Hotels Near
East Florence

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Featured East Florence Hotels

Renaissance Shoals Resort & Spa

Renaissance Shoals Resort & Spa

3.5 out of 5
10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (789 reviews)
"Quiet rooms, great food options, a very nice getaway."

Reviewed on May 25, 2026

Renaissance Shoals Resort & Spa
Residence Inn Florence Marriott

Residence Inn Florence Marriott

3 out of 5
1000 Sweetwater Ave Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Regency Square Mall and Children's ...
9/10 Wonderful! (353 reviews)
"The room was very large! Plenty room for family. The pool was beautiful. Also you can enjoy sitting around the firepit, there is an exercise room and also basketball area. Breakfast was excellent...It is large, alot of choices!!"

Reviewed on May 28, 2026

Residence Inn Florence Marriott
Budget Inn & Suites

Budget Inn & Suites

2.5 out of 5
1238 Florence Boulevard Florence AL
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.4/10 Good! (161 reviews)
"Basic room. Air worked great. They were in the process of a remodel. If you need a room with a bed to sleep in for cheap, this is your place."

Reviewed on Jun 6, 2026

Budget Inn & Suites
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,006 reviews)
"Clean room, comfortable beds, nice pillows, with an easy check in. Bathroom on the small side but overall great stay for the money!"

Reviewed on Jun 8, 2026

Days Inn by Wyndham Muscle Shoals Florence
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
Fully refundable
Book a stay at this business-friendly hotel in Sheffield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,009 reviews)
"Breakfast was better than most places. I would stay here again. You definitely get what you pay for here."

Reviewed on Jun 7, 2026

Clarion Inn Sheffield Muscle Shoals
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

2 out of 5
1852 Highway 72 E Tuscumbia AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,008 reviews)
"Very nice better than the last trip and stay in Biloxi"

Reviewed on Jun 7, 2026

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (873 reviews)
"The location downtown with open spacious renovated rooms and Big Bad Breakfast downstairs you just can’t beat this hotel when you’re in Florence."

Reviewed on Jun 7, 2026

The Stricklin Hotel
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (820 reviews)
"The worst coffee ever! Slamming doors and noise beyond all comprehension. No pool or hot tub, so it’s false advertisement on the Hotels.com website. Nice enough staff, but overall not worth the money and very disappointing."

Reviewed on Jun 3, 2026

Comfort Suites Florence Shoals Area
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
Baymont by Wyndham Florence/Muscle Shoals
Spark by Hilton Tuscumbia Muscle Shoals

Spark by Hilton Tuscumbia Muscle Shoals

3.5 out of 5
712 Hwy 72 W Tuscumbia AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (765 reviews)
"The breakfast was continental as stated but was hoping for eggs and meat. Also no coffee in the room. When I arrived to check-in the power was mostly out due to storms but the manager helped me get into a room and even carried my bag up three flights of steps. Great customer service from this ..."

Reviewed on Jun 4, 2026

Spark by Hilton Tuscumbia Muscle Shoals
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2.5 out of 5
180 Etta Gray Street Florence AL
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (624 reviews)
"HVAC unit in room was extremely noisy. Each time the unit came on there was excess noise that would wake you up."

Reviewed on Jun 7, 2026

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

2.5 out of 5
1934 Highway 20 Tuscumbia AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (656 reviews)
"The room was overall fine, keeping in mind it's inexpensive, on the side of the road, in Alabama. However, the sheets didn't fit the mattress properly, the desk chair was really old with the vinyl cover pealing off significantly, and there were cobwebs in the bathroom. I brought some breakfast up ..."

Reviewed on Jun 6, 2026

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in East Florence

Florence is a city that has a lot going on, but you have your sights set on East Florence. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that East Florence has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of East Florence hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the East Florence underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the East Florence city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of East Florence cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in East Florence at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $70
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the East Florence hotel you want, book it, and never look back. Because your great escape is ahead of you.