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Tonight Mar 29 - Mar 30This weekend Mar 29 - Mar 31

Choose from 445 Rochester Hotel Deals

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
  • 11 min drive from Mayo Clinic
The price is $80 per night from Mar 30 to Mar 31
$80
per night
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,002 reviews)
"Very kind staff , clean , very reasonably priced!!!"

Reviewed on Mar 27, 2024

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
The price is $139 per night from Mar 30 to Mar 31
$139
per night
Mar 30 - Mar 31
Stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 3 restaurants, and breakfast. Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (1,022 reviews)
room comment
"I am not happy with the room structure"

Reviewed on Mar 26, 2024

Kahler Grand Hotel
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
  • 17 min walk from Mayo Clinic
The price is $110 per night from Apr 20 to Apr 21
$110
per night
Apr 20 - Apr 21
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (532 reviews)
"I really liked the Yoga mat and the exercise videooptions I was surprised that it was 10 blocks from the Clinic> My research indicated it was 5 min walking distance. It WAS easy walking distance to St.Mary's Hopital, but not the Clinic I was going to. But, the shuttle service to and from was ..."

Reviewed on Mar 25, 2024

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 3 min walk from Mayo Clinic
The price is $129 per night from Mar 30 to Mar 31
$129
per night
Mar 30 - Mar 31
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a fitness center, and onsite parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,186 reviews)
"Easy access to Mayo via subway. Caribou Coffee is in lounge area. Hotel itself is always clean but does need updating"

Reviewed on Mar 23, 2024

Kahler Inn and Suites - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $82 per night from Apr 3 to Apr 4
$82
per night
Apr 3 - Apr 4
Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (235 reviews)
"Was confusing to get to the pool, and disappointed that the pool opens at 10:00 am. Other hotels I've stayed at the pool opens at 6:00 am. Was hoping to go for a swim before the State Archery Meet, but sadly couldn't."

Reviewed on Mar 24, 2024

AmericInn by Wyndham Rochester Near Mayo Clinic
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.5 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $113 per night from Apr 7 to Apr 8
$113
per night
Apr 7 - Apr 8
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the ...
9/10 Wonderful! (503 reviews)
"We use to stay at the TownPlace Suites but the prices went up so we tried this new hotel. Better price, great breakfast, clean rooms and great service. Just as close to Mayo Gonda building but a bit further to St. Mary’s. Wonderful pizza restaurant across the street too. May be our new fav."

Reviewed on Mar 23, 2024

Hyatt House Rochester/Mayo Clinic Area
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 out of 5
1755 S Broadway, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $100 per night from Apr 20 to Apr 21
$100
per night
Apr 20 - Apr 21
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,015 reviews)
"Staff were friendly and helpful !"

Reviewed on Mar 25, 2024

Hampton Inn Rochester-South
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 out of 5
220 S Broadway, Rochester, MN
  • 6 min walk from Mayo Clinic
The price is $105 per night from Apr 20 to Apr 21
$105
per night
Apr 20 - Apr 21
Stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast. Our guests praise the restaurant and the helpful staff ...
8.8/10 Excellent! (503 reviews)
"Thanks. Expensive but decent hotel."

Reviewed on Mar 24, 2024

Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
  • 8 min walk from Mayo Clinic
The price is $123 per night from Mar 30 to Mar 31
$123
per night
Mar 30 - Mar 31
Stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. Popular ...
8/10 Very Good! (974 reviews)
"I didn’t realize it was exterior entry. It was clean and comfortable."

Reviewed on Mar 25, 2024

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3 out of 5
601 2ND STREET SW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $114 per night from Apr 4 to Apr 5
$114
per night
Apr 4 - Apr 5
Stay at this 3-star hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (255 reviews)
Nice hotel but not well maintained
"Location very convenient if you go to Mayo Clinic, Good size of the room, modern style. Basement parking (extra charge) . Bed not comfortable, I thought it’s new hotel but the mattress is not like new, or maybe just new name and remodel but they used the old hotel stuff, i’m not sure. Just little ..."

Reviewed on Mar 18, 2024

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Brentwood Inn & Suites
Brentwood Inn & Suites
2.5 out of 5
123 Fourth Ave. NW, Rochester, MN
  • 5 min walk from Mayo Clinic
The price is $109 per night from Apr 6 to Apr 7
$109
per night
Apr 6 - Apr 7
Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and onsite parking. Our guests praise the helpful staff and the convenient ...
8.4/10 Very Good! (1,000 reviews)
"The property could use some updates like a new exterior paint job. And the rooms could use new carpeting. Also your WI-FI security is weak. But for the price it was a good value."

Reviewed on Mar 16, 2024

Brentwood Inn & Suites
GuestHouse Inn & Suites Rochester
GuestHouse Inn & Suites Rochester
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
The price is $86 per night from Mar 31 to Apr 1
$86
per night
Mar 31 - Apr 1
Stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
7.6/10 Good! (1,009 reviews)
"Just an overnite stay needed for appointments at Mayo Clinic, provided needed comfort and rest. The parking lot and walkway were nicely plowed, shovelled following the wet snowfall. Easy drive to clinic,(the shuttle didn't work with schedule). Found great place to eat at the Boulder Tap House located ..."

Reviewed on Mar 27, 2024

GuestHouse Inn & Suites Rochester
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Rochester

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Finding a cheap car rental deal in Rochester is as easy as scoring cheap hotels in Rochester. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Rochester now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Rochester right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.