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Hotels in Opelousas

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Last Minute Hot Rate® Hotel Deals in Opelousas

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Choose from 373 Opelousas Hotel Deals

Smart Stay Inn
Smart Stay Inn
2 out of 5
1620 N University Ave, Lafayette, LA
  • 37 min drive from St. Landry Extended Care Hospital
The price is $53 per night from Apr 21 to Apr 22
$53
per night
Apr 21 - Apr 22
Stay at this hotel in Lafayette. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cajundome and Moore Park are located nearby. Discover ...
8.6/10 Excellent! (55 reviews)
VERY Good overnight stay!
"Recently refurbished, room was very comfortable and quiet facing the courtyard. Very easy on and off the I-10. The outer edge of the parking lot when walked was 1/4 mile. The pool has not been updated yet, so should not be listed as available until it is."

Reviewed on Apr 16, 2024

Smart Stay Inn
Evangeline Downs Hotel, Ascend Hotel Collection
Evangeline Downs Hotel, Ascend Hotel Collection
3 out of 5
2235 Creswell Ln Ext, Lot B, Opelousas, LA
  • 9 min drive from St. Landry Extended Care Hospital
The price is $90 per night from May 12 to May 13
$90
per night
May 12 - May 13
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (544 reviews)
"The entryway is beautiful and unique. The staff at check in and check out were amazing . Our room was pretty large with a pull out couch. The room was clean.The pool and spa were closed for most of our stay but was cleaned and fixed pretty quickly. The elevator shutters it is a little unnerving. ..."

Reviewed on Apr 3, 2024

Evangeline Downs Hotel, Ascend Hotel Collection
Holiday Inn Express & Suites Opelousas, an IHG Hotel
Holiday Inn Express & Suites Opelousas, an IHG Hotel
3 out of 5
5696 I-49 N Service Rd, Opelousas, LA
  • 8 min drive from St. Landry Extended Care Hospital
The price is $115 per night from May 12 to May 13
$115
per night
May 12 - May 13
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Louisiana Orphan Train Museum ...
8.8/10 Excellent! (78 reviews)
"Clean with great staff and breakfast"

Reviewed on Apr 16, 2024

Holiday Inn Express & Suites Opelousas, an IHG Hotel
Days Inn & Suites by Wyndham Opelousas
Days Inn & Suites by Wyndham Opelousas
2 out of 5
5761 I-49 S Service Rd, Opelousas, LA
  • 7 min drive from St. Landry Extended Care Hospital
The price is $72 per night from Apr 22 to Apr 23
$72
per night
Apr 22 - Apr 23
Stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
6.4/10 (536 reviews)
Bring a cover!
"Employee that checked me in was very friendly. Room was clean. Room was updated but bathroom has couple updates needed like the bar inside shower was broken and tub was old but was clean. Only problem was no cover. I froze all night because there was only a sheet and the thin top bed spread. I had ..."

Reviewed on Apr 13, 2024

Days Inn & Suites by Wyndham Opelousas
Hampton Inn Opelousas
Hampton Inn Opelousas
2.5 out of 5
1700 Commerce Blvd, Opelousas, LA
  • 9 min drive from St. Landry Extended Care Hospital
The price is $116 per night from May 19 to May 20
$116
per night
May 19 - May 20
Stay at this hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Louisiana Orphan Train Museum and St. Landry Catholic ...
8.4/10 Very Good! (291 reviews)
"excellent, friendly staff"

Reviewed on Apr 12, 2024

Hampton Inn Opelousas
Quality Inn Opelousas
Quality Inn Opelousas
2.5 out of 5
5454 I-49 North Service Rd., Opelousas, LA
  • 7 min drive from St. Landry Extended Care Hospital
The price is $89 per night from Apr 21 to Apr 22
$89
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our reviews. ...
7.4/10 Good! (297 reviews)
"I enjoyed everything about this hotel will be coming back!"

Reviewed on Sep 17, 2023

Quality Inn Opelousas
Studio 6 Opelousas, LA
Studio 6 Opelousas, LA
2 out of 5
5791 I-49 S Service Road, Opelousas, LA
  • 7 min drive from St. Landry Extended Care Hospital
The price is $60 per night from Apr 22 to Apr 23
$60
per night
Apr 22 - Apr 23
Stay at this hotel in Opelousas. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Louisiana Orphan Train Museum and St. Landry Catholic ...
5.2/10 (200 reviews)
"Everything"

Reviewed on Feb 26, 2024

Studio 6 Opelousas, LA
Motel 6 Opelousas, LA
Motel 6 Opelousas, LA
2 out of 5
4165 I-49 S Service Rd, Opelousas, LA
  • 7 min walk from St. Landry Extended Care Hospital
The price is $71 per night from Apr 21 to Apr 22
$71
per night
Apr 21 - Apr 22
Stay at this motel in Opelousas. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Louisiana Orphan Train Museum and St. Landry Catholic ...
6.8/10 (238 reviews)
"The bed was not comfortable."

Reviewed on Mar 13, 2024

Motel 6 Opelousas, LA
Microtel Inn & Suites by Wyndham Scott/Lafayette
Microtel Inn & Suites by Wyndham Scott/Lafayette
2 out of 5
301 Ambassador Caffery Pkwy, Scott, LA
  • 39 min drive from St. Landry Extended Care Hospital
The price is $57 per night from Apr 22 to Apr 23
$57
per night
Apr 22 - Apr 23
Stay at this hotel in Scott. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,003 reviews)
"Good"

Reviewed on Apr 16, 2024

Microtel Inn & Suites by Wyndham Scott/Lafayette
DoubleTree by Hilton Hotel Lafayette
DoubleTree by Hilton Hotel Lafayette
4 out of 5
1521 W Pinhook Rd, Lafayette, LA
  • 46 min drive from St. Landry Extended Care Hospital
The price is $118 per night from Apr 21 to Apr 22
$118
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Lafayette. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (1,004 reviews)
Nice area
"It was a nice stay the staff was very friendly. Good bartender Overall it was very nice"

Reviewed on Apr 17, 2024

DoubleTree by Hilton Hotel Lafayette
La Quinta Inn & Suites by Wyndham Lafayette Oil Center
La Quinta Inn & Suites by Wyndham Lafayette Oil Center
2.5 out of 5
1321 W Pinhook Rd, Lafayette, LA
  • 46 min drive from St. Landry Extended Care Hospital
The price is $94 per night from Apr 30 to May 1
$94
per night
Apr 30 - May 1
Stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,001 reviews)
Best By Far
"Customer service was phenomenal. The room was very clean. This is the best LaQuinta that I have ever reserved."

Reviewed on Apr 17, 2024

La Quinta Inn & Suites by Wyndham Lafayette Oil Center
Drury Inn & Suites Lafayette, LA
Drury Inn & Suites Lafayette, LA
3 out of 5
120 Alcide Dominique, Lafayette, LA
  • 38 min drive from St. Landry Extended Care Hospital
The price is $117 per night from Apr 29 to Apr 30
$117
per night
Apr 29 - Apr 30
Stay at this 3-star business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Great stay"

Reviewed on Apr 17, 2024

Drury Inn & Suites Lafayette, LA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Opelousas

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Opelousas.

Choosing the right hotel in Louisiana has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Opelousas’s 373 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $44. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Opelousas hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Opelousas. No matter your reason for visiting Opelousas, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Opelousas hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Opelousas for as low as $44.

How many hotels are there in Opelousas?

With over 373 hotels in Opelousas, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $44.

How to find cheap car rentals in Opelousas?

Finding a cheap car rental deal in Opelousas is as easy as scoring cheap hotels in Opelousas. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Opelousas now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Opelousas right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.