Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion


Hotels in Midtown

See all 773 Properties in Midtown
La Maison in Midtown an urban bed and breakfast

La Maison in Midtown an urban bed and breakfast

2800 Brazos, Houston
    3.5 out of 5.0
     
     

    Located in Midtown, this bed & breakfast is within 2 mi (3 km) of Houston Museum District, Discovery Green, and George R. Brown Convention Center. Downtown Aquarium ...

    La Maison in Midtown an urban bed and breakfast$163

    La Maison in Midtown an urban bed and breakfast$163
    The Jamerican

    The Jamerican

    2717 Austin Street, Houston
      3.5 out of 5.0
       
       

      Located in Midtown, this vacation home is within 1 mi (2 km) of Houston Museum District, Discovery Green, and George R. Brown Convention Center. Toyota Center ...

      La Quinta Inn & Suites Houston Bush Intl Airport E

      La Quinta Inn & Suites Houston Bush Intl Airport E

      18201 Kenswick Drive, Humble
        2.5 out of 5.0
         
         

        Situated near the airport, this hotel is within 3 mi (5 km) of Kenswick Park, Humble Civic Center, and Schott Park. Humble Museum and Deerbrook Mall are also ...

        La Quinta Inn & Suites Houston Bush Intl Airport E$74

        La Quinta Inn & Suites Houston Bush Intl Airport E$74
        Hotel Derek Houston Galleria

        Hotel Derek Houston Galleria

        2525 West Loop S, Houston
          4.0 out of 5.0
           
           

          Hotel Derek keeps you "In the Loop" with its prominent 610 Westheimer location, with hundreds of shops, dining and entertainment options all within walking ...

          Hotel Derek Houston Galleria$89

          Hotel Derek Houston Galleria$89
          Hilton Americas - Houston

          Hilton Americas - Houston

          1600 Lamar Street, Houston
            4.0 out of 5.0
             
             

            Attached to the George R Brown convention center by sky bridge, Hilton Americas - Houston is across the street from Toyota Arena and 2 blocks from Minute Maid ...

            Hilton Americas - Houston$141

            Hilton Americas - Houston$141
            The Whitehall Houston

            The Whitehall Houston

            1700 Smith St, Houston
              4.0 out of 5.0
               
               

              Located in Downtown Houston, this romantic hotel is within 1 mi (2 km) of Houston Public Library, Discovery Green, and George R. Brown Convention Center. Downtown ...

              The Whitehall Houston$120

              The Whitehall Houston$120
              Club Quarters Hotel in Houston

              Club Quarters Hotel in Houston

              720 Fannin Street, Houston
                4.0 out of 5.0
                 
                 

                Club Quarters Hotel in Houston is a full-service hotel designed for business travelers, in downtown Houston. A short walk from the Houston Pavilions, the Theater ...

                Club Quarters Hotel in Houston$76

                Club Quarters Hotel in Houston$76
                Red Roof Inn Houston - IAH Airport/JFK BLVD

                Red Roof Inn Houston - IAH Airport/JFK BLVD

                15675 John F. Kennedy Blvd, Houston
                  2.0 out of 5.0
                   
                   

                  Situated near the airport, this motel is within 6 mi (10 km) of Crowley, W. E. "Bill" Park, Houston Grand Prix, and Houston Police Department Museum. Park at ...

                  Red Roof Inn Houston - IAH Airport/JFK BLVD$52

                  Red Roof Inn Houston - IAH Airport/JFK BLVD$52
                  Royal Sonesta Houston Galleria

                  Royal Sonesta Houston Galleria

                  2222 West Loop South, Houston
                    4.0 out of 5.0
                     
                     

                    Located in The Galleria, this hotel is 0.5 mi (0.9 km) from River Oaks District and 2.5 mi (4.1 km) from Memorial Park. Williams Tower and Gerald D. Hines Waterwall ...

                    Royal Sonesta Houston Galleria$109

                    Royal Sonesta Houston Galleria$109
                    Ramada by Wyndham Houston Intercontinental Airport East

                    Ramada by Wyndham Houston Intercontinental Airport East

                    6115 Will Clayton Parkway, Humble
                      3.5 out of 5.0
                       
                       

                      Situated near the airport, this hotel is within 3 mi (5 km) of Humble Civic Center, Kenswick Park, and Schott Park. Humble Museum is 3.1 mi (5 km) away.

                      Ramada by Wyndham Houston Intercontinental Airport East$61

                      Ramada by Wyndham Houston Intercontinental Airport East$61
                      Map

                      Midtown Hotel Guide

                      Search for hotels in Midtown on Hotwire. You can easily find your hotels in Midtown using one of the methods below:

                      • View our selection of featured hotels in Midtown
                      • Use the map to find hotels in the Midtown neighborhood you prefer
                      • Use the filters to see hotels in a specific area of Midtown, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Midtown
                      • Enter your travel dates to view the best deals on hotels in Midtown - while they last