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Enterprise Vacation Packages

Enterprise Flight + Hotel packages

Prices and availability subject to change. Additional terms may apply.
Kasa Downtown Des Moines
Sonesta Simply Suites Des Moines
Motel 6 Altoona, IA - Des Moines East
Hotel Renovo
Iowa House
Gateway Hotel and Conference Center at Iowa State University
Motel 6 Des Moines, IA - North
Radisson Hotel Ames Conference Center at ISU

5-7 Night Vacations in Enterprise

Prices and availability subject to change. Additional terms may apply.
Iowa House
Gateway Hotel and Conference Center at Iowa State University
Motel 6 Des Moines, IA - North
Radisson Hotel Ames Conference Center at ISU

Cheap Hotel Deals in Enterprise

Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Stoney Creek Hotel Des Moines - Johnston
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

2.5 out of 5
7225 Vista Dr, West Des Moines, IA
Stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Fairfield Inn and Suites by Marriott Des Moines West
Surety Hotel

Surety Hotel

4 out of 5
206 6th Ave., Des Moines, IA
Stay at this 4-star hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast. Our guests praise the restaurant and the bar in our reviews. Popular ...
Surety Hotel
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Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Days Inn & Suites by Wyndham Des Moines Airport
La Quinta by Wyndham Altoona Des Moines

La Quinta by Wyndham Altoona Des Moines

2.5 out of 5
1785 11th Street NW, Altoona, IA
Stay at this business-friendly hotel in Altoona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
La Quinta by Wyndham Altoona Des Moines
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
Stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast, and room service. Our guests praise the restaurant and the helpful staff in our reviews. ...
Hotel Fort Des Moines, Curio Collection by Hilton
Econo Lodge Inn & Suites - Des Moines/Merle Hays Road

Econo Lodge Inn & Suites - Des Moines/Merle Hays Road

2 out of 5
4755 Merle Hay Road, Des Moines, IA
Stay at this business-friendly hotel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. ...
Econo Lodge Inn & Suites - Des Moines/Merle Hays Road
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave, Clive, IA
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
Wildwood Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines

Find cheap hotels in Enterprise

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Enterprise hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Enterprise.

Choosing the right hotel in Iowa has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Enterprise’s 682 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Enterprise hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Enterprise. No matter your reason for visiting Enterprise, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Enterprise hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Enterprise for as low as $65.

How many hotels are there in Enterprise?

With over 682 hotels in Enterprise, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.

How to find cheap car rentals in Enterprise?

Finding a cheap car rental deal in Des Moines is as easy as scoring cheap hotels in Enterprise. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Enterprise now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Enterprise right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.