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Hotels in Santee

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Last Minute Hot Rate® Hotel Deals in Santee

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Choose from 203 Santee Hotel Deals

Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5
8929 Old Number Six Highway, Santee, SC
  • 6 min drive from Santee State Park
The price is $59 per night from Apr 28 to Apr 29
$59
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
6.6/10 (205 reviews)
excellent service, rest so-so
"only 1 person desk at busy time. When second person came in they changed our room(frig did not work) Second room ok. No coffee cups. Breakfast was mediocre."

Reviewed on Mar 30, 2024

Quality Inn & Suites
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
  • 7 min drive from Santee State Park
The price is $75 per night from Apr 28 to Apr 29
$75
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (1,315 reviews)
"Basic hotel with good service and a friendly staff. Breakfast could have been better. Room was clean and comfortable."

Reviewed on Apr 15, 2024

Baymont by Wyndham Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
  • 7 min drive from Santee State Park
The price is $123 per night from May 5 to May 6
$123
per night
May 5 - May 6
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Santee Cooper Country Club and Santee Outlets ...
8.8/10 Excellent! (85 reviews)
"Very good stopping point on the way back North from Florida. Clean, comfortable. Easy access on and off of I-95."

Reviewed on Apr 17, 2024

Tru By Hilton Santee
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
  • 7 min drive from Santee State Park
The price is $133 per night from May 19 to May 20
$133
per night
May 19 - May 20
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (830 reviews)
"Nice hotel, friendly staff, convenient to I-95 but not too close."

Reviewed on Apr 10, 2024

Comfort Inn & Suites Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $156 per night from Apr 28 to Apr 29
$156
per night
Apr 28 - Apr 29
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (972 reviews)
"A very nice choice for a pet friendly stay."

Reviewed on Apr 12, 2024

Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $147 per night from May 19 to May 20
$147
per night
May 19 - May 20
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,000 reviews)
"Quick check in staff very professional"

Reviewed on Apr 15, 2024

Hampton Inn Santee-I-95
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2 out of 5
9117 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $60 per night from May 19 to May 20
$60
per night
May 19 - May 20
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
6.8/10 (471 reviews)
"It just seems very empty around the property however very convenient right of the highway"

Reviewed on Apr 14, 2024

Travelodge by Wyndham Santee
Holiday Inn Santee, an IHG Hotel
Holiday Inn Santee, an IHG Hotel
3 out of 5
139 Bradford Blvd, Santee, SC
  • 6 min drive from Santee State Park
The price is $159 per night from May 1 to May 2
$159
per night
May 1 - May 2
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast. Our guests praise the restaurant and the helpful staff in our reviews. ...
8/10 Very Good! (733 reviews)
"Stayed for a night to meet my sister and her family. Had a good time"

Reviewed on Apr 14, 2024

Holiday Inn Santee, an IHG Hotel
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
  • 7 min drive from Santee State Park
The price is $136 per night from May 6 to May 7
$136
per night
May 6 - May 7
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and WiFi. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,000 reviews)
A good place to stop.
"An older motor-hotel style property, it is well maintained and has been updated. A great place for a stopover, being convenient in location and pet friendly."

Reviewed on Apr 12, 2024

Best Western Plus Santee Inn
Red Roof Inn Santee
Red Roof Inn Santee
2 out of 5
9091 Old Hwy 6, Santee, SC
  • 6 min drive from Santee State Park
The price is $65 per night from Apr 22 to Apr 23
$65
per night
Apr 22 - Apr 23
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
6.4/10 (551 reviews)
"We were headed back north from Florida and it was a nice, quiet place to stop It was clean. It could use a little paint in the room but great for the price. Breakfast was good"

Reviewed on Apr 6, 2024

Red Roof Inn Santee
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2 out of 5
9125 Old Highway 6, Santee, SC
  • 7 min drive from Santee State Park
The price is $75 per night from Apr 21 to Apr 22
$75
per night
Apr 21 - Apr 22
Stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Santee ...
6.6/10 (390 reviews)
"Size of the room"

Reviewed on Apr 8, 2024

Super 8 by Wyndham Santee
Rodeway Inn Santee I-95
Rodeway Inn Santee I-95
2 out of 5
123 Mall Street, Santee, SC
  • 7 min drive from Santee State Park
The price is $72 per night from May 6 to May 7
$72
per night
May 6 - May 7
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and breakfast. Popular attractions Santee Cooper Country Club and Santee Outlets are located nearby. ...
6.2/10 (497 reviews)
Review
"Room #1 - was a little disappointing as it was not totally smoke free. Cigarette smoke could be smelled as soon as you entered. Once the bathroom exhaust fan & A/C fan came on the smoke was stronger. There were also items that were broken or hanging off the wall. Then came a group of people associating ..."

Reviewed on Apr 14, 2024

Rodeway Inn Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Santee

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Santee hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santee.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santee’s 203 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Santee hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santee. No matter your reason for visiting Santee, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Santee hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santee for as low as $59.

How many hotels are there in Santee?

With over 203 hotels in Santee, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in Santee?

Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Santee now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Santee right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.