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Tonight Mar 29 - Mar 30This weekend Mar 29 - Mar 31

Choose from 65 Louisiana Hotel Deals

Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
2.5 out of 5
4141B MARKET ST, Hannibal, MO
  • 27 min drive from Mississippi River
The price is $51 per night from Apr 3 to Apr 4
$51
per night
Apr 3 - Apr 4
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.8/10 (64 reviews)
"Nice property for the price."

Reviewed on Mar 23, 2024

Howard Johnson BY Wyndham Hannibal
River's Edge Motel
River's Edge Motel
2 out of 5
201 Mansion St, Louisiana, MO
  • 16 min drive from Mississippi River
The price is $75 per night from Mar 30 to Mar 31
$75
per night
Mar 30 - Mar 31
Stay at this motel in Louisiana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (264 reviews)
Nice
"Older hotel but well cared for. Clean and friendly service."

Reviewed on Nov 4, 2023

River's Edge Motel
Best Western On The River
Best Western On The River
2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 30 min drive from Mississippi River
The price is $107 per night from Mar 31 to Apr 1
$107
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,005 reviews)
"The property is clean and seems well located if you are wanting to check out downtown Hannibal. Even though we had a first floor room next to the pool it was super quiet. Pool area looked nice but we didn’t use it. The hotel needs some updating though, feels like a hotel I would have stayed at on ..."

Reviewed on Mar 25, 2024

Best Western On The River
Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
2.5 out of 5
4000 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
The price is $80 per night from Mar 31 to Apr 1
$80
per night
Mar 31 - Apr 1
Stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (450 reviews)
Comfortable and Clean Stopover
"Easy Check in, comfortable bed, adequate breakfast. clean and tidy overall. Stop over hotel on a recent trip to Chicago. Impressed enough for value to book it again when we traveled back through."

Reviewed on Mar 25, 2024

Comfort Inn & Suites - Hannibal
Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 32 min drive from Mississippi River
The price is $107 per night from Mar 31 to Apr 1
$107
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (905 reviews)
"We tend to stay in Hannibal each year as we return from FL to IA. The SleepInn is very convenient,clean and quietwith good restaurant within walking distance"

Reviewed on Mar 26, 2024

Sleep Inn & Suites
Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 32 min drive from Mississippi River
The price is $94 per night from Apr 21 to Apr 22
$94
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
7.8/10 Good! (1,001 reviews)
"It was perfect for our one night stay."

Reviewed on Mar 21, 2024

Quality Inn & Suites Hannibal
Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 29 min drive from Mississippi River
The price is $54 per night from Apr 3 to Apr 4
$54
per night
Apr 3 - Apr 4
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (996 reviews)
"Other guests were loud, pool was closed, ice machine broke, vending machines broke"

Reviewed on Mar 8, 2024

Motel 6 Hannibal, MO
Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
2.5 out of 5
120 Shinn Lane, Hannibal, MO
  • 32 min drive from Mississippi River
The price is $129 per night from Mar 31 to Apr 1
$129
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (378 reviews)
"Everything was super smooth. Which I love!"

Reviewed on Mar 24, 2024

Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 29 min drive from Mississippi River
The price is $54 per night from Apr 4 to Apr 5
$54
per night
Apr 4 - Apr 5
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (1,006 reviews)
Great stay!
"Really nice facility in the river side hills.Quiet and very clean.Limited breakfast but that's fine.Got my corn flakes and coffee and there is a good restaurant right next door.Will definitely stay here again."

Reviewed on Mar 24, 2024

Super 8 by Wyndham Hannibal
Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
2 out of 5
4070 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
The price is $63 per night from Mar 31 to Apr 1
$63
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Sodalis Nature Preserve and Rockcliffe ...
7.2/10 Good! (47 reviews)
"Good location. Good value for money. Room is a little "dated". Road noise from the highway."

Reviewed on Mar 14, 2024

Days Inn by Wyndham Hannibal
Super 8 by Wyndham Bowling Green
Super 8 by Wyndham Bowling Green
2 out of 5
1216 E Champ Clark Dr, Bowling Green, MO
  • 36 min drive from Mississippi River
The price is $82 per night from Apr 21 to Apr 22
$82
per night
Apr 21 - Apr 22
Stay at this hotel in Bowling Green. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (420 reviews)
Recommend this place!!!!!
"We just needed a place to sleep for the night on our journey south, and this did not disappoint! Very comfortable bed, clean room, and hot breakfast!!!"

Reviewed on Mar 5, 2024

Super 8 by Wyndham Bowling Green
Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
2.5 out of 5
4141 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
The price is $63 per night from Mar 31 to Apr 1
$63
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
5.8/10 (508 reviews)
"Its a great place to stay"

Reviewed on Nov 5, 2023

Baymont by Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Louisiana

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Louisiana hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Louisiana.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Louisiana’s 65 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $51. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Louisiana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Louisiana. No matter your reason for visiting Louisiana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Louisiana hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Louisiana for as low as $51.

How many hotels are there in Louisiana?

With over 65 hotels in Louisiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $51.

How to find cheap car rentals in Louisiana?

Finding a cheap car rental deal in Louisiana is as easy as scoring cheap hotels in Louisiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Louisiana now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Louisiana right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.