Hotels Near
Mira Mesa

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Featured Mira Mesa Hotels

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,538 reviews)
There were two on site restaurants. One was only open for breakfast, I believe it was close for refurbishment for dinner. The other restaurant was a little too high end for my grandkids. We had breakfast at the Barefoot Bar & Grill on our last day, it was very good and the outdoor seating right on ...

Reviewed on Apr 10, 2026

Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
8/10 Very Good! (3,379 reviews)
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Reviewed on Apr 11, 2026

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,531 reviews)
Location is great for Petco Park or Gaslamp district.

Reviewed on Apr 11, 2026

Hard Rock Hotel San Diego
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,407 reviews)
The walls are paper, thin and it seemed to be a place where a lot of people partied

Reviewed on Apr 11, 2026

Handlery Hotel
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,304 reviews)
Staff at check in was a little bit rude

Reviewed on Apr 11, 2026

DoubleTree by Hilton San Diego - Del Mar
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (1,352 reviews)
Clean room not loud beds are comfortable, enjoyed my stay over all

Reviewed on Apr 11, 2026

The DEXTRO Little Italy, BW Premier Collection
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,140 reviews)
Clean room, friendly knowledgeable staff

Reviewed on Apr 10, 2026

Wyndham San Diego Bayside
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (2,611 reviews)
Booked this property based on price, location and pool. We didn’t end up using the pool but I did see it being cleaned each morning. Location was central to the activities we chose to do and close to fancy mall that my daughter loved. There is no restaurant on the property but several hotels close ...

Reviewed on Apr 11, 2026

Days Inn by Wyndham San Diego Hotel Circle
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,867 reviews)
Great location

Reviewed on Apr 11, 2026

Manchester Grand Hyatt San Diego
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,900 reviews)
I really enjoyed my stay here. The staff was very helpful and friendly. The interior is all upgraded and nice. I would definitely stay here again

Reviewed on Apr 9, 2026

The Sofia Hotel
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,457 reviews)
0 customers supervises

Reviewed on Apr 11, 2026

Sheraton San Diego Resort
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,255 reviews)
Thought the property was really nice and conveniently located. The charge of $35 a night to park your car was excessive though. First time I have ever been charged at a hotel that wasn’t in the city center. With the parking fee and the resort fee it added nearly $50 a night to my stay that I wasn’t ...

Reviewed on Apr 11, 2026

The Dana on Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Mira Mesa

San Diego is a city that has a lot going on, but you have your sights set on Mira Mesa. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Mira Mesa has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Mira Mesa hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Mira Mesa underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Mira Mesa city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Mira Mesa cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Mira Mesa at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $94
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Mira Mesa hotel you want, book it, and never look back. Because your great escape is ahead of you.