Hotels Near
Mission District

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Featured Mission District Hotels

King George Hotel
King George Hotel
3 out of 5
334 Mason Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Francisco. Enjoy a 24-hour front desk, daily housekeeping, and conference space. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,594 reviews)
"Nice place to stay—missed the bar being not opened"

Reviewed on Jun 1, 2024

King George Hotel
Holiday Inn Golden Gateway, an IHG Hotel
Holiday Inn Golden Gateway, an IHG Hotel
3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
Fully refundable
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the pool ...
8.6/10 Excellent! (2,599 reviews)
"Staff nice and helpful, great location."

Reviewed on Jun 2, 2024

Holiday Inn Golden Gateway, an IHG Hotel
Hotel Riu Plaza Fisherman's Wharf
Hotel Riu Plaza Fisherman's Wharf
4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (6,248 reviews)
"There are very convenient location, delicious breakfast, pleasant atmosphere inside and around property"

Reviewed on Jun 1, 2024

Hotel Riu Plaza Fisherman's Wharf
Club Quarters Hotel in San Francisco
Club Quarters Hotel in San Francisco
4 out of 5
424 Clay St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and ...
8.6/10 Excellent! (1,597 reviews)
"good value"

Reviewed on May 31, 2024

Club Quarters Hotel in San Francisco
Handlery Union Square Hotel
Handlery Union Square Hotel
3.5 out of 5
351 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.6/10 Excellent! (1,908 reviews)
Fantastic Location
"The location was fantastic. Literally 20 steps from a cable car stop that took to you some famous landmarks. You could walk 2 blocks and get tickets if you didn’t already have the muni app."

Reviewed on May 30, 2024

Handlery Union Square Hotel
The Westin St. Francis San Francisco on Union Square
The Westin St. Francis San Francisco on Union Square
4.5 out of 5
335 Powell Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the ...
8.8/10 Excellent! (2,741 reviews)
"Very pleasant staff. So helpful."

Reviewed on Jun 2, 2024

The Westin St. Francis San Francisco on Union Square
The Marker San Francisco
The Marker San Francisco
4 out of 5
501 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
8.4/10 Very Good! (1,007 reviews)
"Great Location and style"

Reviewed on May 29, 2024

The Marker San Francisco
Hotel Caza Fisherman's Wharf
Hotel Caza Fisherman's Wharf
4 out of 5
1300 Columbus Avenue, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (3,596 reviews)
"Nice"

Reviewed on Jun 3, 2024

Hotel Caza Fisherman's Wharf
Hilton San Francisco Financial District
Hilton San Francisco Financial District
4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (36 reviews)
"It was an eazy check-in. The room was clean and had a great view. We felt safe walking around and was close to public transportation that we used to go to the giants stadium."

Reviewed on May 31, 2024

Hilton San Francisco Financial District
Hyatt Regency San Francisco
Hyatt Regency San Francisco
4 out of 5
5 Embarcadero Center, San Francisco, CA
Fully refundable
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,912 reviews)
"Clean"

Reviewed on Jun 3, 2024

Hyatt Regency San Francisco
Chancellor Hotel on Union Square
Chancellor Hotel on Union Square
3.5 out of 5
433 Powell St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and a business center. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,891 reviews)
"Easy check-in, cheap deposit, and bed/pillows were comfy. The bartender was super sweet, too!"

Reviewed on Jun 2, 2024

Chancellor Hotel on Union Square
Hotel Zephyr San Francisco
Hotel Zephyr San Francisco
4 out of 5
250 Beach Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,539 reviews)
"In place but be aware of the extra amenity fee when you leave"

Reviewed on Jun 1, 2024

Hotel Zephyr San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Mission District

San Francisco is a city that has a lot going on, but you have your sights set on Mission District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Mission District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Mission District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Francisco so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Mission District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Mission District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Mission District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Mission District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $95
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Mission District hotel you want, book it, and never look back. Because your great escape is ahead of you.