Search for Cheap Deals onSpa Resort Hotels in Lake City
Photo by Ronald Wilson
Check Last Minute Lake City Hotel Deals
Tonight Jun 1 - Jun 2This weekend Jun 2 - Jun 4Next weekend Jun 9 - Jun 11You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking, and you save up to 60%!
Featured Lake City Resorts & Hotels with Spas

Baymont by Wyndham Lake City
3598 W Us Highway 90, Lake City, FL, 32055
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Best Western Plus Lake City
350 SW Florida Gateway Dr, Lake City, FL, 32024
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Comfort Suites Lake City
3690 W Us Highway 90, Lake City, FL, 32055
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Econo Lodge Live Oak
6811 N Us 129 & I 10, Live Oak, FL, 32060
Fully refundableReserve now, pay when you stay
Stay at this motel in Live Oak. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. Popular ...

Fairfield Inn & Suites Lake City
538 Sw Corporate Dr, Lake City, FL, 32024
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...

Hampton Inn & Suites Lake City
450 SW Florida Gateway Drive, Lake City, FL, 32024
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Holiday Inn & Suites Lake City, an IHG Hotel
213 Sw Commerce Dr, Lake City, FL, 32025
Fully refundable
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast. Our guests praise the pool and the helpful staff in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
Top Points of Interests in Lake City
- Hotels near North Florida Speedway
- Hotels near Lake City Mall
- Hotels near Southside Recreation Complex
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Southside Sports Complex
- Hotels near Florida Department of Transportation
- Hotels near Columbia County Courthouse
- Hotels near Pine Grove Baptist Church
- Hotels near Southern Oaks Golf Club
- Hotels near Lake City Columbia County Historical Museum
- Hotels near Epiphany Catholic Church
- Hotels near Lake DeSoto Farmers Market
- Hotels near Ginnie Spring
- Hotels near Ichetucknee Springs State Park
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Spirit of the Suwannee Music Park
- Hotels near Sante Fe College
- Hotels near Okefenokee National Wildlife Refuge
- Hotels near Ichetucknee River
- Hotels near Ichtucknee Family Canoes and Cabins
Cities near Lake City
- Gainesville Hotels (41.62 mi)
- Live Oak Hotels (21.81 mi)
- Gulf Coast Hotels (668.16 mi)
- Alachua Hotels (28.67 mi)
- High Springs Hotels (25.18 mi)
- Starke Hotels (35.9 mi)
- MacClenny Hotels (32.17 mi)
- Southeastern United States Hotels (199.27 mi)
- Central West Coast Florida Hotels (78.67 mi)
- Fort White Hotels (18.92 mi)
- Mayo Hotels (33.35 mi)
- Jasper Hotels (29.22 mi)
- Newberry Hotels (37.57 mi)
- Old Town Hotels (45.49 mi)
- Northern Florida Hotels (71 mi)
- Branford Hotels (23.48 mi)
- White Springs Hotels (12.02 mi)
- Southeast Georgia Hotels (119.33 mi)
- Northeast Florida Hotels (26.02 mi)
- Trenton Hotels (41.21 mi)
Car Rentals Near Lake City
- Car rentals in Gainesville
- Car rentals in Live Oak
- Car rentals in Gulf Coast
- Car rentals in Alachua
- Car rentals in High Springs
- Car rentals in Starke
- Car rentals in MacClenny
- Car rentals in Southeastern United States
- Car rentals in Central West Coast Florida
- Car rentals in Fort White
- Car rentals in Mayo
- Car rentals in Jasper
- Car rentals in Newberry
- Car rentals in Old Town
- Car rentals in Northern Florida
- Car rentals in Branford
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Lake City
- Tru by Hilton Lake City
- Comfort Suites Lake City
- Best Western Plus Lake City
- Holiday Inn & Suites Lake City, an IHG Hotel
- Days Inn by Wyndham Lake City I-10
- Americas Best Value Inn Lake City
- Knights Inn Lake City
- Days Inn by Wyndham Lake City I-75
- Baymont by Wyndham Lake City
- Home2 Suites by Hilton Lake City
- Fairfield Inn & Suites Lake City