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Last Minute Hot Rate® Hotel Deals in Florida Keys

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Choose from 7906 Florida Keys Hotel Deals

Coconut Cay Resort & Marina
Coconut Cay Resort & Marina
2 out of 5
7196 Overseas Highway, Marathon, FL
  • 2 hours drive from Duval Street
The price is $138 per night from May 20 to May 21
$138
per night
May 20 - May 21
Stay at this hotel in Marathon. Enjoy free parking, a marina, and free bicycles on site. Our guests praise the pool and the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (1,004 reviews)
"Son and I enjoyed our 1-night stay for a local event. Would stay again. They offer the bicycles and paddle boards. I would stay again. Pool was clean and well taken care of."

Reviewed on Apr 17, 2024

Coconut Cay Resort & Marina
Hawks Cay Resort
Hawks Cay Resort
4 out of 5
61 Hawks Cay Blvd, Marathon, FL
  • 2 hours drive from Duval Street
The price is $335 per night from Apr 29 to Apr 30
$335
per night
Apr 29 - Apr 30
Stay at this beach hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and 5 restaurants. Our guests praise the clean rooms and the family amenities in our ...
7.8/10 Good! (1,002 reviews)
"Beautiful property, not too crowded, plenty of room to enjoy amenities."

Reviewed on Apr 16, 2024

Hawks Cay Resort
Cheeca Lodge & Spa
Cheeca Lodge & Spa
4 out of 5
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
  • 3 hours drive from Duval Street
The price is $329 per night from May 6 to May 7
$329
per night
May 6 - May 7
Stay at this beach resort in Islamorada. Enjoy free parking, 3 outdoor pools, and 3 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
"We loved the beach and all of the facilities! It was so easy to park under our room with the golf course view. The property is gorgeous and well maintained. Also, Spa Island was so pretty and relaxing as well as the waterfall grotto pool and jacuzzi near our room. Loved the adult pool too! Daydrian ..."

Reviewed on Apr 16, 2024

Cheeca Lodge & Spa
Chesapeake Beach Resort
Chesapeake Beach Resort
2.5 out of 5
83409 Overseas Hwy, Islamorada, FL
  • 3 hours drive from Duval Street
The price is $199 per night from Apr 29 to Apr 30
$199
per night
Apr 29 - Apr 30
Stay at this beach hotel in Islamorada. Enjoy 2 outdoor pools, a private beach, and a 24-hour front desk. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,293 reviews)
"Our ocean front room was awesome! The views were spectacular. The entire staff was so polite and helpful. If I had to say one negative comment the breakfast was very week. The gentleman who ran the breakfast more than made up for it with his personal charm. I HIGHLY recommend this facility."

Reviewed on Apr 18, 2024

Chesapeake Beach Resort
Waterside Suites & Marina
Waterside Suites & Marina
3.5 out of 5
201 Ocean Drive, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $169 per night from Apr 21 to Apr 22
$169
per night
Apr 21 - Apr 22
Stay at this hotel in Key Largo. Enjoy a marina, WiFi, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (1,002 reviews)
"Most comfortable bed ever!"

Reviewed on Apr 16, 2024

Waterside Suites & Marina
Isla Bella Beach Resort & Spa
Isla Bella Beach Resort & Spa
5 out of 5
1 Knights Key Boulevard, MM 47, Marathon, FL
  • 2 hours drive from Duval Street
The price is $305 per night from May 5 to May 6
$305
per night
May 5 - May 6
Stay at this 5-star luxury hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"Very well laid out grounds, attractive vistas, needs more actual beach area."

Reviewed on Apr 15, 2024

Isla Bella Beach Resort & Spa
Faro Blanco Resort & Yacht Club
Faro Blanco Resort & Yacht Club
4 out of 5
1996 Overseas Highway, Marathon, FL
  • 2 hours drive from Duval Street
The price is $229 per night from Apr 29 to Apr 30
$229
per night
Apr 29 - Apr 30
Stay at this 4-star family-friendly hotel in Marathon. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (1,448 reviews)
"Very nice place to relax with no issues!! Food and beverage very good! Personal very attentive"

Reviewed on Apr 16, 2024

Faro Blanco Resort & Yacht Club
Reefhouse Resort & Marina
Reefhouse Resort & Marina
3.5 out of 5
103800 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $280 per night from May 13 to May 14
$280
per night
May 13 - May 14
Stay at this beach hotel in Key Largo. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular ...
9/10 Wonderful! (1,172 reviews)
"Resort has a very nice pool and beach area. Pool bar has great selection of special drinks. Multiple restaurant options on site. Rooms are spacious and bed quality was good. It’s quite pricey is the only downside."

Reviewed on Apr 15, 2024

Reefhouse Resort & Marina
Lime Tree Bay Resort
Lime Tree Bay Resort
3.5 out of 5
68500 Overseas Hwy, Long Key, FL
  • 3 hours drive from Duval Street
The price is $169 per night from Apr 28 to Apr 29
$169
per night
Apr 28 - Apr 29
Stay at this 3.5-star beach resort in Long Key. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"Great time!"

Reviewed on Apr 15, 2024

Lime Tree Bay Resort
Bayside Inn Key Largo
Bayside Inn Key Largo
3 out of 5
99490 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $175 per night from May 12 to May 13
$175
per night
May 12 - May 13
Stay at this beach hotel in Key Largo. Enjoy free WiFi, a private beach, and a 24-hour fitness center. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (1,225 reviews)
I” ll be back!
"Nice stayed! TJ was 😌 great"

Reviewed on Apr 18, 2024

Bayside Inn Key Largo
Holiday Inn Key Largo, an IHG Hotel
Holiday Inn Key Largo, an IHG Hotel
3 out of 5
99701 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $206 per night from Apr 28 to Apr 29
$206
per night
Apr 28 - Apr 29
Stay at this beach hotel in Key Largo. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the bar in our reviews. Popular attractions ...
8.2/10 Very Good! (1,002 reviews)
"Very nice stay. Property was beautiful and vey well kept up. Would definitely stay again."

Reviewed on Apr 16, 2024

Holiday Inn Key Largo, an IHG Hotel
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Baker's Cay Resort Key Largo, Curio Collection by Hilton
4 out of 5
97000 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $395 per night from Apr 24 to Apr 25
$395
per night
Apr 24 - Apr 25
Stay at this beach hotel in Key Largo. Enjoy 2 outdoor pools, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,000 reviews)
"great place to relax"

Reviewed on Apr 8, 2024

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Florida Keys

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Florida Keys hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Florida Keys.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Florida Keys’s 7,906 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $138. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Florida Keys hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Florida Keys. No matter your reason for visiting Florida Keys, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Florida Keys hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Florida Keys for as low as $138.

How many hotels are there in Florida Keys?

With over 7,906 hotels in Florida Keys, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $138.

How to find cheap car rentals in Florida Keys?

Finding a cheap car rental deal in Florida Keys is as easy as scoring cheap hotels in Florida Keys. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Florida Keys now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Florida Keys right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.