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Mission Bay Vacations

Pack those stellar shades. We have Mission Bay vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Mission Bay – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Mission Bay vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Mission Bay

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Mission Bay vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Mission Bay well.

Mission Bay Flight + Hotel packages

Top Hotel Deals

See all 1,591 Hotels in Mission Bay
The Dana on Mission Bay

The Dana on Mission Bay

1710 W Mission Bay Dr, San Diego
    3.5 out of 5.0
     
     

    Adjacent to San Diego's Mission Bay, this 13-acre hotel is within 2 miles of SeaWorld and Mission Beach, and 6 miles of the San Diego Zoo.

    The Dana on Mission Bay$119

    The Dana on Mission Bay$119
    Paradise Point Resort & Spa

    Paradise Point Resort & Spa

    1404 Vacation Rd, San Diego
      4.0 out of 5.0
       
       

      Paradise Point Resort & Spa is on a private tropical island in San Diego’s Mission Bay. SeaWorld® is a 4-minute drive away over Mission Bay’s South Cove, and ...

      Paradise Point Resort & Spa$103

      Paradise Point Resort & Spa$103
      Hyatt Regency Mission Bay Spa and Marina

      Hyatt Regency Mission Bay Spa and Marina

      1441 Quivira Rd, San Diego
        4.0 out of 5.0
         
         

        Located on the shores of San Diego's Mission Bay, the Hyatt Regency Mission Bay Spa and Marina is a quarter-mile from SeaWorld and Mission Beach, and 3 miles ...

        Hyatt Regency Mission Bay Spa and Marina$123

        Hyatt Regency Mission Bay Spa and Marina$123
        Hilton San Diego Resort & Spa

        Hilton San Diego Resort & Spa

        1775 E Mission Bay Dr, San Diego
          4.0 out of 5.0
           
           

          Bayside resort

          Hilton San Diego Resort & Spa$129

          Hilton San Diego Resort & Spa$129
          Avalonbay 2 Condo by RedAwning

          Avalonbay 2 Condo by RedAwning

          2719 Bayside Walk, San Diego
            4.0 out of 5.0
             
             

            Situated in San Diego, this condo building is close to Dog Beach, SeaWorld, and Ocean Beach Park. Also nearby are Mission Beach and Belmont Park.

            Avalonbay 1 Condo by RedAwning

            Avalonbay 1 Condo by RedAwning

            2719 Bayside Walk, San Diego
              3.5 out of 5.0
               
               

              Situated in San Diego, this condo building is close to Dog Beach, SeaWorld, and Ocean Beach Park. Also nearby are Mission Beach and Belmont Park.

              Town and Country San Diego

              Town and Country San Diego

              500 Hotel Circle North, San Diego
                3.5 out of 5.0
                 
                 

                Comprising 32 acres, this resort and conference center is next to the 27-hole Riverwalk Golf Club; Old Town, Balboa Park, SeaWorld San Diego, and the world famous ...

                Town and Country San Diego$80

                Town and Country San Diego$80
                Hard Rock Hotel San Diego

                Hard Rock Hotel San Diego

                207 5th Ave, San Diego
                  4.0 out of 5.0
                   
                   

                  The Hard Rock Hotel is in the center of San Diego's bustling Gaslamp Quarter, with restaurants, bars, and nightlife. The San Diego Convention Center is across ...

                  Hard Rock Hotel San Diego$143

                  Hard Rock Hotel San Diego$143
                  Hilton San Diego Bayfront

                  Hilton San Diego Bayfront

                  1 Park Blvd, San Diego
                    4.0 out of 5.0
                     
                     

                    Rising 30 stories above San Diego Bay, this modern Hilton is adjacent to the San Diego Convention Center, across from Petco Park, and 3 blocks from the Gaslamp ...

                    Hilton San Diego Bayfront$161

                    Hilton San Diego Bayfront$161
                    Best Western Plus Island Palms Hotel & Marina

                    Best Western Plus Island Palms Hotel & Marina

                    2051 Shelter Island Dr, San Diego
                      3.0 out of 5.0
                       
                       

                      This hotel is set on Shelter Island, surrounded by San Diego Bay and a private marina; Old Town is 5 miles away, and downtown San Diego is within 6 miles.

                      Best Western Plus Island Palms Hotel & Marina$111

                      Best Western Plus Island Palms Hotel & Marina$111

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.