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Hotels in Isla Santa María

Choose from 221 Isla Santa María Hotel Deals

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
  • 1 hour drive from Post Office Bay
Stay at this hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Las ...
9/10 Wonderful! (409 reviews)
"La atencion"

Reviewed on May 27, 2026

Hotel Fiesta
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
  • 1 hour drive from Post Office Bay
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful ...
10/10 Exceptional! (138 reviews)
"Niko and his staff were VERY helpful and kind. They made breakfast from scratch every morning. If you couldn’t make breakfast due to a tour, you just had to tell him and he’d make a box lunch instead. He also gave us recommendations for places to eat and his phone number if needed. The Maidith was ..."

Reviewed on Jun 1, 2026

Maidith Galapagos Inn
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada Puerto Ayora Galapagos
  • 1 hour drive from Post Office Bay
Book a stay at this luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
9.4/10 Exceptional! (99 reviews)
"Highly recomended"

Reviewed on May 1, 2026

Finch Bay Galapagos Hotel
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
  • 1 hour drive from Post Office Bay
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (205 reviews)
"Away from loud noise. Rooms are always cleaned. Staff are very helpful, courteous, friendly. Breakfast choices are simple , good and healthy. Amenities are minimal, Just no elevator, but tolerable. 3-5 ninutes to town by taxi $2.00 (yes $2.00). This would have cost me $5-7 in L.A. I will definitely ..."

Reviewed on Jun 2, 2026

Hotel el descanso del Guia
Ikala Galapagos Hotel

Ikala Galapagos Hotel

4 out of 5
Tomas de Berlanga 110 y Moises Brito Puerto Ayora Ecuador
  • 1 hour drive from Post Office Bay
Book a stay at this business-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff and ...
9.6/10 Exceptional! (147 reviews)
"We stayed here for 4 nights and really liked it. All of the staff were very pleasant, professional, friendly and accommodating. One of the servers at the breakfast buffet even ran down the street to get an avocado for my vegan niece!! The beautiful restaurant is located on the roof top with nice ..."

Reviewed on May 12, 2026

Ikala Galapagos Hotel
Hotel Cucuve

Hotel Cucuve

4 out of 5
Charles Binford 083 y Ave Charles Darwin Puerto Ayora
  • 1 hour drive from Post Office Bay
Stay at this B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (293 reviews)
"We loved our stay at Hotel Cucuve. The interior design of the hotel and all it’s spaces are really beautiful. The finishes. Nice. The staff are super friendly, kind, and helpful. The room was great. The bed comfortable. The bathroom nicely sized with a great shower. We also had a big balcony in our ..."

Reviewed on Jun 1, 2026

Hotel Cucuve
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos Puerto Ayora Galapagos
  • 1 hour drive from Post Office Bay
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are located ...
9.8/10 Exceptional! (74 reviews)
"Great hotel adjacent to downtown area of puerto Ayora. Staff was fantastic and helpful. Pool area was great and helpful for the kids to play (note there is no beach in town, it’s outside of town). Poolside bar was a nice touch as well. Had bikes to loan and a kayak for the lagoon it sits on. We loved ..."

Reviewed on May 29, 2026

El Barranco Galapagos
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

4 out of 5
Ave. Charles Darwin S/n Y Piquero Puerto Ayora Galapagos
  • 1 hour drive from Post Office Bay
Book a stay at this business-friendly hotel in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in ...
8.8/10 Excellent! (130 reviews)
"Charming hotel right on the water. Seals and crabs in our breakfast view."

Reviewed on Mar 30, 2026

Blu Galapagos Sustainable Waterfront Lodge
Posada del Mar

Posada del Mar

3 out of 5
Thomas de Berlanga 217 y Av. Baltra Puerto Ayora Islas Galápagos
  • 1 hour drive from Post Office Bay
Stay at this hotel in Puerto Ayora. Enjoy breakfast (surcharge), daily housekeeping, and dry cleaning or laundry services. Our guests praise the helpful staff ...
9.8/10 Exceptional! (241 reviews)
"Excellent staff, excellent property, very close to everything. You will love it."

Reviewed on May 26, 2026

Posada del Mar
Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos

3 out of 5
18 de Febrero y Seymour Puerto Ayora Islas Galápagos
  • 1 hour drive from Post Office Bay
Stay at this hotel in Puerto Ayora. Enjoy breakfast (surcharge), room service, and onsite spa services. Popular attractions Tortuga Bay Beach and Fishing Piers ...
9.6/10 Exceptional! (47 reviews)
"Nice clean hotel with a decent pool and restaurant. Walkable."

Reviewed on May 21, 2026

Fernandina Hotel & Spa Galápagos
Hotel Ninfa

Hotel Ninfa

3.5 out of 5
Settlers and Thomas de Berlanga Puerto Ayora Galapagos
  • 1 hour drive from Post Office Bay
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, room service, and a 24-hour front desk. Popular attractions Malecon and Gus Angermeyer Ferry Terminal ...
8.4/10 Very Good! (243 reviews)
"Excelente ubicación y servicio del personal, las suites estan remodeladas, los desayunos son buffet, muy variado."

Reviewed on May 29, 2026

Hotel Ninfa
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

3.5 out of 5
Punta Estrada Puerto Ayora Galapagos
  • 1 hour drive from Post Office Bay
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Playa ...
9.4/10 Exceptional! (136 reviews)
"Beautiful hotel, with friendly welcoming staff, awesome choice of meals, definitely recommend it! Easy to get to the town, a beach closeby and spacious rooms facing the waters....plenty of wildlife around"

Reviewed on May 14, 2026

Angermeyer Waterfront Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Isla Santa María

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Frequently Asked Questions About Isla Santa María hotels

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How many hotels are there in Isla Santa María?

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