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Main Street Hyannis Vacations

Pack those stellar shades. We have Main Street Hyannis vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Main Street Hyannis – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Main Street Hyannis vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Main Street Hyannis

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Main Street Hyannis vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Main Street Hyannis well.

Main Street Hyannis Flight + Hotel packages

Top Hotel Deals

See all 749 Hotels in Main Street Hyannis
Heritage House Hotel

Heritage House Hotel

259 Main Street, Hyannis
    2.5 out of 5.0
     
     

    Heritage House Hotel$60

    Heritage House Hotel$60
    Americas Best Value Inn and Suites Hyannis/Cape Cod

    Americas Best Value Inn and Suites Hyannis/Cape Cod

    206 Main St, Hyannis
      2.0 out of 5.0
       
       

      Located in the heart of Hyannis, this hotel is within a 10-minute walk of John F. Kennedy Hyannis Museum, Cape Cod Baseball Hall of Fame, and Hyannis Harbor. ...

      Americas Best Value Inn and Suites Hyannis/Cape Cod$63

      Americas Best Value Inn and Suites Hyannis/Cape Cod$63
      Cape Cod Inn

      Cape Cod Inn

      447 Main St, Hyannis
        2.0 out of 5.0
         
         

        Situated on the Strip, this motel is steps from Cape Cod Baseball Hall of Fame and John F. Kennedy Hyannis Museum. Cape Cod Carousel and St. Francis Xavier Church ...

        Cape Cod Inn$75

        Cape Cod Inn$75
        International Inn

        International Inn

        662 Main Street, Hyannis
          2.5 out of 5.0
           
           

          Located in the heart of Hyannis, this luxury hotel is within a 10-minute walk of Cape Cod Carousel, St. Francis Xavier Church, and Twin Brooks Golf Course. Cape ...

          International Inn$80

          International Inn$80
          Courtyard Resort Hyannis, a VRI resort

          Courtyard Resort Hyannis, a VRI resort

          460 Main St, Hyannis
            2.5 out of 5.0
             
             

            Located in the heart of Hyannis, this hotel is within a 5-minute walk of Cape Cod Baseball Hall of Fame, John F. Kennedy Hyannis Museum, and Cape Cod Carousel. ...

            Courtyard Resort Hyannis, a VRI resort$113

            Courtyard Resort Hyannis, a VRI resort$113
            Hyannis INN

            Hyannis INN

            473 MAIN ST, Hyannis
              2.0 out of 5.0
               
               
              Cape Codder Resort and Spa

              Cape Codder Resort and Spa

              1225 Iyannough Rd, Hyannis
                3.0 out of 5.0
                 
                 

                Situated near the airport, this spa resort is 1.2 mi (2 km) from Hyannis Golf Course and within 3 mi (5 km) of Coast Guard Heritage Museum and Barnstable Old ...

                Cape Codder Resort and Spa$129

                Cape Codder Resort and Spa$129
                Sea Crest Beach Hotel

                Sea Crest Beach Hotel

                350 Quaker Rd, North Falmouth
                  3.0 out of 5.0
                   
                   

                  This North Falmouth hotel is on the beach, 0 mi (0.1 km) from Old Silver Beach, and within 6 mi (10 km) of Wood Neck Beach and Cataumet Arts Center. Falmouth ...

                  Sea Crest Beach Hotel$169

                  Sea Crest Beach Hotel$169
                  Hyannis Travel Inn

                  Hyannis Travel Inn

                  18 North St, Hyannis
                    2.0 out of 5.0
                     
                     

                    Located in the heart of Hyannis, this hotel is steps from John F. Kennedy Hyannis Museum and Cape Cod Baseball Hall of Fame. Cape Cod Carousel and St. Francis ...

                    Hyannis Travel Inn$90

                    Hyannis Travel Inn$90
                    Bayside Resort Hotel

                    Bayside Resort Hotel

                    225 Route 28, West Yarmouth
                      3.0 out of 5.0
                       
                       

                      Bayside Resort Hotel is in West Yarmouth, less than 10 minutes’ drive from the airport in Hyannis, and within easy reach of Cape Cod. Guests have a great choice ...

                      Bayside Resort Hotel$120

                      Bayside Resort Hotel$120

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.