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O Brien

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O Brien Flights as Low as $151

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, Apr 27 - Thu, May 14
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$151 Roundtrip, found 10 hours ago
$151
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Mon, Apr 27 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Thu, May 14, priced at $151 found 10 hours ago
Frontier Airlines
Mon, Mar 23 - Wed, Apr 1
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$163 Roundtrip, found 3 days ago
$163
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Mar 23 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Wed, Apr 1, priced at $163 found 3 days ago
Frontier Airlines
Mon, Apr 27 - Sat, May 9
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$166 Roundtrip, found 2 days ago
$166
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Apr 27 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Sat, May 9, priced at $166 found 2 days ago
Frontier Airlines
Sun, Apr 12 - Mon, Apr 20
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$169 Roundtrip, found 2 days ago
$169
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Apr 12 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Mon, Apr 20, priced at $169 found 2 days ago
Frontier Airlines
Mon, Apr 6 - Thu, Apr 30
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$173 Roundtrip, found 2 days ago
$173
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Apr 6 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Thu, Apr 30, priced at $173 found 2 days ago
Frontier Airlines
Thu, Apr 9 - Fri, Apr 17
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$175 Roundtrip, found 4 days ago
$175
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Apr 9 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Fri, Apr 17, priced at $175 found 4 days ago
Frontier Airlines
Mon, May 4 - Sat, May 16
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$177 Roundtrip, found 1 day ago
$177
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, May 4 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Sat, May 16, priced at $177 found 1 day ago
Frontier Airlines
Mon, Apr 27 - Fri, May 8
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$178 Roundtrip, found 1 day ago
$178
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Apr 27 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Fri, May 8, priced at $178 found 1 day ago
Delta
Mon, May 11 - Tue, May 19
BOS
Logan Intl.
JAX
Jacksonville Intl.
$187 Roundtrip, found 6 hours ago
$187
Roundtrip
found 6 hours ago
Select Delta flight, departing Mon, May 11 from Logan Intl. to Jacksonville Intl., returning Tue, May 19, priced at $187 found 6 hours ago
JetBlue Airways
Sat, May 2 - Sat, May 9
BOS
Logan Intl.
JAX
Jacksonville Intl.
$194 Roundtrip, found 2 hours ago
$194
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Sat, May 2 from Logan Intl. to Jacksonville Intl., returning Sat, May 9, priced at $194 found 2 hours ago
United
Mon, May 11 - Sat, May 16
BOS
Logan Intl.
JAX
Jacksonville Intl.
$207 Roundtrip, found 7 hours ago
$207
Roundtrip
found 7 hours ago
Select United flight, departing Mon, May 11 from Logan Intl. to Jacksonville Intl., returning Sat, May 16, priced at $207 found 7 hours ago
American Airlines
Wed, May 13 - Wed, May 20
BOS
Logan Intl.
JAX
Jacksonville Intl.
$208 Roundtrip, found 6 hours ago
$208
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, May 13 from Logan Intl. to Jacksonville Intl., returning Wed, May 20, priced at $208 found 6 hours ago
Delta
Wed, May 20 - Wed, Jun 10
ATL
Hartsfield-Jackson Atlanta Intl.
TLH
Tallahassee Intl.
$219 Roundtrip, found 11 hours ago
$219
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, May 20 from Hartsfield-Jackson Atlanta Intl. to Tallahassee Intl., returning Wed, Jun 10, priced at $219 found 11 hours ago
Delta
Thu, Apr 9 - Wed, Apr 15
ATL
Hartsfield-Jackson Atlanta Intl.
VLD
Valdosta Regional
$225 Roundtrip, found 2 days ago
$225
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Apr 9 from Hartsfield-Jackson Atlanta Intl. to Valdosta Regional, returning Wed, Apr 15, priced at $225 found 2 days ago
American Airlines
Wed, Mar 25 - Tue, Mar 31
BOS
Logan Intl.
GNV
Gainesville Regional
$334 Roundtrip, found 1 day ago
$334
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Mar 25 from Logan Intl. to Gainesville Regional, returning Tue, Mar 31, priced at $334 found 1 day ago
United
Tue, May 12 - Mon, Jun 8
GUA
La Aurora Intl.
JAX
Jacksonville Intl.
$457 Roundtrip, found 11 hours ago
$457
Roundtrip
found 11 hours ago
Select United flight, departing Tue, May 12 from La Aurora Intl. to Jacksonville Intl., returning Mon, Jun 8, priced at $457 found 11 hours ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $151, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $151 right now, why wait?

O Brien Flight Information
Destination airport
Jacksonville Intl.
Destination airport IATA code
JAX
Roundtrip price
$150

Last Minute Hotel Deals in O Brien

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,087 reviews)
We were traveling with our dog who was welcomed with a goodie bag! As I searched for accommodations I found that the pet fee here was quite a bit less than other hotels. There was also a very nice area for walks. The room was very nice and comfortable and the breakfast was great!

Reviewed on Mar 10, 2026

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La Quinta Inn & Suite by Wyndham Lake City
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,038 reviews)
The hotel was clean, but attention to details needs improvement. For example, the body wash bottle was empty in the shower, the tissue box was nearly empty, the charging station for phone wasn’t working, and the toaster at breakfast was broken. These are little things, but easy to fix so future ...

Reviewed on Mar 10, 2026

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Best Western Plus Lake City
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
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Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

2.5 out of 5
6694 Us Highway 129 Live Oak FL
Book a stay at this business-friendly hotel in Live Oak. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (806 reviews)
Served its purpose, what you see is what you get. Property is clean and staff is accommodating

Reviewed on Mar 9, 2026

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Holiday Inn Express & Suites Live Oak by IHG
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2 out of 5
3835 West US Highway 90 Lake City FL
Stay at this motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (1,002 reviews)
Clean room, hot shower. Beds were meh, property slightly rundown, but for the $$ 3.5 stars

Reviewed on Mar 10, 2026

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Americas Best Value Inn Lake City
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 out of 5
284 NW Centurion Court Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,004 reviews)
Room was clean. And staff was courteous

Reviewed on Mar 1, 2026

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Tru by Hilton Lake City
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,001 reviews)
aC really noisey. Beds excellent

Reviewed on Mar 11, 2026

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Comfort Suites Lake City
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

3 out of 5
213 Sw Commerce Dr Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (1,000 reviews)
Quick service and clean rooms

Reviewed on Mar 10, 2026

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Holiday Inn & Suites Lake City by IHG
See all 368 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.