Search Cheap Flights to
Myrtle

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Myrtle Flights as Low as $640

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
American Airlines
American Airlines
United
American Airlines
United
American Airlines
United
United
United
United
American Airlines
American Airlines
United
United
United

Cheap Flights to Myrtle

Fall in love at first flight with your vacation to Myrtle by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Myrtle on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Myrtle, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Myrtle

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Myrtle with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TUP airport.

What is the cheapest month to fly to Myrtle?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Myrtle are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Myrtle?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Myrtle.

What airport is best to fly into Myrtle?

When you’re planning your trip to Myrtle, convenience is the name of the game. Luckily, Myrtle University - Oxford Airport is nearby so you can deplane and get going on checking off everything on your Myrtle must-do list.

How much are flights to Myrtle?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Myrtle on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $640, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Myrtle?

The trick to saving a stack of cash on your flight to Myrtle? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $640 right now, why wait?

Myrtle Flight Information
Destination airport
Tupelo Regional
Destination airport IATA code
TUP
Roundtrip price
$639

Last Minute Hotel Deals in Myrtle

La Quinta Inn & Suites by Wyndham Oxford

La Quinta Inn & Suites by Wyndham Oxford

3 out of 5
1171 Frontage Road Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (938 reviews)
Convenient location. Clean room. Comfortable. Quiet. Great service

Reviewed on Jan 17, 2026

La Quinta Inn & Suites by Wyndham Oxford
Graduate by Hilton Oxford

Graduate by Hilton Oxford

4 out of 5
400 North Lamar Boulevard Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
Great Location, Lovely staff, Exquisite Decor & Comfy Room! Extra comfy Mattresses! This is the best place to stay in Oxford!!!!

Reviewed on Jan 13, 2026

Graduate by Hilton Oxford
Tru by Hilton Oxford

Tru by Hilton Oxford

2.5 out of 5
97 Ed Perry Blvd Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (891 reviews)
Ery nice

Reviewed on Jan 15, 2026

Tru by Hilton Oxford
The Inn at Ole Miss

The Inn at Ole Miss

3 out of 5
120 Alumni Drive University MS
Book a stay at this business-friendly hotel in University. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Always the very best!

Reviewed on Jan 20, 2026

The Inn at Ole Miss
Best Western New Albany

Best Western New Albany

2.5 out of 5
400 State Highway 30 W New Albany MS
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
Clean room

Reviewed on Jan 4, 2026

Best Western New Albany
 The Oliver Hotel, Oxford

The Oliver Hotel, Oxford

4 out of 5
425 S Lamar Blvd Oxford MS
Stay at this hotel in Oxford. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (328 reviews)
Wonderful!

Reviewed on Dec 20, 2025

The Oliver Hotel, Oxford
Hampton Inn Oxford/Conference Center

Hampton Inn Oxford/Conference Center

2.5 out of 5
103 Ed Perry Blvd Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (497 reviews)
Room was clean. Front desk staff was very friendly.

Reviewed on Jan 20, 2026

Hampton Inn Oxford/Conference Center
Courtyard by Marriott Oxford

Courtyard by Marriott Oxford

3 out of 5
305 Jackson Avenue East Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (535 reviews)
Courtest

Reviewed on Jan 13, 2026

Courtyard by Marriott Oxford
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.