Search Cheap Flights to
Muscatine

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Muscatine Flights as Low as $198

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Fri, Jul 4 - Tue, Jul 15
AUS
Austin-Bergstrom Intl.
MLI
Quad City Intl.
$198 Roundtrip, found 1 day ago
$198
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jul 4 from Austin-Bergstrom Intl. to Quad City Intl., returning Tue, Jul 15, priced at $198 found 1 day ago
Bargain Flight
Tue, Sep 30 - Tue, Oct 7
PNS
Pensacola Intl.
MLI
Quad City Intl.
$231 Roundtrip, found 5 days ago
$231
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Tue, Sep 30 from Pensacola Intl. to Quad City Intl., returning Tue, Oct 7, priced at $231 found 5 days ago
American Airlines
Fri, Jul 4 - Tue, Jul 15
AUS
Austin-Bergstrom Intl.
MLI
Quad City Intl.
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jul 4 from Austin-Bergstrom Intl. to Quad City Intl., returning Tue, Jul 15, priced at $234 found 1 day ago
American Airlines
Wed, Sep 17 - Tue, Sep 23
MCO
Orlando Intl.
MLI
Quad City Intl.
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 17 from Orlando Intl. to Quad City Intl., returning Tue, Sep 23, priced at $239 found 1 day ago
American Airlines
Wed, Sep 17 - Tue, Sep 23
MCO
Orlando Intl.
MLI
Quad City Intl.
$245 Roundtrip, found 1 day ago
$245
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 17 from Orlando Intl. to Quad City Intl., returning Tue, Sep 23, priced at $245 found 1 day ago
Delta
Fri, Jul 4 - Tue, Jul 15
AUS
Austin-Bergstrom Intl.
MLI
Quad City Intl.
$247 Roundtrip, found 1 day ago
$247
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Jul 4 from Austin-Bergstrom Intl. to Quad City Intl., returning Tue, Jul 15, priced at $247 found 1 day ago
American Airlines
Tue, Sep 30 - Tue, Oct 7
PNS
Pensacola Intl.
MLI
Quad City Intl.
$249 Roundtrip, found 5 days ago
$249
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 30 from Pensacola Intl. to Quad City Intl., returning Tue, Oct 7, priced at $249 found 5 days ago
Delta
Tue, Sep 16 - Tue, Sep 23
MCO
Orlando Intl.
MLI
Quad City Intl.
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 16 from Orlando Intl. to Quad City Intl., returning Tue, Sep 23, priced at $251 found 1 day ago
Delta
Sat, Jul 5 - Fri, Jul 18
AUS
Austin-Bergstrom Intl.
MLI
Quad City Intl.
$253 Roundtrip, found 3 days ago
$253
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Jul 5 from Austin-Bergstrom Intl. to Quad City Intl., returning Fri, Jul 18, priced at $253 found 3 days ago
American Airlines
Tue, Jul 22 - Sat, Jul 26
CLT
Charlotte-Douglas Intl.
MLI
Quad City Intl.
$301 Roundtrip, found 3 days ago
$301
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jul 22 from Charlotte-Douglas Intl. to Quad City Intl., returning Sat, Jul 26, priced at $301 found 3 days ago
Delta
Wed, Aug 13 - Sun, Aug 24
SJU
Luis Munoz Marin Intl.
MLI
Quad City Intl.
$305 Roundtrip, found 1 day ago
$305
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Aug 13 from Luis Munoz Marin Intl. to Quad City Intl., returning Sun, Aug 24, priced at $305 found 1 day ago
Delta
Tue, Jun 17 - Tue, Jun 24
BDL
Bradley Intl.
MLI
Quad City Intl.
$332 Roundtrip, found 4 days ago
$332
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Jun 17 from Bradley Intl. to Quad City Intl., returning Tue, Jun 24, priced at $332 found 4 days ago
United
Mon, Jun 30 - Wed, Jul 2
PDX
Portland Intl.
MLI
Quad City Intl.
$383 Roundtrip, found 4 days ago
$383
Roundtrip
found 4 days ago
Select United flight, departing Mon, Jun 30 from Portland Intl. to Quad City Intl., returning Wed, Jul 2, priced at $383 found 4 days ago
American Airlines
Wed, Jul 30 - Tue, Aug 5
ABE
Lehigh Valley Intl.
MLI
Quad City Intl.
$427 Roundtrip, found 4 days ago
$427
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Jul 30 from Lehigh Valley Intl. to Quad City Intl., returning Tue, Aug 5, priced at $427 found 4 days ago
United
Mon, Jun 16 - Tue, Jun 17
RDU
Raleigh - Durham Intl.
MLI
Quad City Intl.
$551 Roundtrip, found 3 days ago
$551
Roundtrip
found 3 days ago
Select United flight, departing Mon, Jun 16 from Raleigh - Durham Intl. to Quad City Intl., returning Tue, Jun 17, priced at $551 found 3 days ago
Alaska Airlines
Sun, Jun 29 - Sat, Jul 5
PDX
Portland Intl.
MLI
Quad City Intl.
$724 Roundtrip, found 4 days ago
$724
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Sun, Jun 29 from Portland Intl. to Quad City Intl., returning Sat, Jul 5, priced at $724 found 4 days ago

Cheap Flights to Muscatine

Fall in love at first flight with your vacation to Muscatine by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Muscatine on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Muscatine, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Muscatine

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Muscatine with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MLI airport.

What is the cheapest month to fly to Muscatine?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Muscatine are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Muscatine?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Muscatine.

What airport is best to fly into Muscatine?

When you’re planning your trip to Muscatine, convenience is the name of the game. Luckily, Muscatine Quad City Intl. Airport is nearby so you can deplane and get going on checking off everything on your Muscatine must-do list.

How much are flights to Muscatine?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Muscatine on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $198, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Muscatine?

The trick to saving a stack of cash on your flight to Muscatine? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $198 right now, why wait?

Muscatine Flight Information
Destination airport
Quad City Intl.
Destination airport IATA code
MLI
Roundtrip price
$198

Last Minute Hotel Deals in Muscatine

Best Western Muscatine / Pearl City Hotel
Best Western Muscatine / Pearl City Hotel
2.5 out of 5
305 Cleveland St, Muscatine, IA
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (448 reviews)
"Staff was prompt and courteous - they paid good attention to the breakfast area and kept things stocked. Hotel was clean and well kept. Pool area was rather small and very full with lots of kids. Overall, good stay!"

Reviewed on May 19, 2025

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Best Western Muscatine / Pearl City Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4 out of 5
119 Mississippi Drive West, Muscatine, IA
Stay at this 4-star business-friendly hotel in Muscatine. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Riverside Park and Muscatine ...
9.4/10 Exceptional! (255 reviews)
"Just the best experience we had this year"

Reviewed on May 26, 2025

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The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
AmericInn by Wyndham Muscatine
AmericInn by Wyndham Muscatine
2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and ...
7.4/10 Good! (376 reviews)
"Very clean. The lady working at the front desk was very polite and helpful. We couldn’t get our tv to come on and she immediately took care of it. We would definitely stay there again."

Reviewed on May 25, 2025

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AmericInn by Wyndham Muscatine
Super 8 by Wyndham Muscatine
Super 8 by Wyndham Muscatine
2 out of 5
2900 N Highway 61, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
6.2/10 (270 reviews)
"Everything was great!"

Reviewed on Sep 30, 2024

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Super 8 by Wyndham Muscatine
Hampton Inn Muscatine
Hampton Inn Muscatine
2.5 out of 5
3303 N Port Drive, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Muscatine Municipal Golf ...
8.4/10 Very Good! (425 reviews)
"Good stay, but room had ants everywhere on first floor."

Reviewed on Jun 8, 2025

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Hampton Inn Muscatine
Comfort Inn Muscatine near Hwy 61
Comfort Inn Muscatine near Hwy 61
2.5 out of 5
115 Cleveland St, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
7.6/10 Good! (192 reviews)
"generally good"

Reviewed on Jun 9, 2025

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Comfort Inn Muscatine near Hwy 61
The Sage Hotel
The Sage Hotel
2 out of 5
2402 Park Ave, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
6.6/10 (48 reviews)
"Good owners, with a awesome charisma"

Reviewed on Jun 10, 2025

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The Sage Hotel
Strawberry Farm Bed & Breakfast
Strawberry Farm Bed & Breakfast
3 out of 5
3402 Tipton Rd, Muscatine, IA
Stay at this 3-star B&B in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Geneva Golf and Country Club and Discovery Park ...
"We enjoyed our stay, but I do wish the place was a little cleaner. The shared bathroom (upon our arrival) had small hairs all over the sink and vanity like someone had emptied their electric shaver over it. Also, the doors to the rooms, including the shared bathroom, have no locks on them. The breakfast ..."

Reviewed on Jun 6, 2022

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Strawberry Farm Bed & Breakfast
See all 292 properties in Muscatine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.