
Jacksonville Intl.
Destination airport IATA code
JAX
Roundtrip price
$197

Last Minute Hotel Deals in O Brien

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,126 reviews)
"Stayed for the night while traveling. Enjoyed the comfortable, clean room. The staff was courteous."

Reviewed on Jun 14, 2026

Get rates
La Quinta Inn & Suite by Wyndham Lake City
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD Alachua FL
Book a stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,019 reviews)
"Was what it should be. Easy, clean and convenient."

Reviewed on Jun 14, 2026

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Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
10/10 Exceptional! (223 reviews)
"Amazing spot to be out of the world."

Reviewed on Jun 3, 2026

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Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 out of 5
284 NW Centurion Court Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,019 reviews)
"Newer property with good amenities. No issues."

Reviewed on Jun 14, 2026

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Tru by Hilton Lake City
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,021 reviews)
"Everything was clean from our room to the fitness center. Breakfast was good too!"

Reviewed on Jun 13, 2026

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Comfort Suites Lake City
Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75

2.5 out of 5
3598 W Us Highway 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
5/10 (1,005 reviews)
"Some of the Bed linen was stained,room was clean bathroom as well."

Reviewed on Jun 14, 2026

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Baymont by Wyndham Lake City I-75
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,075 reviews)
"The room was clean. Parking and location convenient. Breakfast was very good and changed both mornings we enjoyed it. Only negative was they only had one luggage cart to transport our things. Someone was using it when we came and we had to carry our things. We enjoyed our stay and trip to Ichtucknee ..."

Reviewed on Jun 14, 2026

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Best Western Plus Lake City
Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10

2 out of 5
3430 N Us Highway 441 Lake City FL
Book a stay at this business-friendly motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,008 reviews)
"Nice and restful place to stay"

Reviewed on Jun 8, 2026

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Days Inn by Wyndham Lake City I-10
See all 374 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.