Search Cheap Flights to
O Brien

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O Brien Flights as Low as $120

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, Aug 11 - Mon, Aug 18
DFW
Dallas-Fort Worth Intl.
JAX
Jacksonville Intl.
$120 Roundtrip, found 23 hours ago
$120
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Mon, Aug 11 from Dallas-Fort Worth Intl. to Jacksonville Intl., returning Mon, Aug 18, priced at $120 found 23 hours ago
Frontier Airlines
Mon, Aug 11 - Mon, Aug 18
DFW
Dallas-Fort Worth Intl.
JAX
Jacksonville Intl.
$141 Roundtrip, found 23 hours ago
$141
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Mon, Aug 11 from Dallas-Fort Worth Intl. to Jacksonville Intl., returning Mon, Aug 18, priced at $141 found 23 hours ago
American Airlines
Tue, Nov 4 - Sat, Nov 8
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$159 Roundtrip, found 8 hours ago
$159
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Nov 4 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sat, Nov 8, priced at $159 found 8 hours ago
Delta
Tue, Nov 4 - Sat, Nov 8
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$159 Roundtrip, found 8 hours ago
$159
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Nov 4 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sat, Nov 8, priced at $159 found 8 hours ago
United
Wed, Oct 22 - Mon, Oct 27
DFW
Dallas-Fort Worth Intl.
JAX
Jacksonville Intl.
$197 Roundtrip, found 6 days ago
$197
Roundtrip
found 6 days ago
Select United flight, departing Wed, Oct 22 from Dallas-Fort Worth Intl. to Jacksonville Intl., returning Mon, Oct 27, priced at $197 found 6 days ago
Delta
Mon, Aug 11 - Mon, Aug 18
DAL
Love Field
JAX
Jacksonville Intl.
$200 Roundtrip, found 23 hours ago
$200
Roundtrip
found 23 hours ago
Select Delta flight, departing Mon, Aug 11 from Love Field to Jacksonville Intl., returning Mon, Aug 18, priced at $200 found 23 hours ago
Bargain Flight
Thu, Dec 11 - Tue, Dec 16
CLE
Hopkins Intl.
JAX
Jacksonville Intl.
$231 Roundtrip, found 1 day ago
$231
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Dec 11 from Hopkins Intl. to Jacksonville Intl., returning Tue, Dec 16, priced at $231 found 1 day ago
JetBlue Airways
Wed, Oct 15 - Fri, Oct 24
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$241 Roundtrip, found 2 days ago
$241
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Wed, Oct 15 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Fri, Oct 24, priced at $241 found 2 days ago
American Airlines
Tue, Sep 16 - Tue, Sep 23
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$251 Roundtrip, found 12 hours ago
$251
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Tue, Sep 16 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 23, priced at $251 found 12 hours ago
American Airlines
Tue, Nov 11 - Sat, Nov 15
CLE
Hopkins Intl.
TLH
Tallahassee Intl.
$271 Roundtrip, found 9 hours ago
$271
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Nov 11 from Hopkins Intl. to Tallahassee Intl., returning Sat, Nov 15, priced at $271 found 9 hours ago
Delta
Sat, Aug 30 - Tue, Sep 2
DAL
Love Field
TLH
Tallahassee Intl.
$319 Roundtrip, found 10 hours ago
$319
Roundtrip
found 10 hours ago
Select Delta flight, departing Sat, Aug 30 from Love Field to Tallahassee Intl., returning Tue, Sep 2, priced at $319 found 10 hours ago
Delta
Tue, Sep 23 - Tue, Sep 30
DAL
Love Field
GNV
Gainesville Regional
$319 Roundtrip, found 9 hours ago
$319
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Sep 23 from Love Field to Gainesville Regional, returning Tue, Sep 30, priced at $319 found 9 hours ago
Delta
Tue, Sep 23 - Tue, Sep 30
DFW
Dallas-Fort Worth Intl.
GNV
Gainesville Regional
$319 Roundtrip, found 9 hours ago
$319
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Sep 23 from Dallas-Fort Worth Intl. to Gainesville Regional, returning Tue, Sep 30, priced at $319 found 9 hours ago
Delta
Thu, Aug 28 - Sun, Aug 31
DFW
Dallas-Fort Worth Intl.
TLH
Tallahassee Intl.
$354 Roundtrip, found 11 hours ago
$354
Roundtrip
found 11 hours ago
Select Delta flight, departing Thu, Aug 28 from Dallas-Fort Worth Intl. to Tallahassee Intl., returning Sun, Aug 31, priced at $354 found 11 hours ago
American Airlines
Wed, Jul 9 - Tue, Jul 15
CLE
Hopkins Intl.
GNV
Gainesville Regional
$375 Roundtrip, found 2 days ago
$375
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Jul 9 from Hopkins Intl. to Gainesville Regional, returning Tue, Jul 15, priced at $375 found 2 days ago
Delta
Fri, Jul 11 - Thu, Jul 17
DAL
Love Field
VLD
Valdosta Regional
$536 Roundtrip, found 6 days ago
$536
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Jul 11 from Love Field to Valdosta Regional, returning Thu, Jul 17, priced at $536 found 6 days ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $120, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $120 right now, why wait?

O Brien Flight Information
Destination airport
Jacksonville Intl.
Destination airport IATA code
JAX
Roundtrip price
$120

Last Minute Hotel Deals in O Brien

La Quinta Inn & Suite by Wyndham Lake City
La Quinta Inn & Suite by Wyndham Lake City
2.5 out of 5
165NW CALI DRIVE, Lake City, FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,007 reviews)
"Location clean and a lot of restaurants near ,"

Reviewed on Jul 6, 2025

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La Quinta Inn & Suite by Wyndham Lake City
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 out of 5
16367 NW 167TH BLVD, Alachua, FL
Stay at this 3.5-star business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,008 reviews)
Perfect one nighter
"Perfect for our one night stay as we’re driving back from a long week vacation."

Reviewed on Jul 7, 2025

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Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Best Western Plus Lake City
Best Western Plus Lake City
2.5 out of 5
350 SW Florida Gateway Dr, Lake City, FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,002 reviews)
"Very clean and well-kept"

Reviewed on Jul 6, 2025

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Best Western Plus Lake City
Postcard Cabins Gilchrist Springs
Postcard Cabins Gilchrist Springs
2 out of 5
1699 NE Co Rd 337, High Springs, FL
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
10/10 Exceptional! (41 reviews)
"Wonderful, romantic getaway! Very clean and accommodating. Grocery store is 15 min in town (high springs) close to several springs and parks! Property is nice and quiet! We had a wasp infestation at our door entry and the response time was fantastic! Sprayed the area and let us keep a can just in ..."

Reviewed on Jun 29, 2025

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Postcard Cabins Gilchrist Springs
Comfort Suites Lake City
Comfort Suites Lake City
2.5 out of 5
3690 W Us Highway 90, Lake City, FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,006 reviews)
"We have stayed at this property many times over the last few years and have always been very happy with the facility and value!"

Reviewed on Jul 4, 2025

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Comfort Suites Lake City
Tru by Hilton Lake City
Tru by Hilton Lake City
2.5 out of 5
284 NW Centurion Court, Lake City, FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"Very nice"

Reviewed on Jun 30, 2025

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Tru by Hilton Lake City
Baymont by Wyndham Lake City
Baymont by Wyndham Lake City
2.5 out of 5
3598 W Us Highway 90, Lake City, FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
5/10 (1,004 reviews)
Good experience
"Stayed here a few times now and always been had a good experience. The staff was always friendly and on top of things."

Reviewed on Jul 3, 2025

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Baymont by Wyndham Lake City
Courtyard By Marriott Lake City
Courtyard By Marriott Lake City
3 out of 5
3004 West US HWY 90, Lake City, FL
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Regal UA Cinema 90 and ...
9.6/10 Exceptional! (105 reviews)
"Everything was good. Bed was big & comfy. Room was clean. We ended up booking a second night in a different room for a reason not related to the hotel. TP was your standard, thin TP. And the shower leaked, bad. I turned on the water and while i was getting ready to get in, water was pooling outside ..."

Reviewed on Jul 2, 2025

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Courtyard By Marriott Lake City
See all 328 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.