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Myrtle

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Myrtle Flights as Low as $467

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$467 Roundtrip, found 14 hours ago
$467
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $467 found 14 hours ago
United
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$472 Roundtrip, found 14 hours ago
$472
Roundtrip
found 14 hours ago
Select United flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $472 found 14 hours ago
American Airlines
Tue, Mar 31 - Sat, Apr 18
ORF
Norfolk Intl.
TUP
Tupelo Regional
$486 Roundtrip, found 22 hours ago
$486
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Mar 31 from Norfolk Intl. to Tupelo Regional, returning Sat, Apr 18, priced at $486 found 22 hours ago
American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$487 Roundtrip, found 1 day ago
$487
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $487 found 1 day ago
American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$491 Roundtrip, found 14 hours ago
$491
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $491 found 14 hours ago
American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$493 Roundtrip, found 14 hours ago
$493
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $493 found 14 hours ago
American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$501 Roundtrip, found 12 hours ago
$501
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $501 found 12 hours ago
American Airlines
Tue, Mar 31 - Sat, Apr 18
ORF
Norfolk Intl.
TUP
Tupelo Regional
$506 Roundtrip, found 22 hours ago
$506
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Mar 31 from Norfolk Intl. to Tupelo Regional, returning Sat, Apr 18, priced at $506 found 22 hours ago
American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$511 Roundtrip, found 1 day ago
$511
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $511 found 1 day ago
American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$513 Roundtrip, found 14 hours ago
$513
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $513 found 14 hours ago
American Airlines
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$513 Roundtrip, found 1 day ago
$513
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $513 found 1 day ago
United
Sat, Apr 11 - Tue, Apr 14
BWI
Baltimore Washington Intl. Thurgood Marshall
TUP
Tupelo Regional
$515 Roundtrip, just found
$515
Roundtrip
just found
Select United flight, departing Sat, Apr 11 from Baltimore Washington Intl. Thurgood Marshall to Tupelo Regional, returning Tue, Apr 14, priced at $515 just found
United
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$517 Roundtrip, found 14 hours ago
$517
Roundtrip
found 14 hours ago
Select United flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $517 found 14 hours ago
United
Mon, Apr 27 - Tue, May 5
SEA
Seattle - Tacoma Intl.
TUP
Tupelo Regional
$518 Roundtrip, found 14 hours ago
$518
Roundtrip
found 14 hours ago
Select United flight, departing Mon, Apr 27 from Seattle - Tacoma Intl. to Tupelo Regional, returning Tue, May 5, priced at $518 found 14 hours ago
American Airlines
Tue, Mar 31 - Sat, Apr 18
ORF
Norfolk Intl.
TUP
Tupelo Regional
$519 Roundtrip, found 22 hours ago
$519
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Mar 31 from Norfolk Intl. to Tupelo Regional, returning Sat, Apr 18, priced at $519 found 22 hours ago
United
Sun, May 24 - Fri, May 29
XWA
Basin Intl.
TUP
Tupelo Regional
$1,040 Roundtrip, found 1 day ago
$1,040
Roundtrip
found 1 day ago
Select United flight, departing Sun, May 24 from Basin Intl. to Tupelo Regional, returning Fri, May 29, priced at $1,040 found 1 day ago

Cheap Flights to Myrtle

Fall in love at first flight with your vacation to Myrtle by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Myrtle on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Myrtle, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Myrtle

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Myrtle with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TUP airport.

What is the cheapest month to fly to Myrtle?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Myrtle are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Myrtle?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Myrtle.

What airport is best to fly into Myrtle?

When you’re planning your trip to Myrtle, convenience is the name of the game. Luckily, Myrtle University - Oxford Airport is nearby so you can deplane and get going on checking off everything on your Myrtle must-do list.

How much are flights to Myrtle?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Myrtle on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $467, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Myrtle?

The trick to saving a stack of cash on your flight to Myrtle? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $467 right now, why wait?

Myrtle Flight Information
Destination airport
Tupelo Regional
Destination airport IATA code
TUP
Roundtrip price
$467

Last Minute Hotel Deals in Myrtle

The Inn at Ole Miss

The Inn at Ole Miss

3 out of 5
120 Alumni Drive University MS
Book a stay at this business-friendly hotel in University. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,003 reviews)
The location is great but I dont think our bathroom had been cleaned in awhile... like hair in the shower, on the floor and the back of the toilet to include noticable dried up urine when you close the toilet lid. I did veeify it was hair or dried up urine in both places with tissue and it was... ...

Reviewed on Mar 23, 2026

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The Inn at Ole Miss
La Quinta Inn & Suites by Wyndham Oxford

La Quinta Inn & Suites by Wyndham Oxford

3 out of 5
1171 Frontage Road Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (978 reviews)
I will definitely be back! This hotel was great! Kind staff, clean rooms and common areas! Loved it!

Reviewed on Mar 23, 2026

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La Quinta Inn & Suites by Wyndham Oxford
Tru by Hilton Oxford

Tru by Hilton Oxford

2.5 out of 5
97 Ed Perry Blvd Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (933 reviews)
The bedding and the mattress could of been better quality.

Reviewed on Mar 25, 2026

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Tru by Hilton Oxford
Graduate by Hilton Oxford

Graduate by Hilton Oxford

4 out of 5
400 North Lamar Boulevard Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
I love this chain and have stayed at a number of Graduate Hotels. This one felt a little empty. I didn’t feel the character of the others - maybe it’s the large lobby, maybe it’s the decor of rooms. It just felt like it was a “thinner” version of the other fab Graduate Hotels (Ann Arbor, New ...

Reviewed on Mar 24, 2026

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Graduate by Hilton Oxford
The Oliver Hotel, Oxford

The Oliver Hotel, Oxford

4 out of 5
425 S Lamar Blvd Oxford MS
Stay at this hotel in Oxford. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (344 reviews)
The place is beautiful and in the perfect location. The beds are insanely comfortable, and the linens soft. Absolutely adored this place.

Reviewed on Mar 27, 2026

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The Oliver Hotel, Oxford
Best Western New Albany

Best Western New Albany

2.5 out of 5
400 State Highway 30 W New Albany MS
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
Very nice place to stay clean convenient to the highway and a great breakfast and very friendly people. Stayed the night of three 2526.

Reviewed on Mar 26, 2026

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Best Western New Albany
Hampton Inn New Albany

Hampton Inn New Albany

2.5 out of 5
320 Coulter Cv New Albany MS
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (755 reviews)
Breakfast was good.

Reviewed on Mar 26, 2026

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Hampton Inn New Albany
Courtyard by Marriott Oxford

Courtyard by Marriott Oxford

3 out of 5
305 Jackson Avenue East Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (539 reviews)
The room was $700 a night we stayed for 2 nights and it was never cleaned or restocked. We had to go to the front desk for toilet paper and towels. They gave us one roll of toilet paper for 3 guests and never restocked. Good location but not worth it for the price.

Reviewed on Mar 27, 2026

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Courtyard by Marriott Oxford
See all 596 properties in Myrtle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.