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Historic Main Street Vacations

Pack those stellar shades. We have Historic Main Street vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Historic Main Street – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Historic Main Street vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Historic Main Street

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Historic Main Street vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Historic Main Street well.

Top Hotel Deals

See all 232 Hotels in Historic Main Street
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive, Maryland Heights
    3.5 out of 5.0
     
     

    Situated near the airport, this hotel is 1.4 mi (2.3 km) from Hollywood Casino Amphitheatre and within 9 mi (15 km) of Historic Main Street and Lindenwood University. ...

    Hollywood Casino & Hotel St. Louis$93

    Hollywood Casino & Hotel St. Louis$93
    Red Lion Hotel St Louis City Center

    Red Lion Hotel St Louis City Center

    400 S 14th St, St. Louis
      3.5 out of 5.0
       
       

      This historic 13-story St. Louis hotel is 1 block from Scottrade/Peabody Opera House Complex, 3 blocks from Union Station, and 5 blocks from Busch Stadium. The ...

      Red Lion Hotel St Louis City Center$91

      Red Lion Hotel St Louis City Center$91
      The Parkway Hotel

      The Parkway Hotel

      4550 Forest Park Ave, St. Louis
        3.0 out of 5.0
         
         

        Located in Central West End, this hotel is within a 15-minute walk of Barnes Jewish Hospital, World Chess Hall of Fame, and Cathedral Basilica of St. Louis. ...

        The Parkway Hotel$107

        The Parkway Hotel$107
        Clayton Plaza Hotel

        Clayton Plaza Hotel

        7750 Carondelet Avenue, St. Louis
          3.5 out of 5.0
           
           

          Surrounded by businesses, restaurants, and residences, the Clayton Plaza Hotel is 4 miles from Forest Park and the acclaimed St. Louis Zoo. Downtown St. Louis ...

          Clayton Plaza Hotel$100

          Clayton Plaza Hotel$100
          Motel 6 Hazelwood

          Motel 6 Hazelwood

          5781 Campus Ct, Hazelwood
            2.0 out of 5.0
             
             

            Situated near the airport, this motel is within 6 mi (10 km) of St. Louis Mills Mall, James S. McDonnell Prologue Room, and Payne-Gentry Historical House. Westport ...

            Motel 6 Hazelwood$36

            Motel 6 Hazelwood$36
            Moonrise Hotel

            Moonrise Hotel

            6177 Delmar Blvd, St. Louis
              4.0 out of 5.0
               
               

              Moonrise Hotel places guests amid the vibrant dining, shopping, and nightlife scene of St. Louis' Delmar Loop neighborhood. Guests are a 5-minute walk from Delmar ...

              Moonrise Hotel$148

              Moonrise Hotel$148
              Red Roof Plus St. Louis - Forest Park / Hampton Ave.

              Red Roof Plus St. Louis - Forest Park / Hampton Ave.

              5823 Wilson Avenue, St. Louis
                2.5 out of 5.0
                 
                 

                Red Roof Plus St. Louis - Forest Park / Hamilton Av is off highway I-44, in The Hill, St. Louis’s "Little Italy." It’s a 10-minute drive to St. Louis University, ...

                Red Roof Plus St. Louis - Forest Park / Hampton Ave.$81

                Red Roof Plus St. Louis - Forest Park / Hampton Ave.$81
                St. Louis Union Station Hotel, Curio Collection by Hilton

                St. Louis Union Station Hotel, Curio Collection by Hilton

                1820 Market Street, St. Louis
                  4.0 out of 5.0
                   
                   

                  This St. Louis hotel is in Union Station, one-quarter mile from the Scottrade Center, less than a mile from Busch Stadium, and about a mile from iconic Gateway ...

                  St. Louis Union Station Hotel, Curio Collection by Hilton$114

                  St. Louis Union Station Hotel, Curio Collection by Hilton$114
                  Renaissance St. Louis Airport Hotel

                  Renaissance St. Louis Airport Hotel

                  9801 Natural Bridge Road, Berkeley
                    4.0 out of 5.0
                     
                     

                    Renaissance St. Louis Airport Hotel, a half-mile from the St. Louis Airport, is 12 miles from downtown St. Louis and Busch Stadium.

                    Renaissance St. Louis Airport Hotel$94

                    Renaissance St. Louis Airport Hotel$94
                    Days Inn by Wyndham St. Louis/Westport MO

                    Days Inn by Wyndham St. Louis/Westport MO

                    1970 Craig Rd, Maryland Heights
                      2.5 out of 5.0
                       
                       

                      Near I-270, this suburban St Louis hotel is a half-mile from West Port Plaza, 4 miles from UMB Bank Pavilion, and 6 miles from Lambert-St Louis International ...

                      Days Inn by Wyndham St. Louis/Westport MO$72

                      Days Inn by Wyndham St. Louis/Westport MO$72

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.