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Muscatine Flights as Low as $263
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Cheap Flights to Muscatine
Fall in love at first flight with your vacation to Muscatine by saving a ton of cash on your last-minute cheap flight. There ’s no more scouring the internet for a good deal—book your flight to Muscatine on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Muscatine, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Muscatine
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Muscatine with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the MLI airport.
What is the cheapest month to fly to Muscatine?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Muscatine are in May, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Muscatine?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 11 to choose from for your flight to Muscatine.
What airport is best to fly into Muscatine?
When you’re planning your trip to Muscatine, convenience is the name of the game. Luckily, Muscatine Quad City Intl. Airport is nearby so you can deplane and get going on checking off everything on your Muscatine must-do list.
How much are flights to Muscatine?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Muscatine on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $263, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Muscatine?
The trick to saving a stack of cash on your flight to Muscatine? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $263 right now, why wait?
Destination airport | Quad City Intl. |
|---|---|
Destination airport IATA code | MLI |
Roundtrip price | $263 |
Last Minute Hotel Deals in Muscatine

Best Western Muscatine / Pearl City Hotel
The only complaint I have is the bed was pretty stiff, which isn't a big deal. Will be staying here again!
Reviewed on Apr 29, 2026

Strawberry Farm Bed & Breakfast
We had our choices of whatever we wanted for breakfast. It was perfect!
Reviewed on Oct 28, 2025

AmericInn by Wyndham Muscatine
Very clean and comfortable. Seemed like a very safe area. Didn’t have time to get to the pool, but I did look in and it was clean as well.
Reviewed on Apr 28, 2026

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
We were there for a wedding and the hotel and service were excellent. As far as the food was concerned, my pork chop was not the best but my wife's chicken was delicious. This is a very nice hotel.
Reviewed on Mar 29, 2026

Hampton Inn Muscatine

The Sage Hotel
Was not
Reviewed on Apr 26, 2026

Comfort Inn Muscatine near Hwy 61
Helpful staff. Clean rooms
Reviewed on Apr 8, 2026

Wyndham Moline on John Deere Commons
Great stay. Breakfast was great and excellent service.
Reviewed on Apr 27, 2026
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